Bacterial Protein Structure Hints At Mechanism Of A Class Of Premature Aging Diseases
...cation, as had beenpreviously thought, RTP is more like a one way door, allowing the DNA replicationmachinery to move in only one direction along the DNA strand, the researcherssaid. They said the work has implications for human disease because RTPinteracts with a class of proteins known as helicases, whi...Florida Company Using ORNL Technology For Revolutionary Wheelchair
...ble Roving Omnidirectional VehicleReplacement). "I like to explain it by telling people this wheelchair is perfect forparallel parking," said co-inventor Stephen Killough of ORNL's Robotics andProcess Systems Division. "Because it is so highly maneuverable, it canalso go into tight corners." Killough and ...Scientists Discover Smallest Frog
...s that are the smallest, especially in a big group like tetrapods." Cuban scientists restricted by...f the biodiversity on this planet, including areas like Cuba that are very close to the United States."...Disease Resistance Mechanism Identified in Plants
...g microorganism. The avirulence protein acts much like an antigen in animals, eliciting an immune response from the plant. Researchers suspect that the resistance mechanism observed in tomatoes also occurs in many other plants. Their results appear in the December 20 issue of the journal Science . ...Mechanism For Disease Resistance Identified In Plants
...g microorganism. The avirulence protein acts much like an antigen in animals, eliciting an immune response from the plant. Researchers suspect that the resistance mechanism observed in tomatoes also occurs in many other plants. Their results appear in the December 20 issue of the journal Science . ...A Sensor, A Switch, A Zipper: Protein Engineers Design Potential Tool
... structure is composed of two helices that wrap like grape vines around each other. The design incorporated a selective binding site such that when the researchers added a small molecule, benzene, the two helices intertwined with a third to create a triple-helical coiled...Proteins Interacting With RNA And DNA Are Surprisingly Similar
...A. "You don't expect RNA-binding proteins to look like DNA-bindingproteinsbecause the structures in DNA and RNA are quite different," saidDavid Draper,a Johns Hopkins University chemist who isheading the research team that madethe discovery. Draper's team discovered that the RNA- and DNA-binding proteins...Laser Microscope At Cornell Images Serotonin In Live Cells
... not been possible. "There are molecules that act like pumps. They concentrate serotonin within a cell. We found very high concentrations, about 50 millimolar, in the secretory granules," he said. Williams is following the release of serotonin from a cell as it occurs after allergic stimulation. "The l...Researchers Corral Millions Of Microscopic Membranes
...s have been applied to an entire biological system like a membrane. They were able to do this by adapting ...hod identify and separate different kinds of cells like current methods, but it potentially could measure how well the cells are functioning, Groves suggest...Penn State Wetlands Project Seeks Scientific Evaluation Criteria
...pes they are modeled on. "A created wetland looks like a natural site, but it really doesn't behave like one," he says. Although Brooks says the wetlands assessment project has given resource professiona...Birds Deal With "Cocktail Party Effect"
...ethey can learn to mimic other sounds, even sounds like humanspeech that are not part of their natural world. That meant Icould work with synthetic as well as natural sounds to studytheir hearing abilities." To begin, the scientist trained birds to peck two differentkeys, one when they heard a rising......ogicaland natural resources in regional watersheds like Everglades and SouthFlorida, San Francisco Bay and...ects ofthe upstream floods on downstream resources like the Chesapeake Bay and SanFrancisco Bay. "We remain committed to our long tradition of setti...Stronger Evidence That Global Climate Change Can Reduce The Variety Of Life
... communities characterize warminterglacial periods like today (high tilt), while diversity dropssignificantly during glacial periods when global ice sheets expand in size(low tilt). The mechanisms that cause diversity to change are still unclear butCronin and Raymo propose that changes in solar ra...Scientists Determine 3-D Crystal Structure Of Cancer-Causing Protein
...ractions and containsdocking units. Normally, Hck, like the other members of the Src family, is"off," folded into a position much like a snake biting its own tail. In thisclosed position, SH2 binds to the phosphotyrosine in Hck's tail,...'BirdSource' Website For Citizen-Science Data
...to tune to the movements of bird populations, just like the weather reports track the movements of storm fronts. We will have up-to-the-minute accounts on where birds are at any given moment -- and so will anyone who opens BirdSource." Emphasizing the value to biological conservation of data gathered by ......grant. "The big picture is this: We are very much like the plant mutants. Humans cannot make vitamin C, ...od firm against those environmental stresses, much like humans stand up well against external stresses when they consume vitamin C. Last believes this rese...A Phoenix From A Ring Of Fire Is A Pattern For The Recovery Of Mount St. Helens
...ash from the "child" volcano "made all of us look like chimney sweeps." A celebrated entomolo...It settled on the hard, waxy shell, and then acted like sandpaper, stripping away the waterproofing layer. The insects lost moisture, and quickly died. "It...Molecular Imposter Rebuts Long
... a drug -- infiltrating cancerousor diseased cells like a Trojan horse and thenknocking them out by blocking genetic expression. Kool also plansto examine shape mimics for the other three DNAbases. Kool was joined in the research by postdoctoral researchersSean Moran and Rex Ren and graduate student ......d abrake pedal," says Ludlow. "The RB protein acts like the brakepedal, reining in growth in a precise and controlled manner.Disable that brake pedal and cells can grow out of control." The team's research is funded by the National Institutes ofHealth and by the Sally Edelman and Harry Gardner Cancer...