Landmark gene agreement announced by Samoan government and UC Berkeley for anti-AIDS drug Prostratin
...ibernation in the body's immune cells and into the line of fire of anti-AIDS drugs now in use. "Prostratin is Samoa's gift to the world," explained Samoan Minister of Trade Joseph Keil. "We are pleased to accept the University of California as a full partner in the effort to isolate the Prostratin genes."...Landmark agreement between Samoa and UC Berkeley could help search for AIDS cure
...ibernation in the body's immune cells and into the line of fire of anti-AIDS drugs now in use. "Prostratin is Samoa's gift to the world," explained Samoan Minister of Trade Joseph Keil. "We are pleased to accept the University of California as a full partner in the effort to isolate the Prostratin genes."...New study indicates arsenic could be suitable as first-line treatment in type of leukaemia
...t(15-17) negative AML would then be sub-divided in line with the World Health Organization's histologic classification system. The researchers believe that this would make sense because t(15-17) positive AML and t(15-17) negative AML have a totally different prognosis and need a different treatment approa...Joslin researchers clarify mechanisms for beta-cell formation
...derived from immature ductal cells--the cells that line the ducts of the pancreas.) And what signals this replication of beta cells to occur? To study these questions, Rohit N. Kulkarni, M.D., Ph.D., Jonathon N. Winnay, and C. Ronald Kahn, M.D., of Joslin Diabetes Center in Boston; Ulupi S. Jhala Ph.D......, is present in elevated amounts in the cells that line the intestines of celiac patients and can be stimulated by wheat gluten, via IL15, in cells grown in the laboratory. By expressing MICA, the intestinal cells provide a target for CTL cells that are simultaneously stimulated by IL15 to attack the inte...DuPont developing new protective suits for military, first responders
...e developed by DuPont that will help protect front line defenders from toxic industrial chemicals and military warfare agents. Through the process of selective transport -- the diffusion of water across a selectively permeable membrane -- this membrane allows sweat evaporation and body heat to escape to ...Sandia experiments may reduce possibility of future water wars
...collected every few minutes, will be sent by phone line to a remote computer for analysis. "We expect that the [greenhouse] system will not be as slow-moving or spatially homogeneous as one might think in terms of environmental change," Ron says. "Every time the water system pops on, the local temperature...Review article makes case for a new source of cells in the body
...hese cells might be used to establish a human cell line to enable his studies of the development and function of salivary glands. While the jury remains out on that question, the cells have helped Dr. Dickinson find new direction in his research: working to learn more about the cells Dr. Sohal first saw i...Improving crops without genetic modification natural variation holds the key
...mato species and a cultivated tomato species; each line had a single genomic region from the wild tomato inserted into the cultivated plant. They then combined three independent yield enhancing genomic regions from the wild species into the new plant line. Plants were grown over three seasons, during whic...Synthesized molecules studied as weapon to stop cell division in cancer cells
...in an ovarian cancer cell line. "That was the cell line that was available, but it should work for many cancers," Etzkorn said. "It would probably be particularly effective against breast cancer and prostate cancer. It seems to relate to secondary sexual characteristics." However, a lot of work remains to...Scientists reinvent DNA as template to produce organic molecules
...rve as a miniature, sequence-programmable assembly line for products of chemical synthesis. Because the resulting synthetic compounds are linked to DNA, techniques long used to screen and amplify the genetic mainstay can now be applied. Molecules can be "selected" for desired functional properties, and th...Restoring sweetgrass to the South Carolina lowcountry
...ited States, grows in clumps along the second dune line of the beach, in the boundaries between marshes and woods, and in wet savannahs. This "muhly" grass is not to be confused with the true sweet grass (Hierochloe odorata) used by Native American basket makers. Although three other plants -- palm, longl...Heartless worms hold clues to cardiac arrhythmias, sudden death
...nvestigators were able to take advantage of a worm line with a mutation in the worm version of HERG. The mutation, unc-103, causes profound neuromuscular defects, including a pharyngeal pumping defect that Petersen noticed as she learned to work with the worms. "I remember the first time I saw it (the pu...Embryonic stem cell therapy shows steady benefits in rebuilding infarcted heart
...ion Researchers took a murine embryonic stem cell line and engineered a cell clone to express fluorescent...cells. They tested the cardiogenic capacity of the line and collected cells with high potential for becoming cardiomyocytes. Randomly assigned rats that had...Tips from the journals of the American Society for Microbiology
...ing tooth loss. Bacteria accumulate along the gum line initiating an immune response. "Gingival immune responses have been associated with the pathogenesis, severity, and genetic susceptibility to human periodontal disease," say the researchers. In the study researchers compared gene expression in the g...Progress in breast cancer progression
... to be able to invade other tissues. Using a cell line that would undergo this transition when given a growth factor, the authors showed that when NF-kB activity was blocked, these cells could not undergo the transition. Furthermore, if the NF-kB pathway was over-activated, the cells no longer required ...JCI table of contents, 16 August, 2004
...s to be able to invade other tissues. Using a cell line that would undergo this transition when given a growth factor, the authors showed that when NF-kB activity was blocked, these cells could not undergo the transition. Furthermore, if the NF-kB pathway was over-activated, the cells no longer required ...Nerve cells 'guided' to repair spinal damage: Technique
... Engineering. "A longitudinal channel - a straight line - is the minimum distance between two points." The research, which has yet to be tested in animal models or humans, was funded by the Natural Sciences and Engineering Research Council of Canada and an Ontario Graduate Scholarship in Science and Tech...ASU researchers demonstrate new technique that improves the power of atomic force micrscopy
...l Academy of Sciences. The article is available on line at http://www4.nationalacademies.org/nas/nashome.nsf "If you imagine that all proteins are shaped like Lego blocks, then conventional atomic force microscopy (AFM) is feeling the Lego blocks on the floor, but it can't tell the difference between one ......more than 430 photographs, including 152 in color, line drawings and other illustrations. Campbell teamed up with two others to compile the book: her father, John R. Campbell, former president of Oklahoma State University and former dean of the College of Agriculture (now the College of Agricultural, Cons...