Fly Tumor Points Way To New Understanding Of Cancer Development
... thattheir achievement represents the first direct link between human tumorsuppressor genes and those found in the fruit fly Drosophila . More broadly, the experiments demonstrate that even though flies and humansare separated by 800 million years of evolution, the insects can provideimportant new insig......ellular protein-protein-interactioncascades. These link Neuroligins to components of the postsynaptic signaltransduction machinery and b-Neurexins to the presynaptic transmitter secretionapparatus. Based on their findings, Brose and colleagues suggest a novel molecular model ofsynapse formation in the bra...Scientists Discover Key Cog In Receptor That Governs Ripening
...tists have found an ion of copper -- and a genetic link to someof the oldest life forms on the planet. The discovery reveals another key component of the ethylene receptor, a proteinsensor that helps plants detect the slightest whiffs of ethylene, a gaseoushormone that prompts fruit to ripen and flowers t...Cedars-Sinai Scientists Localize New Ataxia/Epilepsy Gene
...s suffering from the disease, indicates a possible link withepilepsy. Further study of the new gene is expected to shed new light not onlyon ataxia, a relatively rare inherited disease that affects one in 10,000persons, but also on the pathogenesis of epilepsy, a condition that affects onein 100. LOS ANGE...In The Genes: Extra Belly Fat, Insulin Resistance Linked
...tigator for thestudy. The researchers explored the link between diabetes and the thickness of thisinner fat layer in Caucasian families who already were participating in a largergenetics study. As part of the Heritage Family Study, four field centersevaluated the volunteers: the University of Indiana, Tex...Amphibian Revival: Build It And They Will Come
...phibians live in water and on land and are a vital link in the foodchain, they are considered to be a bellwether environmental species. Since thelate 1980s, conservation biologists have reported alarming declines in amphibianpopulations in various parts of the world -- from Central and Latin America, tot...Protein Adultery Revealed!: Mechanism Of Protein Folding Captured In Computer Simulation
...o acid on a second protein, rather than waiting to link to oneon its own chain. This protein "adultery," which occurs as each protein passes through a series ofintermediate folding steps, results in proteins stuck to each other in inertmasses. It is easy to see why proteins might grab at each other. Prot...... them. But this research has not yet completed the link to actin. Van Vactor's work bridges that gap by describing the first continuousline of communication linking a receptor in a growth cone's membrane to actin,the final agent of change. The cell's cytoskeleton is a continuously changing...Scientists Study Protein's Role In Tumor Development In Fish
... One theory Holzschu is investigating is a link between hormonal changesthat occur during spawning and tumor regression. It's possible these hormonesmay have a direct effect on the tumors, or on the cyclin, which in turn couldprompt tumor cells to undergo apoptosis, or programmed cell death. ...Salmon Syndrome M74: Cause Still A Mystery
...enconsiderably lower. Researchers long suspected a link with environmentalpollutantssuch as chlorinated organic compounds (PCB, dioxins, etc.), no such link has notbeenconfirmed. No evidence has been found that heavy metals, bacteria or viruses areassociate...Mechanism For Fungal Adherence Found, Possible Key To Disease
...ilaments uses the enzyme to link to the protein in the epithelialcells, it forms a covalent bond -- the strongest type possible --giving it great adhesive capabilities. This type of covalentadhesion has not been de...Bacteria From Gum Infections Associated With Diabetes, Chronic Lung Disease, UB Studies Find
...ase was designed to follow up earlier reports of a link between poororal hygiene, gum disease and chronic lung disease, also using data from NHANESIII. Frank Scannapieco, D.M.D, Ph.D., assistant professor of oral biology, analyzeddata from 13,792 adults concerning the incidence of pneumonia, asthma,bron...Iron Supplemented Formula Milk Should Be Free For Inner City Children Into Their Second Year Of Life
...edical School argues that the evidence of a causal link between iron deficiency and developmental difficulties is still unclear and that further research in this area is urgently needed. Contact: Professor Ian Booth, University of Birmingham, Institute of Child Health, Birmingham i.w.booth@bham.ac.uk Stu...Investigators Identify Suspect In Search For Stress-Sniffles Link
...ave identified what may be an important biological link betweenstress and the common cold. The culprit: i...University in Pittsburgh had earlier found a clear link betweenpsychological stress and a propensity to be infected by respiratory viruses. The new work by...Studies Document Ease Of Ecosystem Disruption
... firstexperiments of its type to document a direct link between small temperaturechanges and the effects of a keystone species. "Different species interact constantly through such mechanisms aspredation, competition and disease," Sanford said. "Because of that, an impacton a keystone species may ...Alcoholics' Children: Living With A Stacked Biochemical Deck
...activity of specific brain circuits mostscientists link with alcoholism, and that those differences exist before theonset of heavy drinking," says neuroendocrinologist Gary S. Wand, M.D., who leda team of Hopkins researchers. The study was reported in the December Annals ofGeneral Psychiatry. "T...Sustainable Harvest Of Caiman Falls Short Of Potential
...e central government treasury, breaking the direct link between sustainableharvest of wildlife and conservation. The link between sustainable harvest and conservation is further threatened bythe increase in crocodilian far...Alzheimer's Disease And Developmental Biology Linked Through Single Molecule
...ing process -- that the new papersshow a promising link between the fields of Alzheimer's disease neuropathologyand developmental biology. "What we can learn from the effect of presenilin on the cleavage ofNotch may be directly applicable to better understanding APP processing, leadingto new insig...American Red Cross Launches New Genetic Screening Technology To Directly Detect Viruses
...Red Cross performed unlinked testing, severing the link between the donorand sample, to validate the processes and systems newly created for NAT. RedCross tested more than 180,000 samples during unlinked testing. Based on favorable test outcomes, the Red Cross began screening blood donationswith NAT at t...Researchers Convene To Discuss New Findings Linking DNA Repeats To Human Disease
...seasewill share their cutting-edge findings on the link between unstablemicrosatellites - DNA repeats - and Fragile X syndrome, Huntington's disease,Friedreich's ataxia, Kennedy's disease, Spinocerebellar ataxias, and musculardystrophy. Conference co-sponsored by the University of North Carolina Programi...