Case for IBD combination therapy comes from research at Baylor, MIT and Hebrew University
...D by membrane-anchored phospholipase A2 inhibitors linked to glycosaminoglycans: novel multi-functional anti-inflammatory drugs. Researchers at Saul Yedgar's laboratory at the Department of Biochemistry, Hebrew University, Hebrew University-Hadassah Medical School, Jerusalem, Israel, include Marina Kleiman,...New treatment for fibromyalgia
...its cause remains a mystery, fibromyalgia has been linked to abnormalities in the brain's neurotransmitters, serotonin and norepinephrine--chemicals key to mood and widely recognized for their role in depression. Not all patients with fibromyalgia, however, have depression or respond to antidepressants. Tre...OutFoxed! New research may redefine late-stage cardiac development
...eart development including those that are directly linked to congenital heart disease" says Morrisey....New research suggests link between maternal diet and childhood leukemia risk
...onducted a systematic survey of a woman's diet and linked it to the risk of childhood leukemia," said Dr. Ke... number of scientists believe that genetic changes linked to cancer later in life begin in the womb. "It goes back to the old saying to expectant mothers, 'Yo...Sandia experiments may reduce possibility of future water wars
... "We envision these [futuristic] sensors linked together [via wireless communications], possibly on every plant, so the plant tells the control system directly what it needs, instead of merely monitoring air around the plant. The plant may have other needs these [more distant sensors] don't tell u...Rensselaer marks the opening of the center for biotechnology and interdisciplinary studies
.... Low Center for Industrial Innovation. It will be linked by a new pedestrian walkway west to the Experimental Media and Performing Arts Center (EMPAC) now under construction. The Center's red brick faade on 15th Street mirrors the historic Georgian-style architectural features of the Ricketts campus to the...Optimizing protein's 'death domain' halts leukemia in laboratory study
... helix. Crucially, the artificial amino acids were linked to each other by a pair of hydrocarbon subunits. Like a reinforcing metal staple, Walensky explains, these links held the peptide in its natural coiled configuration. Further experiments confirmed that the stapled BH3 alpha helix retained its biologi......Deregulation of BMP pathway activity has also been linked to some tumor growth. To test whether or not BMP4 is indeed a growth mediator, they used techniques from gene therapy and protein delivery to mis-express BMP4 and its antagonist. "The results," Chuong says, "were astounding. The chicken beaks were mo...Chernobyl study: Risk of thyroid cancer rises with radiation dose
...oup began its studies of thyroid cancer, a disease linked to radiation exposure. By the early 1990s, many new cases of the disease, particularly among young children, were diagnosed in regions near the blast. Since then, reports show several hundred cases of thyroid cancer in young children in the three cou...DHA-rich diet protects brain from Alzheimer's damage, UCLA study shows
...ith genetic mutations that cause the brain lesions linked to advanced Alzheimer's disease, the UCLA researchers created a mouse model to test environmental risk factors for the disorder. When the mice developed the lesions, but showed minimal memory loss or synaptic brain damage, however, the scientists to...Convulsions in worms mimic epileptic seizures
...he LIS1 gene. In its human form, the gene has been linked to a rare birth defect called lissencephaly, which affects one out of every 30,000 children born. In children with lissencephaly, the normally wrinkled surface of the brain's cortex is smooth. They also have mental retardation and severe epilepsy, th...NASA satellites detect 'glow' of plankton in black waters
...is an example of how land and ocean ecosystems are linked together. "Coastal and land managers over large areas need to work together, to alleviate more black water events from taking place in the future," said Muller-Karger....How an insidious mutation fools DNA replication
...piral staircase. The two strands of the spiral are linked by sequences of molecular subunits, or bases, called nucleotides. The four nucleotides -- guanine, cytosine, adenine and thymine -- naturally complement one another like puzzle pieces. In normal DNA, a guanine matches with a cytosine, and an adenine ...Protein fishing in America: The movie
...r not binding. How the binding and not binding are linked is hidden information."Lu's single-molecule spectroscopy technique gathers and analyzes photons emitted as single proteins interact. This raw data may not produce what we would think of as a motion picture, but for Lu it is just as good. It enables h...University of Pittsburgh receives $10 million grant for head and neck cancer
...Activators of Transcription (STATs) that have been linked to tumor progression in several cancers, including head and neck cancer. These proteins represent a critical survival pathway in head and neck cancer because they activate a protein, BCL-X, that interferes with apoptosis, or cell death. By targeting ...Meteorites supplied Earth life with phosphorus
...ng chains. It is vital to metabolism because it is linked with life's fundamental fuel, adenosine triphosphate (ATP), the energy that powers growth and movement. And phosphorus is part of living architecture it is in the phospholipids that make up cell walls and in the bones of vertebrates."In terms of mas...Testing the fitness of biological clocks
...hat the benefits of biological clocks are directly linked to environments with regular day/night cycle and totally disappear in conditions of constant illumination. "Circadian clocks are so widespread that we think they must enhance the fitness of organisms by improving their ability to adapt to environment...Scientists reinvent DNA as template to produce organic molecules
...sis. Because the resulting synthetic compounds are linked to DNA, techniques long used to screen and amplify the genetic mainstay can now be applied. Molecules can be "selected" for desired functional properties, and the survivors of these selections can then be copied using the polymerase chain reaction (P...... of the wild-type gene on the DNA and are directly linked to mildew resistance. "The repeats are read along with the normal gene," explains Schulze-Lefert. "The original reading frame cannot be recognized anymore and the MLO protein is therefore no longer produced in the cells." Even in the rare cases where...Study suggests cell-cycle triggers might be cancer drug targets
...These same proteins, when overly active, have been linked to cancer cell proliferation. With one significant exception, the absence of proteins called cyclin D1, D2, and D3 seemed to have no deleterious effect on development of the tissues and organs of laboratory mouse embryos. "D-type cyclins" are molecul...