Tag: "linking" at biology news

Scientists to prototype cyberinfrastructure for research and education access to ocean observatories

...ndividual wavelengths of light on optical fibers), linking UW and UCSD will form LOOKING's optical core, with plans for eventual links to NASA research centers, institutions in Mexico and Canada, as well as other U.S. universities that do ocean research. Researchers at the University of Illinois will provide...

Research suggests new avenue for stopping, preventing colon cancer

...s internationally known for his pioneering studies linking the development of colorectal cancer to the cyclooxygenase-2 (COX-2) enzyme. COX-2 is a major target for drugs that relieve the pain and inflammation of arthritis, but COX-2 gene expression is also elevated in a variety of malignancies including colo...

Students build submarine to track Octopuses

... Prince William Sound, with a communications cable linking it to a mother boat on the surface. Divers checked it for leaks, while UA Professor Emeritus Tom Vincent and UA Mechanical Engineering senior Patrick Haley tested its robotic vision, motors and internal computer. Along the way, it encountered and fil...

Washington University in St. Louis leads group studying aging process

...sses the integrative approach to studying biology, linking the disciplines of systems and computer science bioinformatics -- with genetics and molecular biology genomics. The FIBR program is removing the limits biologists have found increasingly frustrating in recent years when seeking funding and finding...

A liking for sweets, combined with novelty seeking, may predict alcoholism

...It is intriguing that Dr. Kampov has some evidence linking this personality trait with sweet liking to indicate a higher risk for alcoholism. Researchers examined 165 middle-aged patients admitted to a residential treatment program for alcohol, drug dependence, and/or interpersonal problems related to substa...

Images of 'tail' of protein needed for cell multiplication suggest anticancer drug targets

...obbled together. The workshop makes the switch by linking a tag called NEDD8 with its "target" a molecule called Cul1. NEDD8 then modifies Cul1, causing it to set off a cascade of biochemical reactions that eliminates the molecular brake controlling cell replication. In the absence of this brake, cell repli...

Case for IBD combination therapy comes from research at Baylor, MIT and Hebrew University

...y drugs (MFAIDs) that address both these needs, by linking PLA2-inhibiting lipids to GAG. They report that MFAIDs, given IP, IV or orally, have been effective in treating animal inflammations including endotoxin-induced sepsis, and IBD induced by TNBS, indomethacin or DSS measured by survival, histological, ...

Smac-ing back at cancer cells

... the chemical reactions, we actually made a dimer linking the molecules in pairs. That dimer, Compound 3, turned out to be much more active." The scientists believe the twinned molecule is more active because the Smac protein itself is a combination of two identical proteins, although the reason for Compoun...

Modest climate change could lead to substantially more and larger fires

...g state-of-the-art global climate models. "Models linking area burned in the Western states with fire-season temperature predict that global warming will bring significant increases in fire extent," said Donald McKenzie of the USDA Forest Service's Pacific Wildland Fire Science Lab. "Such increases could ha...

Better living through urban ecology

... the Institute of Ecosystem Studies, comments, "By linking studies of human populations and social institutions with traditional ecological studies, BES research has revealed unexpected patterns and processes in the Baltimore ecosystem. Renewed funding will allow us to investigate the ecological and social f...

Study suggests cell-cycle triggers might be cancer drug targets

...d cancers. The main function of the D cyclins is a linking one. They respond to signals outside the cell and turn the cell-cycle machinery on when needed, enabling the cell to adjust to changes in environment. How this process is carried out in the mouse embryos with no D-type cyclins is a puzzle, says Sicin...

Newly discovered protein may be key to muscular dystrophy

...t extends through the entire muscle cell membrane, linking the framework inside the cell to the region outside of the cell. The complex is found in C. elegans, in mice and in humans. In each species, defects in the complex can cause muscle degeneration, but the exact role of the complex in disease has not be...

International symposium on nutritional genomics

...es. The symposium will present the latest findings linking diet and genes to heart disease, diabetes, asthma and some cancers. Nutritional genomics is the study of how diet and genes interact to influence health and disease. It's well known that diet choices are linked to obesity and chronic diseases such a...

Full promise of genomics in disease research yet to be realized

...at a "common thread" genetic sequence may be found linking pathogens of wildly different species, says the report. Finding such a "Rosetta Stone" of pathogenesis could ultimately expedite disease control and prevention. For continuing progress the report specifically recommends greatly increasing the libr...

Scientists pinpoint molecules that generate synapses

...n two neurons to commence development of a synapse linking them. Umemori spent several years scanning neuron... these pioneering molecules that set in motion the linking of neural networks. In the end he fingered a molecule called FGF22, along with several of its close ...

Study supports association between HPV infection and head and neck cancer

...rson Cancer Center in Houston, review the evidence linking HPV infection with HNSCCs. "Understanding how the [HPV] viral proteins interact with cellular proteins and/or DNA in host cells may allow us to design strategies to block malignant transformation," they write. "The promising results from a trial of a...

Chemoradioimmunotherapy for advanced breast cancer: hope for the future?

... therapeutic index." "Introducing the radiation by linking the radioisotopes to the anti-HER-2 antibody is more efficient than conventional external beam radiotherapy because the radiation is targeted specifically to those breast cancer cells that over-express HER-2/neu, leaving normal cells unaffected and t...

As humans alter land, infectious diseases follow

...of recommendations to address the issue, including linking land use to public health policy, expanding research on deforestation and infectious disease, the development of policies to reduce "pathogen pollution," and the establishment of centers for research and training in ecology and health research. "Whil...

Mice with hyperactive Wnt10b gene eat all they want, but have half the body fat of normal mice

...d an artificial sequence of DNA called a transgene linking Wnt10b to another gene called the FABP4 promoter, which is expressed only in adipose tissue," Longo says. "We injected the transgene DNA into fertilized mouse eggs and bred mice that inherited the new gene to create the animals used in our study. Und...

Noah's modern ark: The role of ART in conserving endangered species

... something that we call metapopulation management linking zoos to nature. In this case, I could see ART being used to collect sperm from wild giant pandas to help infuse new genes into the captive population, which is producing so many offspring now that reintroduction will be possible. All of this will b...

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