Newly developed tool aids study of Fragile X syndrome
...brain tissue. So we feel that he has been able to localize the culprits in the act, so to speak." Now, Weiler said, the entire group of proteins identified by APRA needs to be studied. "Now we can go on to define what it is that Fragile X patients are most basically needing -- in what part of the brain and ...Barn owls steer Stanford researcher to clues about visual and auditory mapping
...ey were wearing lenses. "For an owl to be able to localize the sound correctly after wearing the prisms it has to be able to forget the older map, which is not behaviorally appropriate, and follow the new map," said Weimin Zheng, PhD, a postdoctoral fellow in Knudsen's lab at the time. Forgetting the older m...Stem cells delivered into back of eye hold promise for people with retinitis pigmentosa
...tem cells, once injected into the mouse eye, would localize to a type of star-shaped glial support cells called astrocytes. During prenatal human development, astrocytes guide endothelial cells into place where they can proliferate and form blood vessels. Later in life, under certain circumstances, astrocyt...Building a better atlas of yeast proteins
...s for red fluorescent molecules that were known to localize to one or another specific cell structure. Such structures might include the mitochondria -- the cell's power plant -- or the golgi apparatus, which is a network of internal cell membranes. When the researchers saw both red and green fluorescence at ...JCI table of contents, 15 October, 2003
... the cell surface is also suggested to help PDGF-B localize in or near ECs. Betsholtz and colleagues found that without this motif pericyte recruitment was limited, and existing pericytes were partially detached from the vessel wall, which resulted in hemorrhaging. The report supports the notion that pericyte...New roles for protein modifications in cell migration
... with deficient glycosylation sites also failed to localize at the gonad and showed no ability to direct its migration. Genetic analyses revealed that MIG-23 is expressed in muscle cells, which reconciles well with MIG-17fs muscle cell origins. Taken together, these results indicate that MIG-17 molecules are ...Proteomics and alcoholism research
...ect, said its mission would be to characterize and localize proteins in both normal and diseased human liver. "The plan is to involve multiple laboratories internationally," she said, "to build an international network of experts in liver cell biology, proteomics and bioinformatics, and to develop a common b...Purdue scientists: To stop cancer, keep your Icmt away from your Ras
...ion of Ras and effectively breaking its ability to localize to the plasma membrane. "This effort depended o...ently that this lack of a methyl cap causes Ras to localize in the wrong region of the cell and, importantly, results in a Ras protein that cannot support cance...Jennie Hunter-Cevera wins 2004 USFCC/J. Roger Porter Award
...spectroscopy and stable carbon dioxide isotopes to localize bacteria and characterize their biological activity. An elected Fellow of the American Academy of Microbiology, Hunter-Cevera received her B.A. in biology and M.A. in microbiology from West Virginia University, Morgantown, and her Ph.D. in...LICR/UCSD team solves mystery of centromeres
...work demonstrates the ability of DXMS to precisely localize proteinfeatures responsible for function, even when the function is a very complex one in this case, the initiation of centromere formation." ...Yale digital diagnostic technology is basis of new company, HistoRx Inc.
...ated Quantitative Analysis) enables researchers to localize and quantify proteins in tissue while maintaining spatial relationships -- a process that was previously impossible with conventional methods of pathology analysis and which vastly increases the quality and amount of information for analysis. ...