Gene helps regulate longevity in flies, and perhaps humans
...n's disease and mood disorders. Now, regulation of longevity may be added to this list. Three natural variants...fect for a gene affecting a complex trait, such as longevity or body size, which is typically controlled by many genes with relatively small effects," said Dr. T...Hydrothermal vent systems could have persisted millions of years, incubated life
...eafloor very early in Earth's history." As far as longevity and stability, it's possible that black-smoker systems might last as long as 100,000 years but it's unlikely, Kelley says. That's because black-smoker systems typically form where new seafloor is being created, a process that even if a volcanic erup...Scientist proposes new theory of aging
...y and reproduction for the evolution of a species' longevity and long-term survival. The new theory, proposed b...ectancy. This suggests that nurturing behavior and longevity evolved together over time. The hypothesis appears in the Proceeding of the National Academy of Scie...Mutant gene found to cause early ovarian failure in mice
...oreover, the same pathway has a role in regulating longevity in several species. Premature ovarian failure itself results in the early onset of several age-related conditions in women, and the affected mice showed some other subtle signs that might indicate early aging. "Analyzing this pathway in great detail ...Pitt researchers find genes for depression; Play role in mood disorders, shorter lifespan
...er. Of equal interest is a secondary finding that longevity in the families who carry these genes is significantly reduced. The survey revealed 19 loci small regions on chromosomes where genes reside that appear to influence susceptibility to depressive disorders. The results extended the investigators' pr...Scientists find what type of genes affect longevity
...s offer clues to increasing human youthfulness and longevity as well. Using DNA microarray technology, the rese...er genes. But the finding left unanswered just how longevity is achieved. What are the genes that daf-16 regulates? The new research shows that several key sys...Close communication between identical twins helps them live longer
...fact that close communication has an effect on the longevity of identical twins indicates there is something sp...te. Several earlier studies have demonstrated that longevity is influenced not only by smoking, exercise and alcohol use, but also by social networks in people's...Researchers discover common cause for aging and age-related disease
...r related pathways have since been shown to affect longevity in fruit flies and mice and are likely to control life-span in humans as well. In neurodegenerative Huntington's disease, brain cells produce proteins with an abnormally high number of repeating subunits called glutamine. The proteins aggregate, disr...Drug combination increases life span of mice with ALS
...ing the onset of the disease and in increasing the longevity of the ALS mice." "The results are very impressive," says Dr. Angela Genge, director of the ALS clinic at the Montreal Neurological Institute and Hospital. "The approach that Dr. Kriz and Dr Julien use is uniquely helpful in screening for potentiall...New species of earliest-known salamanders found in China
...ers are disappearing worldwide today despite their longevity over evolutionary time. Here is an animal that has been around for at least 165 million years, Shubin said. They made it through several major extinction events. They made it through the event that killed the dinosaurs. Yet today, along with other am...[Mis]understanding village abandonments
...rn, supplemented by squash and beans. The relative longevity of settlements was often tied to specific agricultural practices, weather rainfall or irrigation dependent, and the availability of wild plant foods and game. Cordell added that settlement and movement not only depended on the successes of farming pr...Why we are what we eat: New links between our biology and food choices
... and eating more meat--and doing it for longer, as longevity increased--meant that early humans were consuming more fatty acids and cholesterol. The body's method for turning these substances into energy produces harmful free radical molecules, which can, over time, damage tissue through a process known as "o...The war against anti-aging medicine
... own research in the decades ahead, such as active longevity free from disability and functional dependence....Structure of cog at the hub of metabolism reveals anti-ageing function
...nase opens up new leads in the quest to understand longevity and ageing. "It now appears that a wide variety of genetic disorders including muscle and neurodegenerative diseases, and tumour formation, are caused by defective forms of this enzyme - as a result of increased free radical formation." "The challeng...Structure of pain-modulating enzyme described by scientists at the Scripps Research Institute
...because by inhibiting FAAH, you would increase the longevity of anandamide molecules--preventing their breakdown and allowing them to continue providing some natural pain relief. The structure that Cravatt, Stevens, and their TSRI colleagues solved should form a template for designing specific inhibitors that...Experimental 'gene switch' increases lifespan with no ill effects
...t silencing a key gene only in adulthood increases longevity with no effect on reproduction. The focus of the r...the hormonal pathways controlling reproduction and longevity act independently and can be decoupled. Typically, to study a gene's effect, researchers knock out t...Upside-down flies may offer clues to aging in humans
...diseases in humans. A team of researchers studying longevity in more than 200 male Mediterranean fruit flies found that nearly all of the flies in their study went through such an upside-down period, usually late in life. During this phase, the flies spent increasingly more time resting on their backs, even th...Researchers aim to control treatment-resistant head lice
...nfestation are certainly higher," Clark said. "The longevity of effective control provided by permethrin is in serious jeopardy unless effective monitoring of this resistance is begun and coupled with the use of new and novel acting pediculicides." Permethrin is a neurotoxin that kills nonresistant lice by at...Biomarkers of aging news advisory
...caloric restriction in monkeys have been linked to longevity in men, according to scientists at the National In...ers of caloric restriction in animals and extended longevity in humans who apparently do not stringently limit their caloric intake. The short correspondence app...Case Western Reserve University researchers developing new treatment for cardiovascular disease
...rotein adsorption to the liposome and increase its longevity in the bloodstream," Marchant said. "Current liposome systems only last approximately 12 hours as opposed to a normal red blood cell, which can circulate 120 days. We plan to evaluate the circulation lifetime in mouse models." Marchant believes that...