Tag: "longevity" at biology news

Stem cells could determine how long we live

...He and Van Zant think the same correlation between longevity and stem cell hardiness will be found in all mammals. All cells have mechanisms for repairing their DNA, which is under constant barrage from everything from radiation to free radicals. The notion that ageing happens because genetic mutations accumul...

Caloric restriction research: moving from lab animals to humans

...n humans that could plausibly explain the observed longevity of lab animals associated with CR. They also wrestled with the appropriate CR model in humans. Is it being thin over most of adult life or not gaining weight over time or expending more calories than eaten or eating fewer calories? And more important...

Tomato packs more cancer-fighting punch

..."They may stabilize membrane networks that involve longevity of physical structures in the cells called chromoplasts," Mattoo says. "Because lycopene accumulates in chromoplasts in the tomato fruit cells, in this case the polyamines seem to have a positive effect." The polyamines share a precursor with a plant...

Although controversial, stem cell therapies exhibit potential in biotechnology markets

...eatments are available, such as gene therapy, the longevity of benefits from stem cell treatment provides a tantalizing option for researchers. Heated controversy has arisen over the ethics of using embryonic stem cells, extracted from either very early embryos or fetuses. The United States has now limit...

'Nature' report: Researchers genetically alter mosquitoes to impair malaria transmission

...es not affect the fitness of a mosquito, including longevity or egg production. This is important because one of the challenges to using insecticides is that once spraying stops, a biological niche remains. If there was a large population of mosquitoes in an area to begin with, that means conditions are approp...

Still waters? 'Clear-cutting' robs the deep-sea of ancient treasures

...deep, where the "glacial pace of life" and extreme longevity make fish particularly susceptible to depletion and possible extinction. "We could be losing [deep-sea] species far more quickly than we can describe them," Roberts warned. Indeed, a world "we cannot yet imagine" lies deep beneath the seas, but undis...

Keep young and beautiful

...es to open up new leads in the quest to understand longevity and ageing, says Tom Kirkwood, an expert on ageing...ree radicals. But far from having to pay for their longevity with a weaker constitution, the PBA flies survived better than the controls. "We are going to test m...

Stem cells for eggs and sperm also control aging in roundworm

... the life of the animal. Their role in controlling longevity was unexpected. Earlier research in the Kenyon lab had shown that a protein known as DAF-16 is a crucial player in the route by which the reproductive system controls lifespan. DAF-16 is a transcription factor a protein that activates genes in respo...

Common variation of 'klotho' gene associated with human life expectancy

...sed on genes that might be responsible for extreme longevity (greater than 100 years) in specific groups of people. Klotho, by comparison, is relevant at much earlier ages. "What's so striking about the klotho variant is that it is relatively common and has its effect by age 65," explains Dan Arking, Ph.D., wh...

University of Cincinnati geologist finds survival benefit to evolving after mass extinctions

...sil genera compiled by J. John Sepkoski to examine longevity trends throughout the Phanerozoic (the last 540 mi...bins" or substages. Then, he looked at the average longevity of genera originating in each bin. Significant peaks in mean longevities occurred in the substages f...

Science Report: Super-crocodile crawls out of the African Cretaceous

...ze, says the Science study team. This surprising longevity for a crocodilian suggests that Sarcosuchus attained its mammoth proportions by extending the duration of its growing time, rather than speeding up its rate of growth like most dinosaurs, says Sereno. The new Sarcosuchus skulls have long snouts, ...

Cancer-preventing gene protects against stress and extends life span in worms

...ainst cancer and environmental stress and promotes longevity has been identified in studies of a nematode worm, according to a report to appear in Science Magazine and published September 14 on the Science Express web site. The discovery by a research team at the University of California, Santa Barbara provid...

Scientists identify chromosome location of genes associated with long life

...land Centenarian Study. Many investigators thought longevity was far more complex a trait that wouldnt be influ...udy, We have known that only a few genes influence longevity in lower organisms and that now appears to be true in humans. One in 10,000 Americans is a centenari...

Does chromosome 4 hold the secret to human longevity?

...d to the identification of a few genes that confer longevity in humans. They also believe that their studies ma... Deaconess Medical Center. "It is clear to us that longevity has a genetic component," said Kunkel. "Frequently, if there is one sibling who has lived to be a hu...

SAGE pronouncements on long life

...Research, researchers report genes associated with longevity in the worm Caenorhabditis elegans. Their results...sults provide hot new data for scientists studying longevity and showcase SAGE as a tool for studying global gene activity patterns....

Major fossil find reveals Asian origins of salamanders

...ution is so common in salamanders. Despite their longevity over evolutionary time, salamanders today are disappearing worldwide. "Here is an animal that has been around for at least 150 million years. They made it through several major extinction events. They made it through the event that killed the dinosau...

Scientists selectively activate "cell rescue" pathway in bone cells

...way alone, the scientists were able to promote the longevity of osteoblasts, the cells that lay down new bone, without sparking other sex steroid activities within the cell. Preserving osteoblasts could help prevent osteoporosis, a bone-thinning disease, which is a major health risk for 28 million Americans, t...

Genetic therapies for aging will face many challenges

...s of proteins may be important in the evolution of longevity among species. But Martin points out that the proteins of chimpanzees are 98 to 99 percent identical to those of humans, and yet chimps live only about half as long. So Martin says the difference in species-specific life spans may be largely due to v...

Ecologist wins international award

...rancs and deliver a lecture based on his work with longevity in Blanding's turtles, in July 2001 at the World Congress of Gerontology in Vancouver Canada. "It is an honor, and quite a surprise, be recognized by the Foundation IPSEN and scientists studying aging,? said Congdon. ?It is not often that a biologi...

Lung function may predict long life or early death

... that lung function was a significant predictor of longevity in the whole group for the full 29 years of follow-up. "It is important to note that the risk of death was increased for participants with moderately impaired lung function, not merely those in the lowest quintile," Schnemann said. "This suggests th...

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