In the obese, metabolic adaptations post-weight loss lead to regaining of shed pounds
...hed obesity, EO). These rats were then placed on a low fat, energy restricted diet that would produce a 1... allowed to regain weight with at-will access to a low fat diet for eight weeks before being examined. Three other separate groups were employed as control...Chemical Society announces EPA awards for environmentally friendly technology
...surfactants are readily biodegradable, demonstrate low toxicity and are produced in a fermentation process from renewable resources. These naturally occurring biosurfactants have been used to recover hydrocarbons from oil sludge, to facilitate petroleum storage tank cleaning and for a wide variety of bio...Study: Artificial sweetener may disrupt body's ability to count calories
...he consumption of artificially sweetened foods and low viscosity, high-calorie beverages, said Swithers, a developmental psychobiologist. "Incidence of overweight and obesity has also increased markedly during this period," she said. "Our hypothesis is that experience with these foods interferes with the...Early dexamethasone exposure has long-term neurodevelopment, neuroendocrine effects
...esda, MD -- Any parent of a newborn with extremely low birth weight (ELBW) faces the possibility that their child will be diagnosed with severe respiratory distress syndrome, which results in ventilator and/or oxygen dependency, and subsequent onset of chronic lung disease. Until recently, early administ...Earliest evidence of hereditary genetic disorder discovered by Hebrew University researchers
...elf in tooth enamel that is abnormal in structure, low in mineral content and hence subject to rapid wear and chipping. The Hebrew University researchers confirmed the clear presence of the disease in the fossil sample through x-ray and scanning electron microscope analyses. The disease appears relativel...Oxford Journals takes bold step towards free access to research
... memberships would keep the cost of author charges low enough to maximise the chances of NAR's long term ... memberships would keep the cost of author charges low enough to maximise the chances of NAR's long term success as an Open Access journal." "I b...Open Access journals proven to compete on quality
...ance of its titles answers spurious accusations of low quality of Open Access journals by some traditional subscriptions publishers. Jan Velterop, BioMed Central's Publisher, said: "It is becoming ever clearer that BioMed Central's Open Access journals, once beyond their early infancy, are recognised as ...Jefferson researchers develop microchip to track genetic signature of cancer and normal tissue
...el, however, the RNA level of the targets would be low and the expression of the oncogene would be low," he says. Conversely, "knocking out" the miR gene would mean the expression of the oncogene would be high. "MiRNAs are a new mechanism involved in malignant transformation," he says. "I think it will ...AAAS 2004 salary survey: Despite long hours and low pay, life scientists love their work
...e academia it's about $88,000. Postdocs are at the low end, averaging $39,000, while physicians bring home approximately $170,000. Seventy percent of scientists in universities and other doctoral-granting institutions claim they are either "extremely" or "very" satisfied. Self-employed people als...New multidisciplinary research tops chemists' meeting Aug. 22-26
...sical processes hidden at higher temperatures. How low can they go? A chilling millionth of a degree Kelvin. The ACS Division of Physical Chemistry is the symposium host. On Wednesday, Aug. 25, researchers will discuss new developments and future directions for the burgeoning field of metabonomics the s...Lupus Research Institute awards $3 million in novel research grants to further new science in lupus
...me lupus patients, which promotes the oxidation of low density fats (OxLDL), leading to atherosclerosis. The LRI grant will allow Dr. Hahn to explore the abnormalities in HDL in lupus patients and determine their correlations with disease manifestations. Her research may lead to a new test for pro-infl...Study finds first evidence COX-2 enzymes can regulate DNA damage
...that regular use of aspirin led to an unexpectedly low incidence of colon cancer. But all was not rosy. In addition to inhibiting the production of COX-2, aspirin also inhibits production of COX-1. These COX-1 enzymes make prostaglandins, regulatory molecules important for, among other things, preventin...Calcium supplements associated with decreased risk of large bowel polyps
...re was some evidence that a diet high in fiber and low in fat increased the preventive effect of calcium, but these results were not statistically definitive. These findings "suggest that total calcium intakes above 1200 mg are necessary, and perhaps that high dietary fiber and modest dietary fat are req...Stanford researchers go from heaven to Earth in 'lifeguard' test
...ile. It's an environment that combines low-oxygen, low atmospheric pressure and high ultraviolet radiation. Once at the peak, the team leader tested the equipment in a yet more rigorous environment by jumping into a lake. At about 19,200 feet, it's one of the planet's highest. Kovacs also carried out the...Altered protein involved in a novel link to Alzheimer's disease
...on of tau, and brain atrophy/loss of neurons. Only low levels of the protein P25 are found in healthy brains. However, in the brains of people with Alzheimer's, the p25 proteins are significantly increased. P25 is actually a fragment of another protein, and can be formed when a stroke or some oth...Ecosystem bounces back from hurricanes
...he mass-migrating crabs. "We feel the historically low abundances of blue crabs in 2000 and 2001 are a direct result of the interactions between floodwaters and overfishing," Eggleston said. "The blue crabs migrated en masse, which concentrated them and made them more vulnerable to fishing." Another piec...Genetic modification in mice lowers cholesterol and homocysteine by half
... other animals provide lipids for high density and low density lipoproteins (HDL and LDL) did not appear to suffer any ill effects. But animals from both groups had markedly lower levels of cholesterol in their blood stream. Alteration of one of the pathways also lowered blood levels of homocysteine by 5...Changes to insect-seeking calls of horseshoe bats may drive new species formation
...e-eared horseshoe bat can hunt and feed upon. The low harmonic frequency used by large-sized horseshoe bats, for instance, is perfect for detecting large insects over long distances yet completely misses small insects, which are easily scoped out by small-sized horseshoe bats using the higher harmonic f...Volcanic soils yield new clues about the emergence of powerful chiefdoms in Hawaii
...tely high within the agricultural system, but very low in the higher elevations above it," Vitousek said. According to the researchers, these results provide strong evidence that the early inhabitants of Kohala had discovered a "sweet spot" of high soil fertility a swath of land, rich in phosphorus and ......d for parasite development, H. subflexa has a very low level of parasites compared with other caterpillars. By adapting to a fruit that no other caterpillar wants, H. subflexa has found a niche where life is good. An uncontested food supply, a way to eat the fruit without calling up the pl...