Other highlights in the February 18 issue of JNCI
...ous 5 years. They found that the risk of Hodgkin's lymphoma was lower with regular aspirin use (2 or more tabl...there was no association between risk of Hodgkin's lymphoma and use of other non-aspirin NSAIDs, but the risk was higher with regular acetaminophen use. "If as...Pioneer in the genetics of programmed cell death honored
...llular homeostasis." Korsmeyer's experiments on lymphoma cell lines and genetic mouse models established that the oncogene BCL-2 plays a primary role in blocking cell death. As a result, BCL-2 became the archetype of a new category of oncogenes: regulators of cell death. Recently, in the last two years, ...Scientists making advances in cancer prevention, detection and treatment to receive awards
...eld has done pioneering work in adult leukemia and lymphoma over three decades. Her groundbreaking contributions have dramatically improved patient treatment, especially through her demonstration that older patients can be cured with appropriate therapy. The award's namesake was an honorary member and past ...Premier international meeting provides latest news and issues in blood disorders
...atology, covering topics ranging from leukemia and lymphoma to thrombosis and stem cells. "The ASH annual meeting is the premier event for academic and practicing hematologists throughout the world, providing a unique forum for hematologists to learn about scientific and clinical advances in the area o...Technique kills cancerous cells, leaves healthy cells intact
...re the compound was simply exposed to leukemia and lymphoma cells and healthy white blood cells from mice. "It...viding T-cells while almost completely killing the lymphoma and leukemia cells." Such results are desirable, because many current human therapeutic approaches r...Three molecular-targeted compounds show promise against cancers
...s such as renal cell, colorectal and non-Hodgkin's lymphoma of three compounds. The studies were presented today at the International Conference on Molecular Targets and Cancer Therapeutics organized by the American Association of Cancer Research (AACR), National Cancer Institute (NCI) and European Organizati...New therapies under development promise improved relief for Non-Hodgkins Lymphoma cancer patients
...etter relief for patients. "The need for improved lymphoma treatments has by no means disappeared and a large...fronted by high production costs. "Most of the new lymphoma therapies under development are monoclonal antibodies," says Hester. "These antibodies are high-pric...OHSU researchers discover molecular signaling system controlling aspects of embryonic development
... a cell-surface receptor protein called anaplastic lymphoma kinase (Alk) in the late 1990s. All that was known about human Alk was that it could cause lymphoma if abnormally regulated; its normal function had not been determined. After initial publication of ...University of Pittsburgh scientist honored for major accomplishment in cancer research
... other immune disorders including a type of B-cell lymphoma and Castleman's disease, a noncancerous but severe disorder characterized by enlargement of the lymph nodes. Dr. Chang will share the $125,000 Marks Prize with two other scientists under the age of 45 who have made significant contributions to the b...Young cancer researchers honored
...ection with KSHV can also lead to a type of B-cell lymphoma and Castleman's disease, a noncancerous but severe disorder characterized by enlargement of the lymph nodes. For decades, Kaposi's sarcoma was believed to be caused by an infectious agent. But until Dr. Chang and her husband and collaborator, Patrick...Study finds potential way to improve cancer immunotherapy
...ximab (Rituxan) for certain types of non-Hodgkin's lymphoma and trastuzumab (Herceptin) for breast cancer. Pe...rd killing the cancer," Weiner said. Non-Hodgkin's lymphoma is cancer of the lymphatic system, which normally fights infection. The lymphatic system includes ly...HAART therapy significantly prolongs survival in AIDS patients with central nervous system lymphoma
... AIDS patients with primary central nervous system lymphoma who receive the HAART "cocktail" therapy live much...ally, patients with primary central nervous system lymphoma have a very poor prognosis with a survival of only a few weeks to months after diagnosis," said Dr. ...Sequence of human chromosome 7 is fine-tuned and finished
...efit research in cystic fibrosis, deafness, B-cell lymphoma and other cancers, genes for which are found on chromosome 7. Also found there is the gene for P-glycoprotein, a protein that enables cancer cells to resist anticancer drugs. Other important genes found on chromosome 7 include those that help contro...Swedish researchers link endometriosis with increased risk of some cancers
...s it increased by about a third, for non-Hodgkin's lymphoma it increased by about a quarter and for brain tumo...evelop these tumours each year; for non-Hodgkins's lymphoma (12 cases a year amongst Swedish women) there would be another three cases, and for brain tumours (1...Journal announces scientific releases
...ally on blood disorders, ranging from leukemia and lymphoma to sickle cell to stem cell research. These will be made available free to the media at EurekAlert! Blood, the Journal of the American Society of Hematology, is the most cited peer-reviewed publication in the field. All articles undergo rigorous ...DNA arrays diagnose, predict survival for Sezary syndrome cancer patients
...ity of 4,500 different genes in a leukemic form of lymphoma known as Sezary syndrome, researchers at The Wista... each year in the United States. "Cutaneous T-cell lymphoma is very treatable in its earlier stages, but very resistant to treatment later on," Showe says. "One...Scientists find fully differentiated blood cells remain able to switch identity
... this approach offers the potential for converting lymphoma cells that are resistant to treatment into more manageable forms of cancer. "We found that just two genes, EBF and Pax5, are turned off when B-cells are concerted into macrophages; Pax5 is a known oncogene implicated in the growth of B-cell lymphomas...University of Pittsburgh findings published in Science illustrate how KSHV causes cancer
...cted against KSHV-associated tumors often found in lymphoma and Castleman's disease, a rare disorder characterized by non-cancerous tumors that may develop in the lymph node tissue throughout the body....Model for common type of cancer developed by UCLA scientists
...lymphomas. Specifically, the three types of B-cell lymphoma that grew out of Teitell's animal model were Burkitt-like lymphoma, diffuse large B-cell lymphoma and follicular center cell lymphoma, all of which are classified as non-Hodgkin's lymphomas. Now the...Stanford researchers find cause, possible cure for gluten intolerance
...and to reduce the risk of developing osteoporosis, lymphoma or cancer of the small intestine, he added. In the laboratory, Shan simulated the digestive process, exposing gliadin todigestive enzymes in test tubes. She identified a protein fragment made up of 33 amino acids that was resistant to further digesti...