Researchers isolate key part of cells death signals
...led BCL-2, named for the disease it causes B-Cell lymphoma when it is overexpressed in white blood cells, allowing them to accumulate abnormally. BCL-2 performs much of its pro-survival function by binding and sequestering pro-death molecules, preventing them from transmitting a pro-death signal. Some pro- ...Rad50 and the maintenance of genome stability
...ed Rad50-mutant mice exhibited a predisposition to lymphoma development, which the researchers traced back to a general inability to maintain the integrity of their genome. Interestingly, though, the genomic instability found in these Rad50-mutant mice was not the result of a biochemically detectable decreas...Other highlights in the August 21 issue of JNCI
...associated Kaposi's sarcoma (KS) and non-Hodgkin's lymphoma (NHL) is going down, according to a study of U.S. ...in incidence of Kaposi's sarcoma and non-Hodgkin's lymphoma since the mid-1990s may reflect a drop in the number of individuals with AIDS and the introduction o...Technique to induce cancer cells to 'commit suicide' developed by Hebrew University scientists
... students of his are now adapting this strategy to lymphoma and leukemia. A start-up company, Algen Biopharmaceuticals, has been established by the Yissum Research Development Co. of the Hebrew University, together with Prof. Levitzki and investors, to further develop this technology. Prof. Levitzki cautione...18F-FDG PET predicts lymphoma treatment outcome
...survival in patients with aggressive non-Hodgkin's lymphoma (NHL) or Hodgkin's disease (HD) than PET scans con...ty, there will be an estimated 60,900 new cases of lymphoma in 2002, including 7,000 cases of Hodgkin's disease and 53,900 cases of non-Hodgkin's lymphoma. An ...Investigators use guilt-by-association strategy to track potential cancer causing genes
...ple potential cancer genes whose activation led to lymphoma in both groups of animals. Of most interest were insertion sites common to more than one p27-deficient mouse. With tens of thousands of genes in the mouse genome, insertions in a common site in multiple p27-deficient animals (with few or no insertion...New study shows passive cigarette smoke at least doubles risk of cancer in cats
...elationship between passive smoke and non-Hodgkins lymphoma in humans, which is similar to lymphoma in cats. "It has long been believed that the major cause of feline lymphoma was feline leukemia viru...Gene profiles predict survival
...ivity of as few as 17 genes can be used to predict lymphoma patients' response to treatment, scientists report... a sample of tissue. This study of the most common lymphoma in adults focused on more than 12,000 genes expressed by lymphoid tissue and found 17 that were stro...Stanford study finds potential shingles prevention in a childhood vaccine
... inactivated version of the chicken pox vaccine on lymphoma patients about to undergo a hematopoietic cell transplant to combat cancer. Because these patient's immune systems are weakened by the disease and its treatment, up to one third of them develop shingles within 12 months of their transplant. Using an ...Complex gene-swapping spawns a form of lymphoma
...2002 -- Researchers have identified how a form of lymphoma develops when large pieces of chromosomes swap loc...earrangements, or translocations, cause pro-B cell lymphoma in mice offer a fresh perspective on how cancers arise from an increased "dosage" of specific genes ...Other highlights in the May 1 issue of JNCI
... EBV-related infectious mononucleosis and Hodgkins lymphoma have been associated with high socioeconomic status. Researchers have speculated that factors related to socioeconomic status could explain or contribute to the association between these diseases. To indirectly determine if this is true, Henrik Hjalg...UM Cancer researchers test custom-made vaccine for non-Hodgkin's lymphoma
...g a custom-made vaccine for low-grade non-Hodgkins lymphoma that uses each patients own tumor cells to combat ...ncer. This type of low-grade follicular lymphoma has traditionally been highly treatable, but essentially incurable, says Aaron P. Rapoport, M.D., th...U-M scientists find new genetic marker for prostate cancer
...state, ovarian, breast, bladder, lung, renal cell, lymphoma and melanoma with the highest amounts present in colorectal and prostate cancer. Research on the genetic and molecular profile of prostate cancer using DNA microarray analysis is part of a major initiative underway in the U-Ms Comprehensive Cancer C...UT Southwestern researchers link human lymphomas to polio vaccine tainted with monkey virus
... (SV40) in the tumors of 43 percent of non-Hodgkin lymphoma patients. The virus, predominantly of the B-cell type, was present in 9 percent of Hodgkin lymphoma cases, a significantly lower rate. The percentage of SV40-positive findings among healthy subjects a...SV40 found in human lymphoma samples
...SV40) infection found in 42 percent of non-Hodgkin lymphoma samples could shed new light on the genesis of these blood cancers that have become more common over the past 30 years, said BaylorCollege of Medicine scientists in a report in the March 9 issue of The Lancet, a British scientific journal. About 55,0......orm of blood cancer called aggressive non-Hodgkins lymphoma (NHL). This according to pivotal study results highlighted today in the New England Journal of Medicine (NEJM). The journal details the two year results from the pivotal GELA study where it is estimated that patients treated with MabThera plus CHO...Research to be presented concerning Bexxar at the American Society of Hematology Annual Meeting
...of low-grade or transformed low-grade non-Hodgkins lymphoma (NHL) includes: Contact: Julie McQuain (212) 477-0472 Sunday, December 9, 2001 [1433] Acute and Delayed Hematologic Toxicities Associated with Bexxar Therapy Are Modest: Overall Experience in Patients with Low-Grade and Transformed Low-Grade NHL. D...Durable responses reported with Bexxar
...f low-grade or transformed low-grade non-Hodgkin's lymphoma (NHL), provides durable, long-term responses when .... Kaminski. Non-Hodgkin's Lymphoma Non-Hodgkin's lymphoma is a form of cancer that affects the blood, bone marrow and lymphatic tissues. NHL currently is the...New global survey demonstrates an increasing demand for new treatments for non-Hodgkin's Lymphoma
...he number of patients suffering from non-Hodgkin's lymphoma (NHL). The average reported increase in cases of NHL, a form of cancer of the immune system, was 13%. The survey also showed that 9 out of 10 physicians (91%) who prescribe MabThera (rituximab) for the treatment of this increasingly common form of...More chance of a cure for patients with common and aggressive form of blood cancer
...erapy in the treatment of aggressive non-Hodgkin's lymphoma (NHL) Orlando, Florida, 10 December 2001 - Patie...urvival for patients with aggressive non-Hodgkin's lymphoma (NHL), a rapidly fatal form of the cancer. This is a real breakthrough for NHL sufferers around th...