EMBO Gold Medal 2004 goes to Spanish scientist
... of the telomeres; and demonstration that telomere maintenance requires both telomerase activity and homologous recombination. Since 1997, Mara Blasco has published more than 65 papers on telomere research in publications such as Cell, Nature Genetics, Molecular and Cellular Biology, and The EMBO Journal. The sc...HHMI, NIBIB/NIH to invest up to $35 million in interdisciplinary Ph.D. programs
... model to support the initiation, development, and maintenance of new graduate programs to provide upcoming biomedical scientists with the cross-disciplinary knowledge and skills they will need. "This groundbreaking partnership between the NIBIB and HHMI will produce researchers who are skilled in biomedical...University of Alberta researcher looks for clues to mysterious disease
...ting the basic mechanisms of chromosome structural maintenance involving ATM, allowing us to study how ATM works in a meaningful developmental context." Although a cure seems to be a long way off, using this system to understand more about how ATM works will offer more clues to treating the disease, said ...$7.5 Million grant to Yale researchers for role of viruses in cancer
... the role of small viral RNAs in the induction and maintenance of tumors. Many RNAs that she studies were first identified in the collaboration with Miller supported by this grant. Joann Sweasy , associate professor of Therapeutic Radiology and Genetics , investigates the role of mutant DNA polymerase...Environmental costs of home construction lower with wise choice, reuse of building materials
...hrough improved products, construction designs and maintenance practices. The Consortium for Research on Renewable Industrial Materials has started a new $1 million research project that expands the current effort to include all U.S. wood-product supply regions, other non-structural wood products and additiona...Progress in breast cancer progression
...or an essential role of NF-kB in the induction and maintenance of the transition that cancer cells undergo to become invasive and mark the NF-kB pathway as a potential anti-metastatic therapeutic target. ...JCI table of contents, 16 August, 2004
...or an essential role of NF-kB in the induction and maintenance of the transition that cancer cells undergo to become invasive and mark the NF-kB pathway as a potential anti-metastatic therapeutic target. TITLE: NF-kB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer pr...Good bacteria trigger proteins to protect the gut
... MyD88-deficient mice, implicating TLRs in overall maintenance of the tissue. The animals' intestines were partic...e, recovery from radiation-induced damage requires maintenance and repair processes that, the researchers found, depend on TLRs. They found that in response to DSS...New lower-cost assay system equivalent to flow cytometry for accurate CD4+/CD8+ cell counts
...duces the running costs of using the system. Daily maintenance is minimal just a fast and easy 5 minute clean and shutdown procedure performed at the end of each day. "The Guava EasyCD4 and EasyCD8 enable easy monitoring of T cell health in HIV-infected patients, using a benchtop system that is reliable and rob...In the obese, metabolic adaptations post-weight loss lead to regaining of shed pounds
...ustments that occur in response to weight loss and maintenance that make successful weight maintenance a challenging prospect. The authors of the study, "Metabolic Adjustments with the Development, Tre...Endometriosis: Could angiostatic therapy be the new treatment of the future?
...ns growing and whether it could interfere with the maintenance and growth of existing lesions. They used four ang... However, it also interferes effectively with the maintenance and growth of endometriotic lesions, and thus may be a promising way of preventing the recurrence of...Gene mutation causes progressive changes to cell structure in children with Progeria
...ghlights the importance of the Lamin A gene in the maintenance of cell structure and function." In April 2003, a team of researchers assembled by The Progeria Research Foundation (PRF), and including the National Human Genome Research Institute (NHGRI), one of the 27 institutes and centers that make up the Natio...Obesity and hypertension: Two epidemics or one?
...ugs in short-term weight loss and long-term weight maintenance has been documented in randomized controlled trials but attrition rates are high. 9. Prevention of obesity hypertension. The average weight gain of the population in the United States is estimated to be approximately two pounds per year and weight ...Atherosclerosis treatment needs to go with the flow
...nting only the main branch for optimal healing and maintenance of open vasculature....JCI table of contents, 1 June 2004
...nting only the main branch for optimal healing and maintenance of open vasculature. TITLE: Dynamic flow alterations dictate leukocyte adhesion and response to endovascular interventions AUTHOR CONTACT: Yoram Richter Tel Aviv, Israel Phone: 972-3-767-9000; Fax: 972-3-647-5351; E-mail: yrichter@biorest.co.il ....Indoor mold, building dampness linked to respiratory problems and require better prevention
...blems stem from building designs, construction and maintenance practices, and building materials in which wetness...eers, building contractors, facility managers, and maintenance staff do not always apply this knowledge, the report says. Training curricula on why dampness probl...JCI table of contents, 17 May 2004
...ts suggest the involvement of E2F1 and E2F2 in the maintenance of differentiated cells in the pancreas and support their distinct role as transcriptional repressors that cannot be compensated for by other members of the gene family. TITLE: Diabetes and exocrine pancreatic insufficiency in E2F1/E2F2 double-mutant...New guidelines show significant benefits of FUZEON for wide range of pre-treated HIV/AIDS patients
...aining programmes yield significant returns in the maintenance of adherence, patient confidence, and in the benefit of FUZEON therapy "FUZEON is an important treatment for the increasing number of patients with HIV drug resistance. By providing clear advice on timing of FUZEON initiation and patient support du...Insulin-producing pancreatic cells are replenished by duplication
... used to trace the origin of cells involved in the maintenance and repair of other types of tissue. Melton and his colleagues are already using the technique to determine the origin of new cells in lung tissue. And it should be possible to apply the technique to understand the origin of cancer cells in tumors or...New research suggests therapeutic approach for autoimmune diseases
...," explains Dr. Roopenian. "The consequence is the maintenance of dangerously high levels of autoantibodies." To test this idea, Dr. Roopenian used mice that normally develop arthritis caused by autoantibodies. His team shows that the elimination or blocking of FcRn resulted in the reduction of autoantibodies a...