JCI Table of Contents, November 3, 2003
...amide biosynthesis through 4-desaturation and that maintenance of ceramide composition is important in epithelial barrier function. TITLE : Alteration of the 4-sphingenine scaffolds of ceramides in keratinocyte-specific Arnt-deficient mice affects skin barrier function AUTHOR CONTACT : Junji Takeda Osaka Uni...U-M scientists find genetic 'fountain of youth' for adult stem cells
...lls to divide throughout life is necessary for the maintenance of adult tissues. Most cells in the body are programmed to stop dividing after a limited number of cell divisions, but adult stem cells and cancer cells have the ability to continue making identical copies of themselves for long periods of time, if n...NSF awards four-year, $3.9 million grant to plant biology team led by University of Georgia
...lls that are lost during growth. Establishment and maintenance of these structurally and functionally distinct zones of the SAM is achieved by differential expression patterns and interactions of thousands of plant genes. New technologies now give scientists the ability to identify and analyze genes required fo...UCSF-led study raises doubts about marrow cell treatment for brain, heart
...esting that it might contribute to development and maintenance of some cell types, and could be one of the body's strategies for repairing damaged cells. "My hunch is that fusion might be a physiological mechanism that the body has devised to import DNA from blood cells into damaged cells in various tissues," s...NIEHS-funded researchers find low-level ozone increases respiratory risk of asthmatic children
... Sciences suggests that asthmatic children who use maintenance medication are particularly vulnerable to the effe...y more than 35 percent among asthmatic children on maintenance medication," said Brian Leaderer, Ph.D., the Susan Dwight Bliss Professor of Epidemiology at Yale Un...UCSD researchers find promising new avenues for treating infections
...ng phospholipids, which are needed for normal cell maintenance and repair. However, the researchers remain optimistic. "It is definitely a possibility that we can find chemicals that are specific for the toxin and won't affect mammalian cells," says Phillips. "We are currently working to determine more detaile...OHSU scientists uncover key protein for Fanconi anemia, cancer susceptibility
...ion of the FA protein network, particularly in the maintenance of a stable genome, the "hard drive" of the cell where genetic information is stored. Fanconi anemia is a rare, genetic cancer-susceptibility syndrome. When both parents carry a defective or mutated FA gene, children are at increased risk of developi...State of Amazonas safeguards world's richest biodiversity with six new protected areas
...r the protection of fresh-water ecosystems and the maintenance of populations of species that are threatened in other parts of the country." The park is home to some 250 villagers that live along the banks of the Juta River in abject poverty. It was named after the Cujubim bird (Pipile cumanensis) that is though...Natural fat compound may be basis for new class of drugs targeting obesity
...A, but may contribute to the overall stability and maintenance of our feeding system," Piomelli said. Piomelli believes OEA is attractive for drug development because it is a fatty acid naturally produced in the body and could be safer than current drugs when used as a long-term therapy for obesity. "There are m......roliferate. The study lends great insight into the maintenance of memory cells and their persistence at the site of chronic inflammatory disease. TITLE: CD28 costimulation independence of target organ versus circulating memory antigen-specific CD4+ T cells AUTHOR CONTACT: Andrew P. Fontenot University of Colorad...Researchers try to determine why cancer cells don't commit suicide
...hought to be a requirement for the development and maintenance of cancer. However, the specific defects that lead to cancer cell resistance to cell death are poorly understood," said Andrew Thorburn, D. Phil, and principal investigator of the studies. The Medical Center has received three Department of Defense...White shark attack shows they're not man-eaters
...sually warm for a fish at 75 degrees F.). It's the maintenance of that high core temperature that makes him think great whites need the energy contained in seal fat and don't intend to kill humans. "The fat in seals' outer coats makes up half their body weight and has twice the calories of muscle. Seals and sea ...Weather extremes shed light on prairie's past and environment's future
...ion rates played a major role in the formation and maintenance of the western boundary (Tulsa to Fargo) separating the short grasses of the plains and the tall grass triangle. The tall grasses needed enough warm-weather precipitation to produce the higher evapotranspiration rate, the researchers found. The expe...JCI Table of Contents, 15 August 2003
...in a central pathway for cell proliferation and/or maintenance of the transformed state. While much more analysis is needed to decode the molecular mechanisms of Cripto function, the work now provides a glimmer of understanding as to the functions of this enigmatic protein in tumorigenesis". TITLE: Antibody blo...Search beneath lawns provides insight into backyard biodiversity
Lawn mowing and maintenance can make homeowners' summer free time disappear, b...ryomorpha collembola were most abundant in the low maintenance lawns and reduced in the high maintenance lawns. "These Collembola live at the soil thatch interfac...Diet researcher asks how now lemur chow?
... going to have reproductive problems." And captive maintenance has become critical to zoos, she said. "It used to be that when a zoo wanted to replenish its collection, it would just go capture more animals and bring them back. But that doesn't happen anymore. So, successful captive breeding is very important, ...Lead-based paint is poisoning albatross chicks at Midway Atoll National Wildlife Refuge
... is better lead-hazard control, including building maintenance and clean-up of the site." Lead-poisoned chicks are common around the buildings on the island, Finkelstein said. Many chicks with lead poisoning don't have droopwing, but likely suffer from other forms of toxicity that lower their chances of survival...Making sense of bacterial biodiversity
...rd understanding the processes responsible for the maintenance of bacterial biodiversity....Scientists find potential stem cells in amniotic fluid a new source?
... is no doubt as to the importance of Oct-4 for the maintenance of stem cells," said Professor Hengstschlger. "Each mammalian pluripotent stem cell line expresses Oct-4, which rapidly disappears when the cells differentiate." Further tests on the nucleus confirmed that the correct molecule had been analys......been too small and fragmented for effective forest maintenance and regeneration. A minimum level of landscape connectivity is necessary to promote key ecological processes," he said. Conservationists have recommended a regional strategy that includes forest restoration and the establishment of ecological corrido...