Researchers uncover secrets of immune system's munitions factory
...PA's involvement makes biological sense. The other major discovery, said Alt, was that for AID to interact ..., we can begin to address this problem, which is a major question in the field."...Images reveal how rotavirus - leading cause of diarrhea - enters cells
...blished in the August 26th edition of Nature, is a major advance in the understanding of how viruses cause infection, and illustrates how vaccine development can be made "smarter" by probing the physical architecture of viruses and finding the minimum parts needed to prime the immune system, without having...Computer database being developed at Temple will allow for better inventory of chemicals
... chemicals being used in laboratories throughout a major research institution like Temple University can be a daunting task, often requiring untold lab visits and countless man-hours to complete. But now, thanks to virologist Jay Rappaport, Ph.D., an AIDS researcher in Temples Center for Neurovirology ...Visiting African scientists collaborate with MBL scientists on infectious diseases
... sickness, a fatal disease that has reemerged as a major health problem in sub-Saharan Africa. Gustave Simo, from Cameroon, will be at the MBL from now through mid-September. Henrietta Awobobe, from Nigeria, will arrive mid-September to spend three months in the GID laboratory. The Ellison Visiting Schola...Regular physical activity really does boost immune system in older men
...ly active and some sedentary. Using KLH overcame a major problem in many earlier age vs. exercise studies which typically utilized in vitro tests or vaccine or recall antigens to elicit an immune response. In the first stage, all subjects were "immunized" with KLH with blood collected on day one and then ...Trojan Horses, xenon imaging and remote controlled genes
... researchers wielding them. Currently, one of the major obstacles to research is actually getting inside of cells and tissue to see what is going on as it happens. At the University of Pennsylvania, researchers are caging molecules xenon, gene-blocking strands of antisense DNA and even therapeutics to ...JGI announces community sequencing program portfolio
...-sea." Crenarchaeota are members of the Archaea, a major branch of life that includes many microbial extremophiles--microbes that can live at extreme temperature, salinity, or high acidity. Additional CSP DNA sequencing projects in the pipeline include: The complex bacterial community that lives under th...Engineering endurance: The future of the Olympics?
...s suspected that a nuclear receptor called PPAR--a major regulator of fat burning in fat tissue that is also prevalent in skeletal muscle--might be involved and genetically engineered mice to express an activated form of the PPAR protein in skeletal muscle. The transgenic mice showed much higher levels of ...Carnegie Mellon scientists reveal ways of studying, resolving PCB contamination in US rivers
... river water (and hence sediment) temperature is a major driver of PCB release from sediments. Microbes appear to be one of the major culprits, releasing PCB-containing gas bubbles that percolate through river sediments. Microbes, as ...Anticancer drug zebularine specifically targets tumor cells
...enes is a critical part of the cancer process is a major conceptual advance in this field," Jones says. "Realizing that, it becomes very important to find keys to unlock those silenced genes." In the Cancer Cell study, Jones, Cheng and graduate student Christine Yoo--along with colleagues from the National...2nd media alert First Scientific Conference on Childhood Leukaemia
...re attending and presenting new research data. Two major concerns prompting the charity to convene the conference are: Incidence in under 5s is rising and we don't why It is now clear that although survival rates have risen dramatically since the 1960s, survivors face higher risks of developing anothe...Congress to fund Sequim-based coastal security research effort
...t two-thirds of the nation's population, as wellas major industries, scenic and economically important natural resources, and some of the world's busiest maritime traffic. But America's coastal environment may be a target for terrorist activities as well.In recent testimony to Congress, Arizona Senator Jon...Genetically-engineered 'marathon mouse' keeps on running
...mice with enhanced PPAR-delta activity, they saw a major transformation in skeletal muscle fibers. The mice showed a major enhancement of so-called "slow-twitch" muscle fibers and a decrease in "fast-twitch" muscle fibers. ...Penn scientists identify novel pathway in aneurysms
...l, consisting of fatty deposits that progress into major plaques that eventually break off from the inner lining and lead to heart attacks. "The danger of aneurysms is that we don't normally carry out routine screening for their detection and by the time they are found most of the progressive damage may ha...Muscles are smarter than you think
...t acidity, through a build up of lactic acid, is a major cause of muscle fatigue. Professors George Stephenson and Graham Lamb of La Trobe's Muscle Research Laboratory and Mr Thomas Pedersen and Professor Ole Nielsen from the University of Aarhus, presented their findings to the scientific world in Science...Restoring sweetgrass to the South Carolina lowcountry
...ts, now highly prized as works of art, represent a major source of income for the community. Sweetgrass (Mu...tgrass habitat, but residential development is the major cause," says Burke. "The coastal savannah habitat has disappeared from much of this land, and areas ...Study suggests cell-cycle triggers might be cancer drug targets
...The blood system issue aside, the results remove a major theoretical objection to developing drugs that would inhibit, or block, overactivity of cyclin D proteins, according to the study's authors. Excess cyclin D production has been seen in tumors of the breast, head and neck and stomach, and in some bloo...Researchers report new gene test for isolated cleft lip and palate
...statistician at the University of Pittsburgh and a major contributing author on the paper. "What we found is that a particular haplotype is overtransmitted in some families with isolated clefts, suggesting a predictive association with the birth defect, and this was true in the populations that we analyze...NIH roadmap for biomedical research focus of chemists at American Chemical Society meeting
...merous scientific journals and databases, convenes major research conferences and provides educational, science policy and career programs in chemistry. Its main offices are in Washington, D.C., and Columbus, Ohio....Nucleic acid-amplification testing further safeguards nation's blood supply
...ctiveness of the NAT assay system nationally. All major blood donation laboratories in the United States participated, accounting for more than 98 percent of tested blood donations. Many organizations collaborated on the research, including the American Red Cross, Blood Systems Research Institute, America...