Tag: "mammalian" at biology news

Emory University Scientists Demonstrate New Pathway For Genetic Mutations In Everyday Cell Life

...ributing to malignant transformation inthe case of mammalian cells." "The findings also have implications for a number of other things,including age-related cell death in cells that do not normally divide -- likeneurons, for example, which could lead to neurodegenerative diseases." "This exp...

First North Americans Had Chance To Be Avid Birders

...sion is supported by a plethora of contemporaneous mammalian remainsfrom the site, including those of mammoth, bison, horse, dall sheep, caribou,moose, wapiti, saiga antelope, lion, bear, cougar and wolf. The Bluefish caves site was discovered in 1975 and excavated between 1978 and1987 by a research team led b...

UCSF Scientists Report On A Transcription Factor That Could Stimulate Heart Cells To Repair Damage Caused By Heart Attacks Or Birth Defects

...pair damaged tissueafter an injury. In many other mammalian organs, cells replenish themselves and repair damage byre-entering the cell cycle. In this cycle, the cell stays for some time in aphase called G1 as it prepares to duplicate its content of DNA. Next it enters aphase called S for synthesis, when the ...

Trash From Crop-Processing Plant Harvested For Disease-Fighting Agents

...ssing plants. Initial laboratory tests on cultured mammalian and human cells indicate anethanol extract of soybean molassesrepresses the ability of at least one dietary carcinogen to damage the DNA ofnormal cells, the researchers report. A report is being published in the May issue of Agricultural Research Mag...

'Dual Control' Strategy Assures Accurate Cellular Marching Orders, But A Pathogenic Microbe Can Hijack The System

...late the multiple signals that are normallyused in mammalian cells to activate Enabled, but does so with a single, tighterbinding molecule," said Kenneth E. Prehoda, Ph.D., postdoctoral fellow in Lim'slaboratory and lead author on the study. "So, while normal cell movements aredelicate and highly regulated, Li...

UW scientists find a gene that controls organ shape

...at will," she said. "The second is that one of the mammalian counterparts ofthis organ-controlling protein may be involved in the spread of cancer cells." The grail of growing human organs for transplant in a laboratory dish is still adistant prospect. But with the new discovery of an organ-shaping protein, an...

Duke researchers discover protein that can alert immune system to fight cancer

...seevolutionarily ancient proteins are found in all mammalian cells and haverelatives in organisms as simple as bacteria and yeast. But calreticulin can perform another vital function, the researchersdiscovered. Through experiments in mice, scientists found it can act as aninformant to the immune syste...

Two-for-one special: industrial enzymes and food

... much safer and cheaper thanusing donated blood or mammalian cells to treathemophiliacs or wounds. See related news release at /www.pnl.gov/news/news.htm...

Maybe you can get blood from a turnip after all

... human blood plasma or by painstakinglycultivating mammalian cells. But treatmentsderived from human or animal ...cific Northwest. "And,unlike human blood donors or mammalian cells, plants provide a stable productionsource and yield much higher amounts of thedesired blood fa...

Fred Hutchinson Cancer Research Center researcher one of five awarded $1 million distinguished young scholars grant

... Dr. Frydman's researchinto protein folding inside mammalian cells is viewed as some of the mostinnovative in the chaperone/protein folding arena. Partho Ghosh, Ph.D., University of California, San Diego Dr. Ghosh is a leading investigator in structural biology and a noted expert inprotein crystallography and...

Scientists find first molecule that guides nerve cells through the brain

...y, the Washington Universityresearchers engineered mammalian cells that produced and secreted RoboN, theextracellular fragment of Robo. Then they used the RoboN to prevent Slit frominteracting with the normal Robo receptor. They placed pieces of septum on top of the kidney cells and cultured them withpieces of...

Researchers find missing spring in circadian clock of mammals

... up to now a large gap in our understanding of the mammalian clock. Someaspects of the mechanism are the same b...egative feedback loop in the inner workings of the mammalian clock.One is that its role could never have been predicted based on the structure ofthe protein itse...

Jurassic period mammal teeth found; prevailing theories challenged

...theisland of Madagascar, evidence that some of our mammalian ancestors roamed theEarth at exactly the same time...ime,how extremely little we still know about early mammalian evolution, particularlyfrom the Southern supercontinent of Gondwana." -- David W. Krause (Krause has...

Bubonic plague kills by cutting off cellular communication

...lles heel --- one family ofmolecules used by every mammalian cell to transmit signals involved in theimmune res... that YopJ targets allmembers of the MKK family in mammalian cells, but not other proteins in the MAPKpathway. Additional experiments revealed that the targeted...

Study of fruit flies may yield new clues to colon cancer development

...derstand how different APC membersin fruit fly and mammalian cells might influence the cytoskeleton," theresearcher says. Additional studies will involve the crystal structure of betacatenin, recently solved at Stanford University. "That gives us a 3-dimensional picture of the protein, so we can ask ho...

Roundworms provide clues to human kidney disease

...roundworms are easier and faster to work with than mammalian cells,and the entire sequence of the C. elegans genetic code is already known."The advantage is that we can do a lot of experiments faster," Sternberg said."It would be exciting to find more genes that work with lov-1 in the wormbecause those gen...

Common parasite overturns traditional beliefs about the evolution and role of hemoglobin

...moglobin is a linkbetween bacterial hemoglobin and mammalian hemoglobin," said WashingtonUniversity cell biologist Dena Minning, who, along with Duke's Andrew Gow, areco-first authors of the paper. "Hemoglobin in bacteria is used as an enzyme to destroy NO -- the'primordial gas' which evolved before th...

Eating soy can lead to dramatic declines in cholesterol, Wake Forest study shows

...their many chemical and biological similarities to mammalian estrogen," he said. Crouse said that while the cholesterol lowering properties of soy havebeen widely accepted, "the active ingredient had not been previously beenidentified." Speculation previously has ranged from the soy protein itself to ...

Researchers discover hemoglobin's enzymatic nature

...f it's on the other side of thepocket, as it is in mammalian hemoglobin, nitric oxide acts as a regulator ofoxy...asEarth's atmosphere began to contain more oxygen, mammalian hemoglobin evolvedthe ability to carry oxygen molecules to tissues and cart away the waste gascarbon...

New evidence pushes back age of sex-determining chromosomes

...ut there have been four times in thehistory of the mammalian sex chromosomes over the last 300 million years whenthe dam was opened and a bunch of genes flowed down the evolutionary stream.Since these dam openings were so widely separated in time, the groups of geneshave gone different distances down stream." ...

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