U-M scientists find new genetic marker for prostate cancer
...ese genes cause prostate cancer, but they can be a marker or indicator of prostate cancer for diagnostic or ...-M researchers say AMACR could act as a diagnostic marker for other types of cancer, too. When Rubin and Chinnaiyan surveyed cells from different types of can...Other highlights in the April 3 issue of JNCI
...s have used gene expression profiles to identify a marker of colon cancer progression through a method calle...xpression profile and that osteopontin is a useful marker of tumor progression in colon cancer. Also in the April 3 JNCI: Effects of depsipeptide in lung ...International rice genome project progressing ahead of schedule
...lso donated a Simple Sequence Repeat (SSR) genetic marker to the Better Bean Initiative to help further the Better Bean Initiatives goal of developing soybean lower in saturated fats. Other activities to share genetic data and specific technologies to help farmers are listed in the attached Backgrounder....Scientists trace recently found genes to the evolution of big brains
...ng oligodendrocytes. There is not currently a good marker for this kind of tumor, called an oligodendroglioma, but it is important to identify it since it can usually be treated effectively, explains Peter Black, MD, a neurosurgeon at Brigham and Womens Hospital who was involved in the previous work that le......ene that codes for a transposase flanked by unique marker sequences. When the enzyme is produced, it homes i...ntaining the gene to be introduced, flanked by the marker sequences, the other containing the gene for the P-element transposase. Trillions of copies of the...Other highlights in the March 20 issue of JNCI
...tes, which became highly melanized and expressed a marker of senescence. Restoring Arf expression did not affect senescence, but it increased cell death. The authors conclude that mouse melanocyte senescence requires both copies of Ink4a-Arf and depends more on p16 than on Arf function. Furthermore, mutatio...Researchers find evidence of genetic susceptibility
...e same form of AN, the linkage analysis pointed to marker D1S3721 on chromosome 1p, and additional genotyping provided evidence for the AN-susceptibility gene on chromosome 1p, said Dr. Berrettini. Currently, these collaborative researchers are looking for people with restricting-type AN who also have two p...Study suggests gum disease, cardiovascular disease link common phenomenon in developed countries
...d moderate to high levels of C-reactive protein, a marker for inflammatory activity associated with bacterial infection and the development of atherosclerosis. "We weren't surprised to find periodontal bacteria in the carotid arteries of this German cohort, but we expected some variation from those found i...Study boosts suspected link between mothers gum disease and both premature birth, low birth weight
...s not just that periodontal disease is a surrogate marker for poor oral hygiene or other socioeconomic factors just sort of jumbled together, the scientist said. The fact that were finding specific organisms that can cause growth and delivery problems opens up a whole new avenue for preventive care....Living in large groups could give you a better memory
...d the birds with a radioactive form of thymidine-a marker to track new neurons-and placed the birds in three different settings: either alone, with another bird of the opposite sex, or in a large group of about 45 other birds. After 40 days the researchers examined three specific regions of the birds' brain...The body's production of melatonin may be the reason why the elderly can't get a good night's sleep
...etween sleep-wake timing and the timing of another marker of circadian phase. The timing of the plasma melatonin rhythm is considered to be a more accurate marker of the status of the circadian timing system than that of core body temperature because it is less a...Tracing the neural circuitry of second sight
...ich each melanopsin-expressing cell also carried a marker gene called tau-lacZ, whose coded protein could be selectively stained. This protein was capable of traveling down the axons of the ganglion cells, revealing their targets. "The labeling was just beautiful," said Yau. "It showed that the axonal proje...Discovery of bacterial 'touch sensor' could lead to biofilm treatments
...ted a strain of bacteria with an easily detectable marker attached to the genes they wanted to study. Whenever the bacteria used those genes, the marker became visible. Otto exposed a vial of bacteria to tiny glass beads, which triggered the attachment ...Stool test for colon cancer reported by Kimmel Cancer Center at Johns Hopkins
...d technology to detect and highlight a key genetic marker of the disease, are reported in the January 31, 20...s team has always expected this early colon cancer marker was present in cells shed into stool, it required several years of additional research to develop th...A 2,000 year-old technique may hold the key to acupuncture's therapeutic effect
...of the body were identified and marked with a skin marker (16 acupuncture points total). Acupuncture points were identified according to traditional methods. Approximate position was determined in relation to anatomic landmarks (e.g., bones, tendons) and proportional measurements (e.g., fraction of the dist...UCLA researchers invent first technique to image Alzheimer's onset
... than 65. UCLA researchers combined a new chemical marker called FDDNP with positron emission tomography (PE...sease. This is a major gain." "Combining the FDDNP marker with PET scans will enable us to better screen participants for clinical trials and produce more acc......monoxide is the culprit because it could be just a marker for something else in tailpipe exhaust, said Gary Shaw of the California Birth Defects Monitoring Program and a co-author of the study. The fact that certain heart defects are turning up in the second month of pregnancy when hearts are being formed s...Two cholesterol-lowering statin drugs reduce another marker of coronary-artery disease
...at all three statins lowered a relatively new risk marker for cardiovascular disease called C-reactive protein in these patients.Other UT Southwestern researchers on the current study were Beverley Adams-Huet, faculty associate in internal medicine, and Dr. David Balis, assistant professor of internal medic...Hopkins researchers develop potential new screening test for prostate cancer
... in normal or benign prostate disease. "A genetic marker such as GSTP1 that occurs mostly in early-stage prostate cancers may improve the way we diagnose cancer in the future and help us to catch it early," says David Sidransky, M.D., professor of otolaryngology, oncology and urology and director of the re...Antibodies to liver stage associated with malaria resistance
...ated with it. "We recognize this as a very useful marker for predicting who might have resistance," says Duffy. "The key question is, what is the immune response that is mediating protection? It seems unlikely that the antibody response to LSA-1 alone is enough to prevent infection." "Other immune respon...