Alcohol abuse may increase susceptibility to HIV infection
...s assessed by expression of the cell cycle protein marker Ki67) in SIV-infected monkeys during the early sta... start dividing or proliferating. "The cell cycle marker Ki67 increases in cells that are proliferating," said Bagby, "so an increase in this protein indicat...Potential blood test for colon cancer risk
...r Center at Johns Hopkins. At present, the genetic marker blood tests are for research purposes only, Feinberg emphasized. "More efficient tests will take several more years at least to develop," said Feinberg, who with Hengmi Cui, Ph.D., and Marcia Cruz-Correa, M.D., Ph.D., led the study. "We also need to...Scientists' transgenic chicken aids embryo research
...blishing a line of chickens carrying that specific marker gene. Currently, the chick embryo is often used as a model to understand normal and abnormal embryo development. The new lines of transgenic chicken provide a new tool that can be employed in studies aimed at understanding birth defects such as limb...Scientists find 'stem cells' in human breast cancer
...ncers in mice. These cells all expressed a protein marker called CD44, in addition to having either very low levels or no levels of a marker called CD24. "As few as 100 to 200 of these tumor-inducing cells, isolated from eight of nine tumors...First population study of GM mosquitoes highlights difficulties facing malaria control technique
...ically modified mosquitoes quickly lose their test marker gene when they are bred with unmodified mosquitoes...er technology to insert a green or red fluorescent marker into four different lines of the mosquito Anopheles stephensi, the major carrier of malaria in India...Scientist pursues role of possible new cell type
...ment, rather than the relatively few tagged with a marker gene for the most recent study. "I would like to know, before I retire, what is the significance of these cells. I think it's tremendous," the 54-year-old scientist says of the VENT cells he has documented coming from the neural tube, which is known ...New strategies against disease revealed as scientists probe genes' tasks
... markers and therapeutic targets," Pevsner said. A marker for a disorder like autism may be particularly useful, according to Pevsner, so that it might be possible someday to use a blood test to determine whether someone is autistic. Eric Hoffman of Children's Hospital, in Washington D.C., said he is "pushi...... sleep. These finding represents the first genetic marker for SW. Citation source: Molecular Psychiatry 2003 Volume 8, number 1, pages 114-117. For further information on this work, please contact Dr. Mehdi Tafti, Belle-Ide, Biochemistry and Genetics, Chemin du Petit-Bel-Air 2, CH-1225 Chne-Bourg, Switzerla...Endothelial progenitor cells could serve as biological marker for cardiovascular disease
...how that endothelial progenitor cells are a useful marker for cardiovascular disease risk." Other members of the research team included Jonathan M. Hill, MRCP, Gloria Zalos, RN, Julian P.J. Halcox, MRCP, William H. Schenke, BA, Myron A. Waclawiw, PhD and Toren Finkel, MD, PhD, all of the NHLBI. The researc...Carnegie Mellon University receives NASA award to develop probes to detect life on Mars
...offer Lagerholm and Byron Ballou. The fluorescent marker technology proposed is based on the extensive expertise of the MBIC at Carnegie Mellon. Established 17 years ago with a multimillion dollar grant from the National Science Foundation, MBIC combines research on molecular and cellular sensors along wit......xt, an MRI scanner was used to measure levels of a marker inside neurons indicating the cell's health and abundance of synapses -- tiny junctions through which neurons communicate with each other. Again, subjects with one copy of "met" had lower levels of the marker, N-acetyl-aspartate (NAA), than matched ...A new animal study clarifies how different parts of the brain regulate sleep
...ount of prior waking and sleep, and may serve as a marker of sleep homeostasis. The enhancement of SWA by pr...r in the 12- to 15-Hz band in NREM sleep), another marker of human sleep regulation, also exhibited a specific topographic pattern. After prolonged waking in ...UW researchers discover gene mutation associated with a form of Charcot-Marie-Tooth disease
...y of the LITAF mutations could provide a molecular marker for the 1C form of Charcot-Marie Tooth. The researchers also hope the findings will lead to greater understanding of how the LITAF gene functions....Applied Biosystems announces SNPlex ultra high throughput genotyping system
... identify and validate drug targets and diagnostic marker candidates, and to discover and develop new therapeutics. Its Celera Discovery System TM online platform, marketed exclusively through the Applied Biosystems Knowledge Business, is an integrated source of information based on the human genome and o...Applied Biosystems and Immune Tolerance Network announce immunology research agreement
... identify and validate drug targets and diagnostic marker candidates, and to discover and develop new therapeutics. Its Celera Discovery System TM online platform, marketed exclusively through the Applied Biosystems Knowledge Business, is an integrated source of information based on the human genome and o...Serotonergic dysfunction doesnt cause suicide
...tor 2A (5HT2A receptor) density as a post-synaptic marker in the serotonergic system in postmortem brains of 10 suicide victims and 12 controls. In addition, to clarify the genetic involvement in serotonergic function, the authors examined whether the variations of the TPH gene could affect TPH protein lev...Search for cholesterol absorption genes narrows to two chromosome regions
...hayek chose to use plasma plant sterol levels as a marker of cholesterol absorption. Breeding mice in search of genes Next came the tricky part: genetic linkage analysis. In this gene-hunting technique, researchers crossbreed hundreds of mice in an attempt to link an observed trait to the genes that cause i...Promising biomarker for melanoma is identified
...searchers have identified a potential biomolecular marker for melanoma, the most serious form of skin cancer...verified independently by other groups before this marker could be used in the clinic," he says. The researchers tracked levels of HDM2 using an antibod...Mercury associated with risk of heart attack
...to mercury, just as adipose tissue fish oils are a marker of fatty fish intake. In addition, the correlation between mercury and fish oils indicates that fish is likely the main source of toenail mercury in these populations. The case-control study was conducted in eight European countries and Israel. Cases......respiratory function, or serum lactate, which is a marker for the severity of tissue injury. Current methods require obtaining blood samples and then sending those samples to a lab for analysis....