Norwegian study demonstrates targeted coxibs may prevent oral cancer
...chromosomes) in the DNA, indicating a genetic risk marker for cancer. The results are being presented for the first time at the Frankfurt conference. "We found that COX-2 expression was up regulated from healthy to premalignant lesions and to cancerous oral mucosa," said Dr Sudb. "There was COX-2 expressio...First potentially clinically useful independent marker for lung cancer identified
...the first clinically useful independent prognostic marker for early stage resected patients with non-small c...te our findings, but this is the first independent marker for NSCLC with potential clinical utility. Our studies have opened up an avenue for further investig...Ovarian cancer detected in blood samples
... test, employing a standard ovarian cancer protein marker (CA125) currently used to monitor disease, added little improvement in detection rates, Shih reported. "A test based on digital SNP holds promise for improved detection in a wide range of cancers, as well as ovarian cancer, which is currently detect...Blood proteins tied to inflammation
...am found that high levels of C-reactive protein, a marker of inflammation, and low levels of albumin, a sign of malnutrition, had strong ties to heart disease in these patients, who are many times more likely to develop heart problems than the general population. "Both inflammation and malnutrition play an...Stomach-dwelling H. pylori bacterium reveals its age
...aphical populations and therefore can be used as a marker for these populations. Specific variations in the vacA gene, for instance, are found only in East Asian countries such as China, Korea, and Japan. Even when people from these countries migrate to North America, the strains of H. pylori that their chi...High selenium consumption may protect ex-smokers from bladder cancer
...o detect trace quantities of selenium. "A selenium marker should preferably reflect long-term selenium intak...ium intake instead of serum selenium, a short-term marker of selenium intake. "Available evidence suggests that selenium levels in toenails reflect intake int......er radiotherapy First potentially useful clinical marker for lung cancer identified First results from phase I trial of a novel anti-angiogenic agent Novel target for causing cancer cell death identified First clinical trial for genetically engineered mistletoe analogue EU clinical trials jeopardised b...Study provides direct evidence of the role of telomeres in prostate cancer development
...tening has been proposed as an early and prevalent marker of prostate cancer process, according to a study presented today at the American Association for Cancer Research's first annual Frontiers in Cancer Prevention Research meeting. Findings of the study provide the first direct evidence that human prost...Chemical society convenes regional meeting in Albuquerque, October 12-15
... focus on the technology used to analyze a protein marker for breast cancer. (Vince Martin, Department of Chemistry, University of Wyoming, Laramie, 307-766-2680, vince@uwyo.edu ) Two chemists from New Mexico will receive special recognition during the meeting for their professional achievements in divers...New guide helps researchers mine genome data
...tains only one STS, stSG47693. By clicking on the marker name, users can obtain more details about the STS ...allows users to see the genomic context of the STS marker in all maps to which it has been mapped. The NHGRI authors emphasize that the new user's guide is a...First-ever cancer prevention research meeting
...on: Telomere shortening as an early and prevalent marker of the cancer process in several malignancies. Genetic testing to help drive people to be screened for colorectal cancer. "Despite the substantial progress in cancer prevention, there are still many obstacles to overcome," explains Dr. Hong. "Futur...Southern 'stroke belt' study initiates nationwide study
...d sugar, kidney function, and C-reactive protein,a marker of inflammation that has been associated with increased risk forheart disease. In later analyses, the researchers will look at blood-clotting factors, DNA markers, vitamin levels, and other markers of inflammation. "Our role as the central labor...University of Pittsburgh Cancer Institute discovers proteins linked to colon cancer
...ssue. "Identifying a specific and sensitive tumor marker that would allow reliable early detection of colon cancer and predict the potential for the cancer to spread or recur would be of great benefit to patients," said Dr. Getzenberg. "Early diagnosis of recurrent colon cancer is critical to effective tre...JCI table of contents: October 1, 2002
... antibody and vasculitis: much more than a disease marker Vivette D'Agati Columbia Univ Col P and S 630 W 168th St New York, NY 10032 USA Phone 1: 212-305-7460 E-mail: vdd1@columbia.edu See PDF of the article at: https://www.the-jci.org/press/15918.pdf and the commentary at: https://www.the-jci.org/p...Biologists new experiment may vindicate Darwin
...d flies from the darker one. The bristles act as a marker that Fry can track over generations. The leftover flies in each habitat are then allowed to reproduce before being sent back to the lobby to make a habitat choice again. Initially, Fry does not expect much correlation between bristle number and the i...Tiny, magnetic spheres may help overcome gene therapy hurdle
...ed microspheres, with the researchers tracking the marker proteins through a technique called fluorescence m...xperiments revealed 10 times the expression of the marker protein in the target organ the lung than in other organs, indicating the microspheres both could ...Loblolly pine open for genetic engineering, research shows
...," said Gould. The transformation was done with a marker gene merely to prove that such genetic transfer could be done and that plants carrying the gene could be regenerated. Gould's method for transforming plants - using a plant's meristem region for inoculation with Agrobacterium - was patented by the ...Bone marrow cells may contribute to growth of new blood vessels in newborns
...ors injected the cells, which contained a chemical marker to identify them, into newborn mice within three days of birth. Some of the animals also were injected with VEGF. A few mice were injected at four weeks of age to test whether EPCs contributed to blood-vessel growth in older animals. The mice were ex...New predictor of heart disease risk found
...ns have discovered that this protein is not just a marker for heart disease, but that it actually damages the blood vessel wall by blocking a critical "protector" protein and by promoting plaque formation. The finding, published in the September 17 issue of the journal Circulation (available on the Web at ...Scientists identify gene variant associated with arrhythmia in African Americans
...d with other risk factors, may one day be a useful marker for the prediction of arrhythmia. At present, there is no test generally available to identify this gene variant. An estimated 4.6 million African Americans carry the gene variant. Peter Spooner, Ph.D., leader of the Arrhythmia, Ischemia, and Sudden...