A thermodynamic history traces temperature's effect on Universe, Earth and humans
...Age. ... For the past 200 years, I could use as a marker the ever-lower temperatures achieved in laboratories as, one by one, all known species of gas were liquefied. As the millennium came to an end, the low-temperature scale reached billionths of a degree above absolute zero." Ever wonder what's so spec...Gene trigger for pancreas formation identified
... so the investigators were able to follow the blue marker in these cells. They found that, with p48 absent, the cells that normally express p48 and go on to form pancreas became intestinal cells instead. And they became all types of cells in the intestines, including intestinal stem cells. It is the first...New predictive marker found for prostate and colon cancer
...in" is correct spelling.) "Anytime you find a true marker for cancer, it's surprising," says Theodora S. Ross, M.D., Ph.D., an oncologist in the U-M's Comprehensive Cancer Center and an assistant professor of internal medicine in the U-M Medical School. "But HIP1 also is unusual, because it seems to be such...Low-carbohydrate, high-protein diets increase risk of kidney stones and may raise bone loss risk
...iseases. Researchers report that acid excretion a marker for the acid load in the blood increased as much as 90 percent while subjects were on diets that severely restricted carbohydrates. Levels of urinary citrate, which inhibits kidney stones, fell by almost 25 percent in the group during the six-week s...Rose breeding blooms from backyard to genetics lab
..., and one reason to do that is to hopefully find a marker to indicate whether a plant has a certain gene or not." The researcher plans to look at other traits that determine whether a rose is easy to grow in a landscape such as disease resistance, fragrances and the everblooming trait. But that's not the o...Other highlights in the July 17 issue of JNCI
...e suggested that expression of these proteins is a marker of epithelial carcinogenesis. Kai Stoeber, M.D., of the University of Cambridge, Gareth Williams, Ph.D., of University College London, and colleagues tested whether measuring Mcm5 levels in urine could detect the presence of bladder cancer. They tes...New signaling pathway found, may be linked to movement disorders
...pears blue when exposed to certain chemicals. This marker molecule revealed that FGF14 was primarily found in three regions of the mouse nervous system: the cerebellum and basal ganglia in the brain and the motor tracts of the spinal cord. All three areas are involved in regulating movement. The basal gangl...Applied Biosystems launches Assays-on-Demand SNP genotyping and gene expression products
...g products provide a high-resolution, gene-centric marker map that should be useful for researchers performing association studies for disease states, potential drug candidates and drug response. Single nucleotide polymorphisms (SNPs), which occur up to every 100-300 bases in both coding and noncoding regi...Low hemoglobin means high risk for mobility problems in elderly women
...n, Chaves says. Among older adults, it is often a marker of chronic diseases and can cause symptoms including fatigue, chest pain, shortness of breath and dizziness. Currently, physicians recommend their patients take some combination of iron, folate and vitamin B12 supplements for anemia associated with ...UT Southwestern researchers discover better tests to detect congenital syphilis in newborns
...M antibodies seems to be the best single surrogate marker for substantiating infection of the infant." The blotting test, similar to an AIDS diagnostic tool, is a molecular technique for detecting IgM antibodies in the serum of infected infants. "I believe that this work, spanning more than a decade, will s...Applied Biosystems introduces new system for protein and metabolite analysis
... platforms to identify drug targets and diagnostic marker candidates and to discover novel therapeutics. Its Celera Discovery System online platform, to be marketed exclusively through the Knowledge Business of Applied Biosystems, is an integrated source of information based on the human genome and other b...New technology creates 'super soap'
...them against a plastic surface pre-coated with the marker bacteria. The bacteria transferred from the plate to the hands were recovered and quantified by standard microbiological methods. In three clinical studies, the bacteria attachment to the hands washed with the MAT-containing soap was reduced by a sta...Unique population of muscle stem cells found in mice
...ittsburgh. In addition, we were able to use a gene marker to prove that these cells were incorporated into the musculature of mdx mice. The cells continued to proliferate, make dystrophin and improve muscle regeneration. MDS cells were tagged with the LacZ reporter gene and traced, Dr. Huard explained, addi...Cosmic impacts implicated in both the rise and fall of dinosaurs
..., which is common in space objects, creates a time marker for comet or asteroid impacts." said Kent. "Correl... is reversed. This reverse zone can now serve as a marker to help identify the boundary location in the geological record. "Our research adds to the specul...Gene thats key to cloning success also hints at serious hurdles to reproductive cloning
...tive human cloning." The Penn team chose Oct4 as a marker because its expression is tightly regulated throughout the mammalian life cycle. Oct4, which encodes a protein critical to normal embryonic development, is expressed only in the portion of the embryo that eventually gives rise to fetal tissues; in t...Astrocytes play starring role in neural stem cell development
...d adult neural stem cells with a green fluorescent marker so they could follow the development of those cells. When they grew the tagged stem cells in cell culture with both astrocytes and other neurons, the stem cells readily developed into mature neurons. However, when the scientists grew the tagged stem ...Hopkins researchers test new molecular marker for prostate cancer
...t AMACR could not only serve as an excellent early marker for prostate cancer but also could identify new di... the last two years as a potential prostate cancer marker by researchers at the Corixa Corporation and then at the University of Massachusetts Medical School ...New gene-silencing enzyme discovered: Implications seen for treating aggressive cancers
...genes. The enzyme functions by placing a molecular marker on a gene that causes the gene to be silenced. When this molecular marker is lost, certain genes may be improperly reactivated, which can result in cancer. Discovery of the e...Researchers link gene with kidney stones, bone loss in patients who absorb too much calcium
...uded from the study. The study provides a definite marker for kidney-stone risk, but it also could lead to early-stage identification and treatment for bone loss and osteoporosis, Gitomer said. As part of the study, patients bone mineral density in the lower spine was measured, and the presence of one or mo......mising early results show that RhoC can serve as a marker for breast tumors that are most likely to spread, ... cancer had little RhoC. This is a very promising marker for small but invasive breast cancers that may metastasize, which right now are hard to identify, sa...