Newly identified master gene key in baby's first breath
...ildren's Hospital Medical Center have identified a master gene that controls the first breath a newborn infa...entified as having roles in lung development, this master gene, called Foxa2, controls key factors that allow the lungs of a fetus to develop fully and eventu...Indiana University, EPA to study airborne PCBs
...er and precipitation samples are collected at five master sites and 10 satellite sites in the United States ...ng data from air and precipitation samples at four master stations (near Lakes Superior, Michigan, Erie and Ontario) and two satellite stations (Chicago and C...New anti-inflammatory strategy for cancer therapy identified by UCSD researchers
...uired for the activation of NF-kB, which acts as a master switch to turn on inflammation in response to bacterial or viral infections. In turn, NF-kB sets off a chain of reactions that lead to cancer. Mice used in the new study were given colon or breast tumor cells which metastasized to the lung. ...Popular Science announces Third Annual 'Brilliant 10'
...y simple principles that make it work." And like a master watchmaker, he is looking for a set of universal laws that describe the rhythms of plant and animal life. The principles that he and his colleagues are discovering appear to reveal deep biological truths about everything from the way cells consume nu...Single isolated mouse skin cell can generate into variety of epidermal tissues
...rchers didn't know if hair and skin arose from one master cell -- a "multipotent" stem cell that can morph into a number of tissue types -- or from two populations of "unipotent" stem cells that are destined to be a single tissue. "There has been increasing evidence that there are cells within this compart...Advances in tumor angiogenesis Dendritic cells co-opted to the dark side
...nencia. It is well established that VEGF-A is the master switch for tumor angiogenesis, with a dose-dependent effect: in this case, dendritic cells were converted into endothelial-like cells only in the presence of high VEGF-A levels. "The levels of VEGF-A generated in our animal model of ovarian cancer re...Genetically-engineered 'marathon mouse' keeps on running
...ring the gene for a protein called PPAR-delta -- a master regulator of numerous genes -- to enhance that protein's activity. According to Evans, they had not expected the profound and far-reaching physiological effects of this single genetic alteration. "In previous work, we had shown that in various tissu......es of all these different clocks is the job of the master circadian oscillator, or master clock, which in humans and other mammals is the suprachiasmatic nuclei, a small center in the brain'...Embryonic stem cell therapy shows steady benefits in rebuilding infarcted heart
...m cells, Mayo Clinic researchers transformed these master cell types into fully functional cardiac cells and transplanted them into damaged regions of the myocardium, where the cells integrated into the infarct and showed rapid and robust improvements, which were stable over an extended period post-therapy....UCSD researchers are first to demonstrate molecular link between inflammation and cancer
...led nuclear factor kappa B (NF-kB), that acts as a master switch to turn on inflammation in response to bacterial or viral infections. In epithelial cells, NF-kB promotes the development of cancer not through inflammation, but through inhibition of a cell-killing process called apoptosis. In myeloid cells...Casanova or caveman: Scientists isolate nerve cells that choreograph male fly's courtship behavior
...s had previously discovered that fruitless was the master gene that controlled sexual behavior in male flies. "We found that the fruitless gene was responsible for building the neuronal circuitry for male courtship," Baker said. "This circuit, which is built into the fly's brain and ventral nerve cord, is c......e pair collaborate with Rick Naill, a musician and master teacher at the Colburn School of Music, and Anna Pattison and Peggy Tsutsui of the USC Dental School, who are training the next generation of dental hygienists. "If we understand an individual's body mechanics and control mechanisms, we can help the......ormone that relays the message to the thyroid, the master of metabolism. Once activated, the thyroid gland then spreads word to the body's cells to increase energy production. Research results are published in the online early edition of the Proceedings of the National Academy of Sciences for the week of ...... a complex chain of molecular events, triggered by master control proteins. These control proteins act as recruiting officers, rallying other proteins to set up the inflammatory defense. One of the most important molecular sergeants is a protein called nuclear factor-kappa B (NF-kB), which can order the pro......earch colleagues discovered that Rac is one of the master regulators of cell motilitythe molecules driving t...to become active in the first place. What were the master switches that control the activity of Rac and the fundamental cell processes it controls? All that...K-State business researchers to help with major study on food supply veterinary medicine
...and services management and a course for K-State's master of business administration program, has research interests in improving and management of the performance of front-line, customer-contact employees, consumer-to-consumer interactions via the internet, consumer relationship benefits and corporate spon...Newborn lambs' central heating system could aid fat busting in humans
...mmals and not others. During development so called master fat determination genes or PPARs govern whether an immature cell commits to becoming a fat cell, explains Dr Fouzia Sadiq of Imperial's Animal Science Research section. "A further signal, PGC- 1 alpha is then needed to convert immature fat cells into...Bird's song may be linked to speech disorders
...w medications for speech disorders, she said. As a master gene regulates eye development, "FoxP2 may be a master gene involved in setting up structures required for facial control and vocalization," White said. Wh...Research to create lung-cancer blood tests receives $3.4M in Pennsylvania tobacco settlement funds
...he National Cancer Institute. The tobacco master settlement law, Act 77 of 2001, says that each year settlement dollars will go toward addressing research priorities that are established and reviewed annually by a statewide Health Research Advisory Committee, which is chaired by the Secretary of He...UT Southwestern researchers identify gene as essential for vascular smooth muscle development
... during disease." Dr. Olson recently discovered a master regulator of smooth muscle development, a protein called myocardin. This regulator turns on smooth muscle genes by interacting with serum response factor (SRF), a widely expressed protein that binds DNA. In the Nature study, Dr. Olson and his colleag...