Gene's role in malaria drug resistance proved
...ected with, then health officials would be able to match whatever drugs work best against the most prevalent local or regional variant," he explains. Dr. Fidock conducted earlier phases of this research as a member of NIAID's Laboratory of Malaria and Vector Research. The head of that lab, Thomas E. Wel...Ancient defense mechanism may still be protecting us
...This means the only RNAs remaining are copies that match some foreign DNA that sneaked into the lock box of the small nucleus since it last produced the larger one. These RNAs then head back out of the dying large nucleus toward the new large nucleus of the next generation. There, they look for the matchin...Evolution upset: Oxygen-making microbes came last, not first
...s Blank. Reasonable as all this sounds, it doesn't match the genetic evolutionary tree, she says. In Blank's version of the story, the sulfur-loving bacteria came on the scene at about 2.4 billion years ago, and the Cyanobacteria came along at least 100 million years later, she says. Because banded iron ...Tailor-made cancer drugs: Wave of the future?
...nd a nucleic acid triggering sequence, designed to match and interlock with a unique or uniquely overexpressed strand of RNA in cancerous cells. The RNA binding drug components will be fashioned out of Peptide Nucleic Acid (PNA), which is identical to DNA, but replaces the sugar backbone with a "peptide" o...Global warming has uneven effect on coastal animals
...ers put temperature loggers, modified to thermally match living mussels, in mussel beds at eight sites spanning 14 degrees of latitude ranging from northern Washington to Point Conception, Calif. and measured temperatures over the course of a year. They found that Lompoc Landing, Calif., one of the more so...Genetic clash doubles schizophrenia risk
...h-negative pregnant women whose Rh factors did not match their fetuses'. Now widely used, the drug prevents women's immune systems from destroying their babies' red blood cells. Still, a large number of Rh-incompatible children living today were born before prophylaxis was available. The UCLA team decided ...UCSD bioengineers use computer model to predict evolution of bacteria
...y experiment of E-coli growing on glycerol did not match the rate of growth predicted by the computer model. On a hunch, he guessed that this particular strain of E-coli had not been exposed to glycerol before, and that if he gave the bacteria time to evolve, it might reach an optimum growth rate. To tes...Once big bad wolf, now man's best friend: Science studies trace dogs' origins
... sequences from ancient Latin American dogs didn't match any from modern dogs. Thus, the researchers concluded, European colonists probably did not use Native American dogs to create the breeds that we know today. "These dogs were left behind by modern breeding programs," Vil said. Both research teams stud...Jewels that may help explain behavioral disorders found among 'junk' DNA
...on, the CRH smnRNA appears to form a complimentary match with a sequence in an untranslated region associated with a receptor, called the NMDA-glutamate receptor, which is widely implicated in schizophrenia and other degenerative neurological disorders. The members of McInnes' research team are Esther Rich...Science picksLeads, feeds and story seeds (December 2002)
...sently available on the website will be updated to match the revised maps, including the ground-shaking levels for 150,000 sites, the seismicity catalogs and fault parameters used to make the updated maps, customizable hazard mapping and being able to create hazardous earthquake scenarios for a given locat...Prize to Weizmann Institute professor for landmark work in stem cell transplantation
...nsplantations could only succeed if a full genetic match existed between the donor and recipient. Patients ...ee of six immunological markers be matched. Such a match is always present between parents and children, and there is a 75% chance of finding it among siblin...K-State researchers use Colbert Hills process to study ecosystem of former landfill site...
...lorida, it may not tell them anything. You have to match indicators to the situation." It is that transportable process that Western Michigan and others are interested in. "They don't want to know the exact conditions at Colbert Hills because their ecosystems are different, Thien said. "They want to know ...$24-million grant funds local researchers to create encyclopedia of the innate immune system
... are produced in almost infinite variety and which match a particular disease organism like a key in a lock, cells of the innate immune system react generically to a wide range of substances, including molecules found in the cell walls of many bacteria. The grant investigators aim to identify and study the...Powerful technologies probe innate immunity
... are produced in almost infinite variety and which match a particular disease organism like a key in a lock, cells of the innate immune system react generically to a wide range of substances, including molecules found in the cell walls of many kinds of bacteria. An encyclopedic account of these complex an...Two Max Planck researchers recieve the Louis-Jeantet Prize for Medicine 2003
...another person. This mirror neuron system seems to match action observation and execution and may, therefore, constitute an important brain basis for social cognition. With the Louis-Jeantet Prize for medicine, Riitta Hari wants to study the effects of observed pain on brain activation of the observer. By ...Brain imaging study sheds light on inner workings of human intelligence
...a curve ball: showing them a new item that did not match the oldest item, but did match one nearby in the on-going sequence. Participants found these 'lure' items to be especially distract...Science champion William T. Golden makes historic $5.25 million gift to AAAS
...957--a time when U.S. researchers were striving to match Soviet achievements in space. In 1996, Mr. Golden received the National Academy of Sciences Public Welfare Medal--the Academy's highest honor. NAS President Bruce Albert attributed Mr. Golden's contributions to science and public welfare to "his insa...Washington-area chemist wins national award for free-radical research
...g reactions that otherwise wouldn't take place. "A match flame is full of small free radicals -- without them, the flame would go away," Jacox pointed out. "And the fluoride-containing molecules used in etching microcircuits -- a lot of the chemistry of those reactions involve small free radicals I've stud......with a matching sequence. If an siRNA is chosen to match the RNA copied from a particular gene, it will stop production of the protein the gene codes for (see Graphic). Huntington's is caused by mutations in the huntingtin gene. The resulting defective protein forms large clumps that gradually kill off par...New technique gives scientists clearest picture yet of all the genes of an animal
...56 percent the predicted genes did not completely match the actual genes isolated in their study. "This demonstrates that even in C. elegans whose genome is better understood than humans' the genome map needs a great deal of correcting and refining," Vidal says. "We're still a long way from having a pe...