Researchers identify gene that controls formation of heart chambers
...leting Bop in mouse embryos consistently disrupted maturation of heart-muscle cells and stymied formation of the right ventricle. The findings should be applicable to humans, Srivastava said, because genetic parallels can be found in heart development among all animal species, including the fruit fly. Thats th...Neural stem cells can develop into functional neurons
...whether astrocytes played a role in triggering the maturation of adult neural stem cells, the scientists cultured the cells with both neonatal and adult astrocytes. The studies showed that both types of astrocytes produced factors that supported stem cell maturation. According to Stevens, the observation that a...Scientists discuss microbial pathogenesis in era of bioterrorism, drug resistance
...teria to surfaces, formation of a microcolony, and maturation into a biofilm. P. aeruginosa causes a variety of persistent and chronic infectious diseases, including those in the lungs of cystic fibrosis patients and on the skin of burn patients. Dr. Kaplans laboratory has been studying the twitching movement...Study finds new reason for smokers to keep this unhealthy habit away from infants/children
...inical problems found in premature infants, before maturation of the surfactant synthesis system has occurred. These infants with severe lung dysfunction are now treated with synthetic surfactant. Surfactant production is also perturbed in smokers and perhaps in those exposed to second hand or side-stream ciga...Vitamin C transporter gene discovery in mice
...onths of human gestation. A child born before this maturation is at high risk for these complications in the immediate postnatal period. What Im suggesting is that we need to take a look at whether vitamin C in human fetuses before birth, transported from the maternal circulation, is a normal physiological fac...Astrocytes play starring role in neural stem cell development
...ay actually play a starring role in triggering the maturation and proliferation of adult neural stem cells. The ... encouraged both stem cell proliferation and their maturation into neurons. "We found that stem cells grown on glia divided about twice as fast as they did when g...What a difference a decade makes
...tical question: Are there differences due to brain maturation or are any of the differences simply the result of slower and less accurate performance by children? To answer this key question, they divided the participants into two categories: The matched category contained performance data that was similar for ...Warming temperatures may freeze North American timber industry
...es in northern regions areeventually offset by the maturation of softwood forests, but notenough to make up for the interim loss." In the long run - after 100 years or so - an increase in timberproduction in northern and southern regions will likely increase theannual growth of marketable timber by raising glob...Promising new therapies for deadly form of leukemia
... normally switches on at specific times during the maturation of blood cells. In AML, however, the gene for FLT3 is mutated, so that it produces a receptor that is constantly or constitutively active. This activity disrupts the blood cells' development and causes uncontrolled proliferation. The most common fo...Brain-derived neurotrophic factor (BDNF): From maternal deprivation to manic depressive illness
...suggested that adverse life events during neuronal maturation can be critical for brain development thus producing persistent changes in its function and increasing the vulnerability to psychiatric disorders. Such vulnerability is related to the coping ability under challenging situation, such as stress, which ...UC Riverside's Alexander Raikhel awarded $4.3 million grant from NIH to study mosquitoes
...olecular mechanisms regulating egg development and maturation in mosquitoes. Funded by the National Institute of Allergy and Infectious Diseases (NIAID), the research has implications on preventing mosquitoes' transmission of deadly diseases, including West Nile virus and Dengue Fever. "NIH rarely grants award...Big-bottomed sheep have a rare genetic mutation that builds muscle, not fat
...oma and neuroblastoma, and also is involved in the maturation of fat cells and the adrenal gland, said Jirtle. DLK-1 is imprinted, lending further credence to the assumption that callipyge is also imprinted. "Imprinted genes are like mushrooms, because they are present in groups," said Jirtle. "Moreover, they d...Scientists reveal a new way viruses cause cells to self-destruct
...tein-cleaving enzyme, or protease, to complete the maturation of newly synthesized virus particles. Similar to t...leave several viral proteins to complete the viral maturation process. There were no indications that the protease could be activated in the cell's cytoplasm. Whe...JCI Table of Contents, November 18, 2002
...******** Arginine deficiency affects early B cell maturation and lymphoid organdevelopment in transgenic mice CONTACT: Wouter H. Lamers University of Amsterdam Department of Anatomy and Embryology Academic Medical Center Meibergdreef 15 Amsterdam, 1105 AZ THE NETHERLANDS Phone 1: 31-20-566-5405 Fax 1: 31-20-...JCI Table of Contents, December 2, 2002
...eteangiopoietin-1 (Ang1). Multiple roles in vessel maturation have beendesignated to Ang1 and they include sprou...ial cells and mural cells facilitatethe growth and maturation of new blood vessels. In diseases such as diabeticretinopathy, mural cells are absent from the vesse...Gene responsible for anemia (type CDA-1) discovered
...PO) may yield a better understanding of blood cell maturation and anemia and eventually lead to an effective remedy for CDA-1. Prof Lancet's research is supported by Wolfson Family Charitable Trust, Crown Human Genome Center, Henri and Francoise Glasberg Foundation, Alfried Krupp von Bohlen und Halbach Found...... entire life cycle of a cell -- its proliferation, maturation and death. Fox is short for Forkhead Box, a name referring to a mutation in the gene in the fruit fly that causes a duplication in the head structure. One key finding came last year: Costa's research group was studying the FoxM1B gene in mice; in p...... first to find a receptor that participates in egg maturation and ovulation. The current work is actually the se...mature. In human beings, the trigger for this egg maturation process is unknown. In worms, it is a signaling protein released by sperm. Miller and Greenstein i......to the oocyte cell membrane, and it signals oocyte maturation only when sperm are present. This discovery lends ...s, has identified several components of the oocyte maturation signal transduction pathway in C. elegans. It is known that MSP from the sperm activates a mitogen-a......ause for "storage," during which they go through a maturation process that prepares them for penetrating the egg. A sperm cell that has completed this maturation process detaches itself from the wall and leaves the storage site. If ovulation had taken place in t...