Dangerous Chemical Combination Presents Possible Scenario For Gulf War Illnesses
... to and damage the brain and nervoussystem. Such a mechanism could explain the wide array of symptoms reportedby some Gulf War veterans, including memory loss, headache, fatigue, muscleand joint pain, weakness, shortness of breath and tremors, the researcherssaid. "The decision to use these chemicals was made......r common health care problems." Insights into the mechanism of amphetamine drugs derived from studying the"kno...information should providenew understanding of the mechanism of amphetamine drugs and new strategiesfor treating amphetamine addiction." Besides dopamine's dire...Enzyme's "Magic" May Hold Key to Anticancer and Antimicrobial Drugs
...olecular picture that basically proves the mechanism [by which the enzyme works]," said Dr. Wang. "This in turn has implications in the design of anticancer drugs." The studies reveal that yeast topoisomerase II is heart-shaped, with a gaping hole in its center. Althou...New Cancer Switch Discovered By Duke Medical Center Pharmacologists
...gast. The Abi proteins may be a previously unknown mechanism for producing cancer, said Pendergast, not by direct damage to a cancer gene, but by damage to a "safety key" that is its partner....Key to Triplet Repeat Brain Diseases Open Door For New Way To Understand, Treat Genetic Diseases"
...n a disease. This is an observationthat provides a mechanism for a group of diseases." If drugs could block the protein interaction the researchers described,then the discovery may offer treatment options, according to Roses. The investigators became interested in the action of repeated gene sequencesin bra...Researchers Pinpoint Site For Petit Mal Seizures In Brain
...will allow the research team to pinpoint the exact mechanism by which GABAb receptors can cause absence seizures. Armed with the new information about the mechanism, Hosford plans to look for compounds that inhibit only those GABAb receptors affected in petit mal seizures, which the scientists hope will allow ...New Discovery About Genes Has Implications For Genetic Therapy
...hers that they were seeing a holdover to a similar mechanism that must have taken place in the earliest evoluti...ally," Lambowitz said. "We were interested in the mechanism by which they do this." He said that the mechanism involves integration of the intron's RNA into th...Mutate Or Die: New Polymerase Gives Desperate Yeast An Option
...licating past the damaged site is the leastfavored mechanism of dealing with DNA damage, but from the cell's perspective, it's better to replicate damaged DNA andsurvive than to not replicate and die," says Christopher Lawrence, professor of biophysics. Working with Lawrence on theproject, funded by the Nation...... to this set-up, Raff saysin The Sciences. "Such a mechanism could ensure that any cell that ends upin the wron... naturallyself-destruct. When the self-destruction mechanism is disrupted, though,cancerous tumors made up of rapidly reproducing cells can result....Researchers Find Possible New Route to Making Cancer Cells Vulnerable
...g,"Heitman said. "Our findings shed light on a new mechanism that canbe exploited to overcome drug resistance i...umor cells,"Heitman said. "Simply jamming the pump mechanism may not be enough."...Nitric Oxide May Hold Key To First Treatment For Deadly Form Of Malaria, Duke Scientists Report
... Cell,describes an entirely new cellular signaling mechanism -- the attachmentof nitric oxide (NO) to a key portion of a protein called a thiol -- thatcan directly activate genes. The work was funded by the National Heart,Lung and Blood Institute, a division of the National Institutes of Health. The ...Low-Protein Diet May Reverse Kidney Disease
...ilding blocks of protein. "We still don't know the mechanism for this surprising result," says Walser. "Evidently, some unidentified component of a regular diet was perpetuating the loss of urinary protein. What's clear from our findings is that the common opinion that kidney disease patients shouldn't be give...Nitric Oxide Found To Control Cells By Turning On Genes; Suggests New Role In Health And Disease
... Cell,describes an entirely new cellular signaling mechanism -- the attachmentof nitric oxide (NO) to a key portion of a protein called a thiol -- thatcan directly activate genes. The work was funded by the National Heart,Lung and Blood Institute, a division of the National Institutes of Health. The ...Changing Continental Runoff Patterns Could Change Ocean Circulation
...It appears that salinity in the Tethys Sea was the mechanism that switched deep water formation from the cold poles to the warmer subtropics," says Bice. "In a future, warmer Earth, human alterations to fresh water runoff and surface salinity might have the same effect."...Scientists Identify Retrovirus-Like Components In Corn Genome
..., there's a possibility that maize has developed a mechanism to defeat them in some way." His group now is init... the retroviruses from causing disease. "If such a mechanism exists, scientists may be able to apply it to help animals and humans fight retroviruses, which caus...Animal Studies Indicate Aging Brain Responsive To Estrogen
...stein said their research also suggests a possible mechanism to explainrecent findings that women on hormone re...llular studies in Einstein's lab thatnow suggest a mechanism for this improvement in memory. In the study, the team used aging female rats that had their ovarie...Bacterial Protein Structure Hints At Mechanism Of A Class Of Premature Aging Diseases
...nt to know how it causesthe disease." If the mechanism of a genetic malfunction can be mapped out, said Bastia,drug therapies will be easier to design as would gene therapies. The newresearch is the first step in that direction. The Duke researchers have shown that the RTP, rather than simply actin...Disease Resistance Mechanism Identified in Plants
A molecular mechanism for plant disease resistance has been identified f...he plant. Researchers suspect that the resistance mechanism observed in tomatoes also occurs in many other plants. Their results appear in the December 20 issu...Mechanism For Disease Resistance Identified In Plants
A molecular mechanism for plant disease resistance has been identified f...he plant. Researchers suspect that the resistance mechanism observed in tomatoes also occurs in many other plants. Their results appear in the December 20 issu...Researchers Find How Disease-resistant Plants Recognize Bacteria
... various defense mechanisms. "By understanding the mechanism of disease resistance in plants, we hope to improv...es at Purdue struggled to understand the molecular mechanism of disease resistance. One puzzle was why the protein that provides resistance to infection is found...