Researcher Discovers Plant Genes For Phosphate Uptake
...iency. Perhaps, he thought, he could find out what mechanism makes plants better at phosphorus uptake, then track down the genes that turn on that mechanism. He predicts that once they understand it, researchers might enhance a plant's natural ability to compete for the few phosphate molecules found free in so...First Selenium-Based Orally-Active Antihypertensive May Lead To New Family Of Therapeutic Agents
...d. "We don't believe these compounds have aunique mechanism of action. What is exciting is that their biochemicalactivity depends on selenium." Researchers From Mercer UniversityCollaborate on Studies To develop a better understanding of the compounds' potential value,May's research group collaborated wi...Max-Planck Researchers Unravel The Structure Of The Methane Forming Enzyme
...o the general design and the detailed enzymatic mechanism of such a complex biochemical reaction. Moreover, this structure can serve as reference point, to interprete more reliable biochemical and spectroscopic observations and to characterize the structures of other enzyme states in the future....Harbor Branch Oceanographic Institution Receives $1.1 Million Grant From National Cancer Institute
...he compound to be a potent anti-tumor agent with a mechanism of action similar to that of the clinical anti-cancer agent Taxol. Both Taxol and discodermolide interact with microtubules, structures which compose the framework or "cytoskeleton" of normal and cancer cells. These compounds bind to, and "freeze",......ovel human gene which is directly involved in a mechanism of regulation of autoimmune response. The gene is ...as such is not a common disease, the underlying mechanism of this disease may be common to other autoimmune conditions, such as diabetes and rheumatoid art...Scientists Identify A Novel Mitotic Regulatory Mechanism
...erable implications in the understanding of the mechanism of cell division. The eukaryotic cell cyc...t regulation of mitotic progression via a novel mechanism involving binding of a specialized protein (a so called peptidyl-prolyl cis/trans isomerase) t...Green Tea Ingredient Can Kill Cancer Cells
...ds investigators to a greater understanding of the mechanism involved in the process. If they can decipher the molecular mechanism by which green tea imparts protective effects, the knowledge may provide opportunities to interfere ...Human Breast Milk Contains Obesity Hormone
...in is important to the neonate, we know there is a mechanism for it to get from the intestine to the bloodstream." No one knows yet if leptin is present in cow's milk, or if the pasteurization process damages the hormone, Houseknecht adds. Researchers don't know whether leptin offers any advantages or ...Pitt Researchers Construct Novel Delivery System For Gene Therapy Of Liver Disorders
...ucted thefirst prototype of this "car," a delivery mechanism for genes called areconstituted chylomicron remnant (RCR) that has resulted in the extendedproduction of therapeutic proteins in an animal model, according to a reportpublished in the Dec. 23 Proceedings of the National Academy of Sciences. ...MIT Biologists Identify Aging Mechanism
CAMBRIDGE, Mass.--MIT biologists have identified a mechanism of aging in yeastcells that suggests researchers m...aging process in certain human cells. The mechanism of aging, it turns out, is elegant in its simplicity.During a yeast cell's life, whenever a particul...Researchers Discover New Genetic Risk For Alzheimer's Disease
...gene and Alzheimer's disease. But no one knew of a mechanism by which APOE mightlead to the disorder. In additi...er's disease," Goateexplained. "And we believe the mechanism involves another protein calledamyloid." In animal models of the disease, other researchers...Peutz-Jeghers Disease Gene Identified: Enzyme Loss Causes Polyps And Cancer
... control and signal transduction. The molecular mechanism by which STK11 controls cellular differentiation in the gastrointestinal tract and in other organs is currently unknown. The search for physiological STK11 substrates will yield further insights into the complicated intracellular network ......fit theregional agriculture community, but that no mechanism existed for transferringtechnologies and ideas out...nzymes and food and animalfeed supplements. A new mechanism known as a "shuttle vector," which transfersdesirable gene sequences to the genome of a host micro-o......The structure yields important clues regarding the mechanism by which helicaseenzymes unravel double-stranded n...ral data we have unveiled also suggests a possible mechanism of nucleicacid unwinding for this and related helicases. " "The solution of the HCV helicase struc......, M. F. WALTER and J. M. MASON A protein-counting mechanism for telomere length regulation in yeast D. SHORE, S. MARCAND and D. WOTTON Chromatin and telomeres in ageing in yeast and mammals B. KENNEDY, N. AUSTRIACO, D. LOMBARD, K. MILLS, T. SMEAL, R. MARCINIAK, S. MA, D. SINCLAIR and L. GUARENTE The limit...Technique Gives Researchers New Look At Genetic Activity In Living Cells
...tive, mechanical system for the separation. Such a mechanism had been thought to exist only in eukaryotic organismssuch as plants and animals.......cripps Research Institute have not onlyuncovered a mechanism to help explain angiogenesis activity, but have de...w blood vessel growth toward tumors. The mechanism that controls the delicate balance of biological processesthat tips the scales in favor of blood ves...Transposable Elements May Have Had A Major Role In The Evolution Of Higher Organisms
...ry cell. The second major gene-silencing mechanism in higher organisms is calledmethylation. McDonald points out that the vast majority of methylated genesequences in humans and other vertebrates are contained in transposableelements. Thus, McDonald argues, it is likely that methylation and other rel...Low B Vitamin Levels Common In Many People Linked To Increased Heart Disease, Stroke Risk
...icient diet have developed disease, he says. The mechanism for the blood vessel damage is unclear, although other research has suggested that vitamin B-6 deficiency, in addition to raising homocysteine levels, may make the blood more prone to forming the blood clots that can obstruct blood vessels or alter l......ut toxins Epel's own research illustrates a coping mechanism that may be useful for anadult but is essential to...cs. Epel has identified the MDR transporter as one mechanism that an adult fatinnkeeper worm uses to survive in some of the most polluted mud flats along thePaci...