Tag: "melanoma" at biology news

Fruits offer powerful protection from skin cancer

...ls) inhibitor of both UVB-induced non-melanoma and melanoma in a transgenic animal model," said Janine Einspahr, Ph.D., of the Arizona Cancer Center in Tucson, and lead author of the study. "We are confident that further research will garner results that support these findings in human models. Phase I and ...

Dose of PTEN protein found to determine progression of prostate cancer

...ant tumors. In humans, these were shown to include melanoma and cancers of the breast, prostate, and brain. Although the loss of just one Pten gene is enough to affect cell signaling, the loss has only been associated with slow-growing, mild lesions in the mouse prostate, comparable to early stages of the hum...

Zadaxin in triple therapy shows 61% response for hepatitis C non-responders

...tis B clinical trial in Japan, a phase 2 malignant melanoma clinical trial in Europe, two phase 2 liver cancer pilot studies in the U.S., and a phase 3 hepatitis C pilot study in Mexico. Other drug development candidates include SCV-07, a potentially orally available therapeutic to treat viral and infectious...

World's largest scientific society holds regional meeting in Long Beach, Calif.

...arrett, gbarrett@unr.edu ) 1:35 p.m. Targeting melanoma via metal-based oxidative stress Melanins are bl...velopments that target melanin pigments within the melanoma cancers. (Patrick J. Farmer, University of California, Irvine, Department of Chemistry, School of Ph...

New way of examining lymph tissue detects hidden melanoma

... of a very small tissue sample can identify hidden melanoma metastases in lymph nodes. The presence of melanoma in the lymph nodes is the single most important factor in determining a patient's prognosis and is a...

Retinoblastoma survivors face increased risk of a second cancer

...inactivated before a cell starts to develop into a melanoma or sarcoma. In some of these genes, including the retinoblastoma gene, both the maternal and paternal copies of the gene have to be inactivated by two independent events before cancer starts. If someone already has an inactivated copy of the gene b...

ITA to AMA: Taxing tanning sends wrong health message to teens

...n, ovary, uterus, kidney, and prostate, as well as melanoma and non-Hodgkin's lymphoma. "In addition, the acc...ions. For example, the editorial grossly misstates melanoma deaths (7,600 in 2003 according to the American Cancer Society, not 45,000, as the article alleged.)...

Cancer biologists and a cardiologist take a new look at aggressive tumors

...lly our observations indicated that the aggressive melanoma tumor cells behaved in a similar manner as do endo...et another example of the plasticity of aggressive melanoma tumor cells in that they can mimic other cell types, such as endothelial cells, and our study provid...

New funding mechanism for melanoma research announced

...r dedicated to pursuing the prevention and cure of melanoma by presenting the Fellow with the research funds t...to promote the pursuit of innovative and promising melanoma research. The AACR is pleased to co-sponsor this exciting new program with the William S. Graham Fou...

Sex matters in health promotion and disease prevention

... report, Greenberger pointed out, the incidence of melanoma is higher in women, but the mortality rate is higher among men. Many researchers attribute the difference in incidence to behavioral factors such as occupational and recreational activities, clothing styles, and willingness to use sunscreen. Differ...

Scientists identify mechanism for tumor death by radiation

...d for endothelial cellsto undergo apoptosis. When melanoma and fibro-sarcoma cells wereimplanted into mice, the tumors that developed in the acidsphingomyelinase deficient (asmase -/-) mice showed reduced endothelialapoptosis, had a tumor growth rate almost double that of the normal acidsphingomyelinase ( as...

Technique brings immune-based therapies closer to reality

...as experimental "cancer vaccines" in patients with melanoma and multiple myeloma and as virus fighters after b...wth and exposing the beads to antigens from either melanoma or cytomegalovirus. "Using the aAPCs, we were able to make a tremendous amount of CTLs while main...

Rutgers researcher discovers melanoma causing gene

...titute, in the United States the incidence rate of melanoma has more than doubled in the past 20 years. Chen h...rio School of Pharmacy. "I did not set out to do a melanoma study," said Chen. "All my life I have been interested in cell transformation and differentiation. ...

DNA-based vaccine triples survival for dogs with melanoma

...K April 8, 2003 The options for treating advanced melanoma are limited - regardless of whether the patient is...an last fall at MSKCC for people with high risk of melanoma recurrence. "Most medicines that we use to treat animals are the same as those given to humans," exp...

Brain gliomas progress as function of crucial gene is lost

...is lost. They have found that other tumors such as melanoma become increasingly deadly when the gene is no longer active, and have described its role in breast and prostate cancer as well. The AP-2( transcription factor controls the expression of many genes, including c-Kit, which regulates cellular prolifer...

Antibody therapy can increase the effectiveness of cancer vaccine, early studys

...treated with cancer vaccines for either metastatic melanoma or metastatic ovarian cancer. The result, in every...nd two had metastatic ovarian cancer. In all three melanoma patients who had been treated with one form of vaccine, tumors showed extensive signs of cell death ...

New immune-boosting cancer treatment shows promise

...er vaccines. Three of the patients with metastatic melanoma and two with ovarian cancer had received a vaccine... and his colleagues at DFCI. Four other metastatic melanoma patients had received different vaccines based on immune-stimulating antigens specific to melanomas....

Study may help explain sunlight's role in melanoma development, have screening implications

...icularly lifetime sunburns, and the development of melanoma - the most lethal form of skin cancer. Now, fo...by ultraviolet light exposure, thereby speeding up melanoma development. New findings published in the Feb. 4 issue of Proceedings of the National Academy o...

Researcher explores tumors' survival strategy

...is increased in breast cancer, prostate cancer and melanoma and decreased in ovarian cancer. "The bottom line is that the environment that supports the growth of cancer cells and their development into tumors is regulated by a multitude of factors. One of these factors is SPARC or a class of proteins like it,...

Vaccine technique shows potential against common form of lung cancer

...er parts of the body. The researchers created the melanoma vaccine by removing a portion of a patients tumor ...tent, long-lasting immune response targeted at the melanoma tumor cells and produced only minor side effects. In the lung cancer study, researchers develop...

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