New Gene May Play Important Role In Regulating HDL, The 'Good' Cholesterol
...protein produced by the new gene becomes the third member of a group ofenzymes called triacylglyerol lipases, known to influence HDL metabolism. It isproduced by endothelial cells, a subset of cells that includes those that linevessels and arteries, and is called endothelial lipase (EL). Researchers at Rhon...Researchers Find Vaginal Bacteria Imbalance Might Boost AIDS Risk
...and gynecology; Juan L. Granados, a UNC-CH faculty member on theWake Medical Center staff; and David A. Savitz, professor and chair ofepidemiology. "These findings may explain why black women have been disproportionatelyaffected by HIV, something we have not understood before," Royce said. "Thiswork...Jefferson Scientists Find Further Proof Of Damage To The FHIT Gene In Breast Cancers
...y and immunology at Jefferson Medical College anda member of Jefferson's Kimmel Cancer Center, showed reduced levels of Fhit, theprotein for which FHIT encodes, both in women with sporadic breast cancer andthose with hereditary breast cancer who carry a BRCA2 mutation, a genepredisposing them to develop the...National Science Board Honors Maxine Frank Singer With Vannevar Bush Award
...ties in thescientific community," said Vera Rubin, member of the National Science Board andstaff member at Carnegie's Department of Terrestrial Magnetism. In 1989, Singer introduced "Project First...Genes Found That Label Cell Proteins For Disposal
...t leads toimbalance of proteins." Xiong, a member of the UNC Lineberger Comprehensive Cancer Center,points to the known tumor suppressor p53 as an example. Normally, p53 is presentwithin cells in relatively minute amounts. "If it's degraded too much, theprotein never accumulates and you get tumor de...A 'Missing Link' Fossil Adds 'Foliage' To The Early Human Ancestor Family Tree
...s. "The hominid fossils may allow us to add a new member to the humanevolutionary family tree," said Weiss, "and the evidence regarding the use ofstone tools in food processing indicates an early reliance on meat in hominiddiet. This adaptation would have allowed them to venture into new habitats andultim...Sharks Get Porthole Of Opportunity
...w York-based WildlifeConservation Society (WCS), a member of the Ocean Wildlife Campaign. The rules, part of a sweeping management plan for Atlantic and GulfCoast fisheries signed into law on April 26, call for major cuts in bothcommercial and recreational shark-fishing quotas, including a moratoriu...The Origins Of Hereditary Breast Cancer -- Studies With Knock-Out Mice Reveal Underlying Mechanisms
... of the DeutscheForschungsgemeinschaft (DFG), is a member of a group of scientists led byChu-Xia Deng and Lothar Hennighausen at the National Institutes of Health (NIH).By using an animal model this group has now elucidated the mechanism underlyinghereditary breast cancer. The results of their studies with ......ator of the Cardiovascular Research Institute, and member ofthe UCSF Cancer Center Program in Cell Cycle Disregulation at the University ofCalifornia, San Francisco. Co-authors for this study are postdoctoral fellowXiang-He Lei, PhD; graduate fellow Xun Shen and research associate Xiao-qin Xu.Postdoctoral f...Rockefeller University Scientists Receive Prestigious Awards For Cancer Research
..., thenation's first medical research institute. A member of the National Academy ofSciences, he has received many honors, including the 1998 Horwitz Prize andawards from Memorial Sloan-Kettering Cancer Center, Bristol-Myers Squibb, EliLilly, the University of Texas M.D. Anderson Cancer Center, and the Stra...Urban Restorer Sees Trash Trees, Beetles As Signs Of Hope
...s, Mo., in August. The Penn State faculty member in the College of Arts and Architecture will present a paper, "Patterns, Processes and Paradigms - Toward EcologicalVital Brownfields," at that symposium. The Nine Mile Run restoration program is supported in part by grantsfrom the Heinz End...NICHD Researchers Discover Gene For Major Brain Structure
... hippocampus." The gene, termed Lhx5, is a member of the family of genes known as theLIM Homeobox genes, noted Dr. Westphal. Homeobox genes have changed littleduring the course of evolution and seem to fulfill similar functions, fromroundworm to man. Essentially, these genes pave the way for devel...Walker named a Fellow of the British Royal Society
...92. He was named a MacArthur Fellow in 1988 and a member ofthe American Academy of Arts and Sciences in 199...tates in 1973. From 1974 to 1978 he was a faculty member atHarvard University, where he was associated with Harvard Medical School, thePeabody Museum, and th...UCSF Research Team Looking For Volunteers For Nationwide Study On Family Traits And Alcoholism
...orrecovering alcoholics and who also have a family member who will take part inthe study. All participants must be 18 years of age or older and free fromaddiction to other drugs, except nicotine. Study volunteers must take part in a telephone interview about use of alcoholand other drugs, complete a penci...UCSF-Led Team Offers New Insight Into Neurological Basis Of Dyslexia
... Francis A. Sooy Professor of Otolaryngology and a member ofthe Keck Center for Integrative Neuroscience at ...assistant adjunct professor ofotolaryngology and a member of the Keck Center for Integrative Neuroscience atUCSF, and the lead scientist of the study, "was de...Protein Misfolding, Not Mutant Gene, Key To Lethal Sleep Disorder
...normal gene in any tissue. A search found nofamily member with a similar disease. The researchers then used extracts fromthe patient's brain and from the brain of a different patient with confirmed FFIto transmit the disorder to transgenic mice with a mouse/human prion proteingene. The neuropathology in the...'Cousin' Of Snake Venom Toxin Found In Mice
...e toxin called alpha-bungarotoxin. This venom is a member of alarge family of proteins called Ly-6. With that in mind, Heintz and Miwa namedtheir gene "lynx," for Ly -6 n euroto x in. "At that point we realized the potential significance of lynx1," Miwa said."Bungarotoxin was known to bind to acetylcholi......nsity for suchmaps," writes Kruglyak, an associate member of the Hutchinson Center's divisionsof Human Biology and Public Health Sciences. Kruglyak predicts researchers instead will need to locate at least half amillion such "mile markers"along the DNA highway if geneticists are to stay ontrack when chasing...Nematode makes scientific history
...h Esnard, a nematologist at Cornell University and member of the AmericanPhytopathological Society and Society of Nematologists. "The sequence providesplant nematologists with a supermarket of nematode genes to shop from." The completion of sequencing the C. elegans genome is also significant from thepoint ......onservation Division atCREW and an adjunct faculty member at UC. Plair is now a researcher at CREW. This spring, they tried out their methods at the La Selva preserve in Costa Ricarun by the Organization of Tropical Studies. The techniques are designed to befast, simple, and not harmful to the living plan...