Tag: "membrane" at biology news

UH lab identifies first gene mutations in blood vessel disease

...in the legs, hypertension and stroke. Rupture of a membrane at the back of the retina causes bleeding that lea...hen drug compounds are not carried across the cell membrane into the cell. ABC transporters do not typically carry calcium, but miscoding in the gene may cause ...

Virus linked to Kaposi's sarcoma sabotages immune system with a new and unusual strategy

...o be detected experimentally - travels to the cell membrane to cause MHC-1 to become vulnerable to the cell's endocytic machinery, or -- in a more radical proposal -- the proteins may trigger a signaling pathway from their internal location that induces the cell's surface proteins to carry out the sequesterin...

Lasers to the aid of embryos

...precision drilling the 'shell' of a human egg -- a membrane an average 18 millionths of a metre thick (six times smaller than the smallest object visible to the human eye). Delegates at the European Society of Human Reproduction and Embryology conference in Bologna, Italy, heard today (Tuesday 27 June) from H...

Life from the skies

...ting, ending up with a lipid bilayer just like the membrane around all living cells (see Diagram, below, and Inside Science, this issue). "On re-entry, the aerosol with its monolayer of surfactants comes down to another part of the ocean and picks up a second layer that would be different," says Tuck. "This...

U-M scientist finds molecule plants use to control early cell development

... traditional view is that changes outside the cell membrane caused by ligand binding lead to changes inside the cell, which start the signaling process. For CLV1, it appears that information also flows from inside the cell to the outside. Unless it receives these chemical signals from inside the cell, the r...

Even the Immune System works with Pincers

...cked the anchor peptide which is used for the membrane attachment on the immunological active cells. As all antibodies of the immunoglobulin IgG and of the allergy triggering IgE consist of similar amino acid sequences and also have similar Fc receptors, the scientists from Martinsried/German...

Fuel cell research center to develop and test new technologies

... fuel cell technology for use with electrochemical membrane devices that clean fuel, gases and other substance... for compact, small-scale or micro proton exchange membrane fuel cells; (5) development of an advanced room-temperature, sodium-based battery for high power and...

UB biophysicist receives $2.7 million Jacob Javits award to continue distinguished research in neuroscience

...s to move through the receptor protein, across the membrane and into the muscle cell. This ion movement, in turn, triggers a whole cascade of events that eventually leads to muscle contraction. "In the brain, neurons communicating with other neurons communicating with still other neurons is the physical ba...

Scientists map first structure in important family of proteins

...o be mapped, rhodopsin is now one of only about 10 membrane proteins that have been mapped to such detail. That's because membrane proteins are not easily crystallized. Most proteins that have been analyzed so far are soluble, and ...

'Gatekeeper' protein is key to cellular life; links bacteria, chloroplasts and mitochondria

...serves as a gatekeeper of sorts, allowing into the membrane other proteins essential for the bacteria to live.... "independent" proteins were able to pass into the membrane on their own. The new discovery, reported in this week's issue of the journal Nature, may suggest a ...

Molecular switch that inhibits fat cell development found

...," Ross says. When Wnt protein binds to a cell membrane receptor, it sets off a chain of biochemical signals, according to Ross. Signals are passed from one messenger molecule to another until they reach the cell nucleus where they either turn on or turn off genes that regulate development. Ross demo...

UCSF researchers identify regulator of critical brain messenger, hinting at therapy

...ught it was a protein that functions on the plasma membrane to transport inorganic phosphate into a neuron....

Measuring alcohol levels in breath, blood and now the brain

...ll characterize the biophysics of alcohol/neuronal membrane interactions that will likely result in alcohol intoxication, tolerance, and dependence. In short, a better understanding of the molecular interactions that are associated with these behavioral states should lead to the development of treatment opti...

Small molecules used to block proteins in HIV

...p a molecule that can both pass through the cell's membrane and block the proteins isn't easy to accomplish," she says. "The molecules we developed are 50 times smaller than the dimeric enzyme they must block, so it's like David taking on Goliath. But I think we've learned a lot over the past ten years about ...

Magnetic fluids offer hope for treatment of retinal detachment

... age, tears in the retina can occur. A hole in the membrane allows fluid to leak;when the retina is not suppor...he retina back against the underlying choroid, the membrane between the retina and the sclera. Scleral buckles -- narrow, supportive bands that can be placed ar...

Gene for Mucolipidosis IV discovered

...umulation of fats and sugars in their lysosomes -- membrane bound intracellular sacs that function in food digestion. Most importantly, the collaborative team has found several specific mutations that cause the disease in different groups of patients. ML4 is recessive, meaning that the disease may appear...

Cellular membrane changes associated with acclimation to cold

...ing deep hibernation. "This study shows a physical membrane change through which cells may acclimate to extrem...ese slits correlated with patches of internal cell membrane devoid of protein, something that was not seen seen on images of non-hypothermic tissues. The intern...

Gene alterations for cystic fibrosis may also account for chronic sinus problems in some

...ic fibrosis (CF), which is characterized by mucous membrane abnormalities in the lungs, appear also to contribute to chronic sinus problems in some people, according to a report in this week's Journal of the American Medical Association. About 14 percent of the general U.S. population suffers from chronic si...

Golgi lipids regulate protein trafficking

...s lysophospholipids, which are thought to regulate membrane fusion during protein secretion. Choukroun et al...umulation of phospholipid metabolites in the Golgi membrane causes this organelle to vesiculate during cell division....

UCSF team reveals how the most selective of all cell gatekeepers works -- a 'three-faced' channel vital to most human organs

...apeutic drugs affect movement of molecules through membrane channels -- research that can help develop treatme...euromuscular control are based on highly selective membrane channels, so to understand how these channels function shows us how the principal 'transistors' of t...

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