Tag: "membranes" at biology news

Researchers reveal calcium transport protein function that regulates heartbeat frequency, strength

...they move together. "Transporters move ions across membranes by grabbing hold of them and transferring the energy of one type of ion to another type, just one or a few at a time, backwards and forward, together or in exchange for one another," Dr. Hilgemann said. "This is a much bigger biophysical problem to g...

Examining cardiac performance of tunas at the cellular level

...n blot analysis, proteins were transferred to PVDF membranes and probed with a polyclonal antibody specific to cardiac SERCA2. Blots were developed using a secondary antibody kit. SERCA2 content was assessed. Results The researchers found that: The measurements of oxalate-supported Ca2+ uptake in SR en...

Molecular level discovery could play role in development of new antibiotics

... a double-edged sword. They form holes in the cell membranes and also bind to intermediate targets of a disease-causing bacterium. Hitting on two targets simultaneously reduces the risk of resistance occurring, van der Donk said. "We are interested in antibiotics that are used commercially and that are not che...

Study finds huge variability in vitamin E absorption

...that prevents oxidation of polyunsaturated fats in membranes and lipoproteins, including the LDL and HDL forms of cholesterol. Although the scientific community is still divided in its conclusions, some studies suggest vitamin E has an important role to play in a healthy cardiovascular, neurologic and immune s...

Peregrine falcons may face new environmental threat

...g been considered too big a molecule to cross cell membranes and be taken up by wildlife or humans. "This is th...ggs," de Wit says. "Thus, deca seems to cross cell membranes without too much trouble." The new findings add to growing concern that the deca molecule might not ...

'Smart bomb' delivery destroys tumors in mice

... the tender tissues, or by cooks making sauce, the membranes separating the compartments are ruptured and rapid allicin production follows. The scientists realized that if doses of allicin could be repeatedly generated in this way at the site of the tumor, the highest concentration of the toxic molecules would...

Quark Biotech generates a cholesterol-free mouse

... indispensable structural block of cells and their membranes and plays major roles in signal transduction. The paper entitled "Generation of Viable Cholesterol-Free Mice," appears in Science , December 19, 2003 (Vol. 302, Page 2087). "We were surprised by the fact that a mouse lacking cholesterol can survive ...

Ultraviolet irradiation in ventilation systems could reduce office sickness

...-related symptoms such as irritation of the mucous membranes of theeyes, throat, and nose, as well as respiratory symptoms. Dick Menzies fromthe Montreal Chest Institute, McGill University, Canada, and colleaguesassessed whether ultraviolet germicidal irradiation (UVGI) of drip pans andcooling coils within off...

Protein-hungry cells 'go fishing,' report Purdue biologists

...y lies in the organization of the receptors in the membranes themselves. "Receptors tend to lie together in clusters," he said. "Biologists have long found a concentration of one type of receptor mixed in with a few other types, much as elephants and giraffes congregate on the plains, while other species are f...

Effects of maternal myasthenia gravis on pregnancy and birth examined

...l group (8.6 percent). Preterm rupture of amniotic membranes occurred three times more often ? or 5.5 percent ? compared to 1.7 percent of the general population. MG is a chronic autoimmune disease that causes muscle weakness. In people with MG, cells of the immune system make protein antibodies that block ne...

Naked mole-rats bare pain relief clues

...type of pain associated with Substance P in mucous membranes throughout the animals' bodies -- they have become insensitive to the pain. Another possibility involves Substance P and blood vessel dilation in the skin -- to cool the body surface. In cold-blooded naked mole-rats, however, dilation would cause th...

Multiphoton microscope observes cell membrane action

ITHACA, N.Y. -- Cell membranes -- the sacs encompassing the body's living matter ...ioning the surfaces. Their report on observing the membranes -- a laboratory-grown mixture of phospholipids and cholesterol -- being reshaped into two separate, ...

Purdue biologists' spotlight solves mysteries of photosynthesis, metabolism

...etween the cell and its surroundings. "Plant cell membranes are like the two ends of a battery," said Janet Smith, professor of biological sciences and the team member responsible for much of the structure analysis. "They are positive on the inside and negative on the outside, and they are charged up when sol...

Could a specific protein contribute to erectile dysfunction for the diabetic and obese?

... on 10% SDS-PAGE and transferred to nitrocellulose membranes followed by incubation with anti-PKC and Rho-kinas...hoA antibodies for 3 h at 20 C. After washing, the membranes were incubated with secondary antibodies for 1 h at 20 C. For chemiluminescent detection, the membr...

Tiny 'test tubes' may aid pharmaceutical R&D

...easuring micrometers in diameter, the fluid-filled membranes are currently used in cosmetics and for drug delivery. The NIST team developed an improved method for using liposomes as tiny test tubes for mixing chemicals with volumes measured in trillionths of liters. Their experimental setup allows simultaneous...

Fruit fly pheromone receptor first ever discovered linked to specific sexual behavior

...rs, which are the protein switches nestled in cell membranes that trigger responses to pheromones, said Duke Medical Center geneticist Hubert Amrein, Ph.D., senior author of the study. Now, he and co-author Steven Bray, also of Duke, report that male Drosophila fruit flies lacking one type of taste receptor ha...

Scientists: Cloak of human proteins gets HIV into cells

...n act like an exosome, tiny pockets made from cell membranes that are used to send molecules between cells. Gould, an expert in the basic biology of the cell, Hildreth, an expert on HIV's biology, and graduate student Amy Booth also reviewed decades of scientific reports about the viral envelope or "particle" ...

Laboratory 'theme park' re-creates RNA world for study

....J., believes that primordial soup was filled with membranes (garbage bags) that contained random chemicals not nearly as complex as RNA or DNA. These chemicals began catalyzing reactions in each other, some of which eventually caused the cell-like garbage bags to divide and thus evolve. Proponents of this vie...

Endostatin also effective on head and neck cancers

...y also produce an enzyme that actually digests the membranes of the cells they're trying to take over....

Lipids get the spotlight in new NIGMS 'Glue Grant'

... an energy reserve for the cell. They make up cell membranes and are involved in communication within and between cells. "Lipids are the most important biomolecules because they are the ultimate controllers and regulators of our bodily processes," said Edward Dennis, Ph.D., a chemistry and biochemistry profes...

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