Tag: "merlin" at biology news
Researchers identify important function of NF2 tumor suppressor
...work of filaments that supports the cell. "Since merlin
is a tumor suppressor whose loss of function leads...ell-to-cell communications. The researchers found merlin
in the adherens junctions of normal cells and discovered that adding normal merlin
protein to cultur...
The magic behind merlin
A new study reveals an essential role for the merlin
protein in maintaining the junctions between cells...ce) in the May 1 issue of Genes & Development. The merlin
protein is encoded by the NF2 gene. Mutations in NF2 cause neurofibromatosis type 2, a hereditary ca...
Merlin tells when to grow and when to stop
... tumor suppressor, merlin, functions. Mutations in merlin
cause Neurofibromatosis type 2 (NF2), a common inh...ates the pathway by which cells that are mutant in merlin
become tumorigenic. Cell density is one of several growth-limiting parameters. Normal cells prolifer...