Tag: "metabolic" at biology news
UT Southwestern receives $1.78 million grant for obesity research as part of NIH Roadmap initiative
...alth to study the causes of obesity and associated metabolic
diseases. The $1.78 million grant, part of the NIH...will provide bigger steps toward understanding the metabolic
processes that lead to obesity and some of the metabolic
syndromes commonly associated with obesity,...
Winning combination to build bone density in children
...Interactive effects of vigorous activity (≥6 metabolic
equivalents) and calcium intake were found at the total body in boys (b = 2.90 x 10-3) and in girls (b = 6.58 x 10-3) and at the proximal femur (b = 9.87 x 10-5) and femoral neck (b = 2.29 x 10-5; where b is the regression coefficient from final equa...
16 APS exercise research highlights, from reduced flu mortality to proteomics & obesity
...pport the restoration of skeletal muscle power and metabolic
capacity in COPD patients towards sedentary contro... profiling provides unique insight into underlying metabolic
crisis in chronically untrained muscle and clues as to how exercise reverses these effects....
March of Dimes statement on newborn screening report
...ur inclusion criteria, and include all of the nine metabolic
tests plus hearing screening contained in our previous policy. We will revise our periodic evaluation of states' performance on newborn screening to include at least these 30. We will urge states to provide test results for an additional 25 "r...
Microbes eat their way to better concrete
...e microbes seal concrete surface cracks with their metabolic
byproducts. That's already been done, so Bang and ...ineering to create microbes that produce even more metabolic
byproducts. The researchers will put the microbes through a wide range of concrete performance tests...
Environmental decontamination, greenhouse gases, and the genome of a methane-loving bacterium
...at this methane specialist can turn into a sort of metabolic
generalist-with a capacity to use sugars, hydrogen, and sulfur-and appears able to survive reduced oxygen levels. The M. capsulatus genome provides a platform for investigating the details of methanotroph biology and its potential as a biotech w...
Scientists explore genome of methane-breathing microbe
..., found an unexpected flexibility in M. capsulatus metabolic
pathways, hinting that the bacterium is capable of...ion of methane. They also found genes that suggest metabolic
flexibility, including the microbe's likely ability to grow on sugars, to oxidize sulfur, and to liv...
Information system to help scientists analyze mechanisms of social behavior
...n three broad areas: systems biology, cellular and metabolic
engineering, and genome technology. "We are pleased to provide the institutional support for BeeSpace, which will be a flagship project for the institute," said Harris Lewin, IGB director and professor of animal sciences. "We are putting significant...
Joslin researchers clarify mechanisms for beta-cell formation
...or contributor to type 2 diabetes, obesity and the metabolic
syndrome, which affect nearly one-quarter of the American population. For years, the body compensates for insulin resistance in order to delay the onset of clinical type 2 diabetes: The pancreas secretes more insulin and, in fact, more insulin-p...
New fruitfly model of diabetes has future implications for pancreatic cell transplantation
...tus of an animal can adjust an animal's growth and metabolic
state," he says. "Now we have a model for that." Coaxing stem cells to become pancreatic islet cells for transplantation is potentially a permanent treatment for diabetes. As a developmental biologist, Rulifson is now concentrating on how the pr...
Research on carbohydrate metabolism receives historical recognition
...rk ultimately advanced scientific understanding of metabolic
regulation. Both Carl and Gerty Cori were born in Prague (then part of the Austro-Hungarian Empire) in 1896. They met in Vienna while attending medical school and married in 1920. They immigrated to the United States in 1922 and then moved to St...
Purdue study finds antioxidant protects metal-eating plants
...etals like nickel in minute quantities for certain metabolic
processes, but at high levels metals can damage membranes, DNA and other cell components. Most plants try to keep the levels of metals in their cells at a minimum, but plants called metal hyperaccumulators have the unique ability to build up unusuall...
Protein involved in childhood disorder linked to cancer
...s incur chronic DNA damage from exposure to normal metabolic
byproducts as well as external chemicals and radiation. In order to mitigate this DNA damage, cells must have a mechanism for both detecting damage and for stopping their machinery until the damage is fixed. This feedback mechanism relies on cycle "c...
Highlights of American Chemical Society national meeting in Philadelphia, Aug. 22-26
...ew of biochemistry by quantitatively measuring the metabolic
pool size of all of the biochemicals in a sample. This is often referred to as metabolomics. With this approach, "we have discovered potential biomarkers that could be diagnostic for ALS and are working to validate our findings," says Chris Beecher...
Integrative biology of exercise APS Intersociety meeting October 6-9, 2004 in Austin
...dwin. AMP-activated protein kinase: regulation of metabolic
and transcription processes in contracting skeletal muscle. Chair Neil Ruderman. Comparative biomechanics and muscle function in terrestrial vertebrates: in vivo studies. Chair Donald F. Hoyt and James Hicks. In addition to the formal sessions, ...
Marathoning mice could have Olympian effects on obesity
...scle makeup and help resist obesity and associated metabolic
disorders. To test the concept, Evans and his team treated normal mice with an experimental drug called GW501516 that activates PPAR-delta. These mice also expressed genes for slow-twitch muscles and gained less weight when given a high-fat diet. Th...
Engineering endurance: The future of the Olympics?
...t fuels many essential cell processes. A number of metabolic
pathways supply muscle tissue with the ATP needed ...lucose or fatty acids) are used; it also generates metabolic
by-products, like lactic acid, during strenuous exercise. (Runners know the "lactic acid burn" assoc...
Genetically-engineered 'marathon mouse' keeps on running
...to their large numbers of mitochondria the cell's metabolic
power plants, with which they convert fat to energ...d that treatment with the drug produced muscle and metabolic
benefits similar to what they saw in the transgenic mice. The researchers also found that the genet...
Sweet success in targeting sugar molecules to cells in living animals
... significant advance in the promising new field of metabolic
engineering because it provides a new tool with wh...urface of cells. Sugars are synthesized by complex metabolic
pathways, and it was thought that integrating a marker into a specific sugar molecule would inevitab...
When is a mouse like a test tube?
... marked cells as a function of the robustness of a metabolic
pathway, the sialic acid biosynthetic pathway," Bertozzi said. "This offers an alternative way to visualize cells that are undergoing a change in metabolism, such as happens with cancer cells and inflamed cells that over-produce sialic acid. The tech...
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