Tag: "metabolic" at biology news

Possible mechanism for link between diabetes and Alzheimer's disease discovered

...or contributor to type 2 diabetes, obesity and the metabolic syndrome, which affect nearly one-quarter of the A...oduced by the pancreas, leading to a wide range of metabolic abnormalities. In patients with diabetes, this includes elevated blood sugar levels which, if uncon...

Data shows FUZEON does not increase lipodystrophy in pre-treated HIV patients

... as "fat redistribution" and can be accompanied by metabolic changes (rises in levels of fats and sugar in the blood). Latest FUZEON data This new analysis included DEXA (dual x-ray absorptiometry) body composition scans in a sub-group of patients in the TORO studies, which showed that those in the FUZEON a...

Making of mouse marks move toward 'mitochondrial medicine'

...rategies and therapies for patients with incurable metabolic diseases affected by mitochondrial function."...

Researchers adapt RNA interference to study gene function on a large scale

...nd many that produced proteins involved in general metabolic processes such as the ribosomes that are components of the protein synthesis machinery," said Perrimon. "But we also found genes that are more specific to cell survival." According to Perrimon, only 20 percent of the genes that were identified had co...

Examining cardiac performance of tunas at the cellular level

...ll swift, powerful swimmers that benefit from high metabolic rates - and that in order to support these rates, ...step in the evolution of the tuna's high heart and metabolic rates is the result of an increase a key protein SERCA2. Their findings also suggest that high leve...

Other highlights in the February 4 issue of JNCI

...d an elevated insulin response may contribute to a metabolic environment conducive to tumor growth. Simin Liu, M.D., Sc.D., of Harvard Medical School and Brigham and Women's Hospital, and colleagues looked at information gathered from the Women's Health Study. They looked at the association between dietary gly...

JCI table of contents, February 2, 2004

...entify enzyme deficiency underlying sweet-smelling metabolic disease Maple syrup urine disease (MSUD) is an in... now the choice for newborn screening for up to 40 metabolic disorders within both the USA and Europe. Through the use of mutagenesis in mice and screening of th...

Scientists report first sequencing of environmental genome

...s, they were able to reconstruct nearly the entire metabolic cycle. Already they have determined how the microb...hen be used to explore the nature of the community metabolic network, to find conditions for cultivating previously uncultivated organisms, to monitor community ...

Microbial biofilm yields community genomes, metabolic clues

...w findings enhancescientists' understanding of the metabolic activity of ironoxidizing microbes that greatly accelerates acid production. Nine other scientists from Berkeley and the Department ofEnergy's Joint Genome Institute in Walnut Creek, Calif., coauthored the report. The study was funded by the Nationa...

New species of desert shrew found in southern Arizona

...body heat quickly. To compensate, they have a high metabolic rate. Unless they eat often, they will starve to death. Desert shrews are vicious predators. To satisfy their rapacious appetites, they devour juicy insects, such as crickets, and the occasional small mouse, which is about five to 10 times their own ...

Integrated animal model answers questions about environment

...n breathing. Getting enough oxygen is critical for metabolic processes, which supply energy to the body. Given the known levels of pesticides in the air before the birds died, Porter calculated daily pesticide inhalation. It was toxic over a short period of time, he says. The Wisconsin scientist forwarded thi...

One-size-fits-all approach to nutrition recommendations may soon be outdated

...s multiple factors such as age, gender, lifestyle, metabolic and genetic make-up, activity level and predisposition to disease. "While the customization trend may sound ideal for those seeking the "perfect" diet, there are key issues that need to be resolved before the trend is embraced by all,' cautions Hool...

Rodents bred for alcohol preference live longer than rats bred for alcohol avoidance

...del in mind," he said. "First, rats have a higher metabolic capacity than humans. This means that even if rats drink alcohol as their only source of fluid, they are able to metabolize alcohol so efficiently that they have measurable amounts of alcohol in their blood only a few times during the day. Therefor...

Bacteriophage genomics approach to antimicrobial drug discovery published in Nature Biotechnology

...or of the publication. "This binding shuts off key metabolic processes in the bacteria, diverting those organisms from their own growth and reproduction to the production of new phage progeny. We believe these phage-identified bacterial "weak spots" will provide useful screening targets for discovering the sor...

New device can help defend against novel biological agents

...gain." They ran similar tests with two other known metabolic poisons, antimycin A and 2,4-dinitrophenol, and a type of cell that produces connective tissue called a fibroblast and got similar results. Last year, the Vanderbilt researchers upgraded a Cytosensor at the Edgewood Chemical Biological Center at the ...

Researchers seek to clone 'mad cow disease' resistant cattle strain

...pathogenic forms. Proteins, the building blocks of metabolic processes, are long chains of amino acids that fold in upon themselves in predictable patterns and shapes that result from the bio-electrical relationships that exist between individual molecules, according to Eyestone. Proteins normally "fold" in on...

Wright State biologist studies birds to learn how our stomachs convey thoughts of hunger

...tanding of these clocks in the gut with respect to metabolic conditions, and also to shed light on why we get hungry when we do and why we often eat more than we should." The Wright State faculty member has presented several lectures on this topic in the past year in Japan and the U.S. and has been pursuing ...

Quark Biotech generates a cholesterol-free mouse

...tand the mechanism of action of existing drugs for metabolic diseases and cancer, among others." The study supp...el strategies of drug discovery, for instance, for metabolic diseases." The resulting mild effects of the disruption of desmosterol reductase in this model cont...

Scientists discover how anthrax creates its deadly spores

...us) are theonly bacteria that can shut down normal metabolic functions and convertrapidly into dormant, protective spores when environmental conditionsmake it impossible for them to otherwise survive. Scientists have been studying anthrax spores since 1876, when they werefirst described by the pioneering Germa...

Researchers uncover pathway that could lead to plant generation of human-like protein

...see 95 percent," Joshi said. "So we are working on metabolic engineering methods to enhance the levels of enzymes involved in these reactions in the plant to get maximum yield. The researchers will continue their work on the new pathways, exploiting systems that exist in plants, rather than adding a gene to a ...

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