Colorado U. to fly hardware, experiments on space shuttle, space station
...g the genetic control mechanism involved in lignin metabolism has broad applications in the timber and pharmaceutical industries, he said. BioServe is part of a consortium collaborating on the plant experiments on the space station that also involves the NASA-Ames Research Center, the U.S. Department of Agricu...Scientists discover genetic defect responsible for microcephaly
...ch Branch at NHGRI. "It makes a tie between energy metabolism and brain development." Five other genes have been...and then look for other connections between energy metabolism and brain development," Dr. Biesecker adds. A diagnosis of microcephaly means a baby's head circumfe...Researchers discover genes that control regulatory functions in malaria mosquitoes
...the vertebrate blood meal for its own development, metabolism and reproduction. The importance of that connection could be crucial to understanding how the parasites are passed to humans and create disease. "Since most peptide types exist as single-copy genes, each is a target for genetic interference," s...Parasite, mosquito genomes complete malaria picture
...e response cells. Other genes involved in parasite metabolism have no counterparts in humans. Inhibitors of those genes' products could be developed into anti-malarial drugs. Information from the Anopheles genome is giving researchers new insights into mosquito physiology and behavior, including the insect's ab...Misfolding the key to protein's ability to kill brain cells
... may somehow alter the cell's metabolism or affect some signaling pathway within the cell, which may lead to an accumulation of PrP in the cytosol, causing the cell to die. "We've been able to show that PrPsc can initially form...Is being big clam on the block a factor in species success?
...ase, the culprit is likely the fact that bivalves' metabolism is higher. They are more active. That may be what is controlling size, rather than environment," says Krause. "The fact that this size difference seems to have not changed in the last 400 million years despite major ecological changes is really inter...UCSD bioengineers develop first computer model that predicts disease variant based on genetic defect
...g a computer model that is based on the well-known metabolism in the human red blood cell. "The model is like ...n 30 years of chemistry and biology research about metabolism in the red blood cell, which is one of the human body's simplest and most well-understood cell types...Study finds relationship between geriatric frailty, biology
...y and increased inflammation, altered carbohydrate metabolism and increased blood-clotting activity. While further research is needed, this is an important step toward predicting, preventing and treating frailty in the aging population. "This is exciting research for the geriatric population," explained Jeremy ...JCI Table of Contents, November 18, 2002
...indings in thecontext of our understanding of bone metabolism and comments on potentialtherapeutic benefits and ...iver is required for normal carbohydrate and lipid metabolism in vivo. CONTACT: Wataru Ogawa Division of Diabetes and Digestive and Kidney Diseases Kobe Universit...Clock cues: Cellular sensing, metabolism research wins Amersham Biosciences and Science Prize
...as diseases such as osteoporosis. His work on bone metabolism may also suggest targets for the treatment of autoimmune conditions like rheumatoid arthritis. JAPAN/Ferrying Cargo in the Brain: The brain contains a busy transportation system that shuttles neurotransmitters and other proteins between neurons using...UCSD bioengineers use computer model to predict evolution of bacteria
... To date, Palsson has created in silico models of metabolism for E-coli, the red blood cell, H. influenzae, H. pylori and yeast. Palsson's lab is one of the few in the country to build a complete network of the circuitry in given cells. Other researchers in the field are describing simple control modules wi...New UGA study demonstrates bacterial pathogens use hydrogen as energy source in animals
...eted as an unneeded waste product, with no role in metabolism or cell growth. Maier resolved to find out once and for all where such hydrogen might be, so he inserted a tiny probe into the stomachs of living mice and measured the amounts of hydrogen in the area of the animals' mucosal layer. The result was star...U.S.-German research consortium sequences genome of versatile soil microbe
...ome paper sheds light on the complex and versatile metabolism that gives P. putida an important role in laboratory research on soil bacteria and also gives the bacterium great potential for bioremediation and other uses. TIGR's German collaborators in the sequencing project were the Medizinische Hochschule Hann...JCI Table of Contents, December 2, 2002
... have examined the effects of thiscytokine on bone metabolism in ovariectomized mice. Their findings (pages16431650) suggest a critical role for IL-7 in the uncoupling of boneresorption from bone formation. High IL-7 levels promote osteoclastogenesison one hand, and inhibit osteoblast differentiation and activi...Psychiatry receives grant establishing Conte Center to study molecular and cellular mood mechanisms
... is investigating the role of tissue nutrition and metabolism in the regulation of mood and motivation. Dr. Masashi Yanagisawa, professor of molecular genetics, is conducting research into the role of appetitive peptides in mood and motivation. The work concentrates on three peptides melanocortin (a-MHS), orex...Supervised exercise program is an effective remedy for cramping leg pain
... blood that reaches the limbs, it increases muscle metabolism and endothelial function, which regulates blood vessels' ability to expand and contract. There also appear to be improvements in blood flow, allowing more blood to reach muscle cells, and a reduction in systemic inflammation. Another benefit is a m...Too much grape juice could cause iron deficiency
... and decreased immune function, among others. Iron metabolism differs among individuals. For the best advice on addressing the specific nutritional needs of children and adults, see a doctor or nutritionist....URI biologists study predator-prey relationship between sand shrimp and flounder
...temperature seems to be the culprit, elevating the metabolism and consumption rate of predators that feast on the juvenile flounder. One predator that seems to be making a negative impact on the survival of flounder is the sand shrimp. URI Graduate School of Oceanography (GSO) professor Jeremy Collie has recei...JCI table of contents, December 15, 2002
...a (CGRPa), however the role of thispeptide in bone metabolism has not been clearly defined. To better understand the role of calcitonin and CGRP-a in bone metabolismRobert Gagel and colleagues at the University of Texas M.D. Anderson CancerCenter, USA, created mice in which the CT/CGRP gene had been deleted. Gi...Increased bone mass in a calcitonin knockout mouse full of surprises
...a (CGRPa), however the role of thispeptide in bone metabolism has not been clearly defined. To better understand the role of calcitonin and CGRP-a in bone metabolismRobert Gagel and colleagues at the University of Texas M.D. Anderson CancerCenter, USA, created mice in which the CT/CGRP gene had been deleted. Gi...