Fullerene-Based Materials Clear From Tissue, Go To The Bone
...dying distribution of the material in mice and its metabolism in rats. Wilson and Cagle showed that radioactive fullerenes stay in the bloodfor over an hour, an advantage for imaging the circulatory system. They alsoshowed that the material localizes in the spleen, kidneys and liver, but withslow and s...... of homocysteine, anatural byproduct of the body's metabolism of food. Several previous studieshave linked high blood levels of homocysteine with increased risk for heartattack and stroke. In the body, folate and other B vitamins break down homocysteine. Therefore,high blood levels of folate, found naturally i...The Sagan criteria for life revisited
...n equilibrium. Biological action such as bacterial metabolism in bogs replenishes the supply. 4. modulated narrowband radio transmissions. These emissions look nothing like natural sources of radio waves like lightning and plasma instabilities in Earth's magnetosphere. They are clear signs of a technological ...Researchers Learn How Nature Produces Cholesterol-Lowering Lovastatin
...ndings may also be usedto genetically alter fungus metabolism to yield more potent drugs. Bacteria andfungi produce hundreds of substances like lovastatin, designed to improve theodds of their own survival. Many of the substances, called polyketides, appearas attractive or repellent aromas, flavors, colors or t...Vitamin C levels linked to amount of lead in blood
... smokingdecreases the absorption and increases the metabolism of vitamin C, higherdietary vitamin C intake levels are recommended. According to Simon, there are no acceptable levels of lead in humans. Symptomsof acute lead poisoning in adults include loss of appetite, abdominal pain,renal (kidney) disease, a...Gene alterations may predict response to new cancer therapy
...n is also important for the metabolism of fats and sugars bycells. The study was published in a recent issue of MolecularCell. Eng, who is director of the Clinical Cancer GeneticsProgram at the Arthur G. James Cancer H...Warner-Lambert Company gift creates bioinformatics program
...tic variationinteracts with behavior, environment, metabolism and diet." "The Human Genome Project and advances in molecular biology have generated aflood of new data about individual components of cells," said Michael A.Savageau, professor of microbiology and immunology in the U-M Medical School anddirector of...OHSU scientists locate 'fat thermostat' in brain
...ctualneurons involved in coordinating appetite and metabolism control in the brainmay have been identified. Rog... there is much more to be learned about the body's metabolism controls,this research could lead to medications that can be used to help regulate apatient's weight...Millennium and the Whitehead Institute identify novel protein important in fat absorption
...s into the body is a key stepin the absorption and metabolism of dietary fat and its conversion to body fat,"said Lou Tartaglia, Ph.D., senior director of metabolic disease at Millennium."The identification of the intestinal fatty acid transport protein provides newinsight into the molecular and biochemical pat...Stressed-out mice offer clues to depression, anxiety, anorexia
...aseof other stress hormones, as well as changes in metabolism and behavior. Male mice without the gene for CRH-binding protein gained less weight and showedmore anxiety-like behavior than littermates that could produce the protein. "These mice exhibit anxiety-like behavior all the time---not just in response to...Researchers characterize mollusk insulin gene, find unique peptide
...ged theglucose level in Aplysia -- thus regulating metabolism -- as had beenanticipated. "But this is just one piece in a very large puzzle," Sweedler said. "Previousstudies have shown that injecting human insulin into Aplysia causes the snail togo into egg-laying behavior. Some of our future work will focus ...FDA mandate for folic acid fortification may decrease the incidence of Down syndrome
...e often have the samegenetic abnormality in folate metabolism associated with spina bifida. The study suggests that the FDA's mandate to fortify foods with folic acidmay have additional long-term health benefits. Says lead author S. Jill James, PhD, at the FDA-National Center for Toxicological Research, "Ourpre...Scientists develop assay for heart disease risk
...sease control a variety of body functions, fromfat metabolism to blood pressure regulation. Each of these genes has variationsthat may represent greater or lesser risk for heart disease. Cheng andcolleagues attached probes for 70 of these gene variations onto nylon strips. They then passed individuals' DNA th...Significant health benefits of a daily fish meal as part of a weight loss regimen
...le alsohaving a beneficial effect on their glucose metabolism and promoting successfulweight loss. The critical, and positive, difference with this specific regimenwas that the fish meals were part of a relatively low fat diet (30% or less ofcalories from fat), while in a previous study the fat content of the ...Substance used to treat complications from diabetes also proves to work as antioxidant
...n and head of the clinical bio-chemistry and human metabolism section. "Alpha-lipoic acid is better than vitamin E at inhibiting protein oxidation." Protein oxidation has been implicated in aging and heart disease. Since alpha-lipoic acid is both fat- and water-soluble, it could prove to be more potent than oth...Rheumatoid arthritis: Olive oil and cooked vegetables may help
...o get most of their polyunsaturated fatty acids by metabolism of the olive oil in their diets. Linos A et al. Dietary factors in relation to rheumatoid arthritis: a role for olive oil and cooked vegetables? Am J Clin Nutr 1999; 70: 1077-82....Another small cog in the 'hub' of metabolism unraveled
...arate reductase. It plays an important role in the metabolism of anaerobic bacteria. Scientists at the Max Planck Institute of Biophysics and at the Institute of Microbiology, J. W. Goethe University in Frankfurt, Germany, have obtained suitable crystals of this enzyme from the anaerobic bacterium Wolinella suc...Most highly endowed promotion prize for fourteen scientists and scholars
...search into the molecular biology of cellular iron metabolism Hentze has discovered important regulatory processes based on controlling the formation of the receptors regulating the uptake and storage of iron. Hentze was the first person to conduct a systematic study of metabolic regulation through control of s...Brookhaven lab collaboration determines how aging affects brain chemistry
...hemical associated with pleasure and reward, slows metabolism in regions of the brain that are related to cognit...ne D2 receptors decreased, so did regional glucose metabolism in areas of the brain that are related to cognition. In the group of healthy participants, glucose m...