University of Pittsburgh research may lead to new therapies for diabetes
...dicine, chief of the division of endocrinology and metabolism and senior author of the paper. "These studies de...rch associate in the division of endocrinology and metabolism and principal investigator. Among the findings were: Blood glucose concentrations were sig......ack on the matter. Florant, who specializes in the metabolism of hibernating animals, has been studying American...ontinue his investigation of fat and prostaglandin metabolism in mammals, particularly alpine marmots. Working with Walter Arnold, director of Vienna University's...Toxicologists discover traces of diesel exhaust in the body
...haled, hygiene when dealing with dusty objects and metabolism differ in each individual. Air samples taken in Vienna have shown that between 12% and 30% of the larger particles contained in air consist of soot particles from diesel exhaust fumes. The WHO has designated such particles as "suspected of causing...Bacterial strain may help clean up harmful industrial waste
...ano studies how the bacterial strain regulates its metabolism of toluene by testing T1 on pyruvate, a carbon sub...in is grown on pyruvate, the genes responsible for metabolism don't switch on, unlike the activity seen when the bacterial strain is bred on toluene. Even if Cos...Acid-loving microbe may be a key to mine pollution
...hip between microbes and minerals. "The organism's metabolism greatly accelerates the acid mine drainage process" by converting the solid sulfide mineral to sulfuric acid, a corrosive liquid that leaches from mining sites into the surrounding environment. The process has caused billions of dollars in damage to ...News briefing: Foods of the future: Selecting and designing foods for a healthy 2025
... Human genetic defects impair food digestion and metabolism WHAT: Foods of the Future WHEN: Monday, March 27, 11 a.m. (PST) WHERE: Moscone Convention Center 747 Howard Street, Esplanade Level Room 114 REPORTERS COVERING THIS EVENT MUST FIRST CONTACT THE ACS PRESS OFFICE AT THE MOSCONE CONVENT...$11-million grant supports study of how genes affect cancer chemotherapy
...tanding variation in the genes that control drug metabolism and toxicity will improve dosing, increase the be...al trial to test whether other drugs can alter the metabolism of CPT-11, allowing higher doses with fewer side effects. Relling is an experienced pharmacologis......nce of the strokes. Increases in cerebral glucose metabolism as measured by PET scanning appeared to correlate with functional improvement." The implanted human neuronal cells are provided by Layton BioScience, Inc., located in Atherton, Calif. LBS-Neurons originate from a human teratocarcinoma, a tumor......versity in East Lansing have manipulated the bugs' metabolism to convert them into tiny powerhouses. They have built a 0.6 volt biofuel cell that can deliver currents of up to 17 milliamperes. Bacteria normally break down glucose to generate adenosine triphosphate -- the main energy source for cells. This in...New Gladstone/UCSF study finds inhibiting fat synthesis results in obesity resistance in mice
...ey were more active. DGAT-deficiency also affected metabolism in other tissues, including causing an impairment in milk production in females. "Our findings indicate that multiple mechanisms exist for triglyceride synthesis, rather than a single mechanism as previously thought. They also suggest that specifica...Microbes on Earth may be key to identifying life on other planets
...f Illinois. "By studying the effects of microbial metabolism on the chemistry of the water and on the way minerals are deposited in Earth environments, we can better interpret samples from other planets for signs of life." For example, various carbonate features -- including tiny, rod-shaped calcite crystals -...Pouch's newfound role tied to potential new treatment for malaria
...ed diseases -- have "potent effects" in disrupting metabolism in two other parasites (toxoplasma and trypanosomes). "We believe that pyrophosphate analogs concentrate into these acidic calcium organelles and become toxic against the parasite but not the other host cells," Docampo said. "Since acidocalcisomes a...... to diabetes, which is principally a defect in the metabolism of sugars and fats."...Honey : Natures's sweetener may increase recuperation after workouts
...oted favorable changes in post-exercise markers of metabolism equal to that of the current standard, maltodextrin," says Dr. Richard Kreider, lead investigator of the study and Director of the Exercise and Sport Nutrition Laboratory at the University of Memphis. "We also found that the group receiving honey as...Researchers announce first preimplantation genetic diagnosis for a rare inherited disease
...ely one in 70,000 births. Babies with OTCD have a metabolism which is unable to break down protein effectively. This results in hyperammonemia (an excess of ammonia) which causes death. If detected and treated immediately after birth, a baby may live for longer, but death can occur unexpectedly at any time. ...MetaPhore reports general anti-inflammatory surface treatment for biomedical materials
... Superoxide is a free radical arising from oxygen metabolism in activated white cells. SOD catalyses the removal of superoxide radicals providing a major protective effect in our bodies. Unlike the natural enzyme, the mimic of SOD is well suited for use as a protective surface treatment for biomaterials becau...Compound that switches off appetite in mice discovered by Hopkins scientists
...nces. If you try to lose weight by starving, your metabolism slows down after a few days: It's a survival mecha...the team's 14-year exploration of the abnormal fat metabolism that exists in many cancer cells. "Breast, prostate and cancer cells, for example, make a lot of fa...Boston University scientists uncover the secret to movement in super-cooled water
... pace - like a hibernating bear. Essential to this metabolism is the fact that water can exist in a viscous state, not just as the liquid we are familiar with, nor frozen (which would block all metabolism), but in the super-cooled state that scientists describe as glassy. Understanding just how these molecules ...Women with low body iron find exercise harder
...omen, the lack of iron has an effect at the muscle metabolism level," explains Hinton, whose co-authors at Cornell, besides Haas, were Christina Giordano '98 and now a medical student and Thomas Brownlie, M.S. '99, and now a Cornell doctoral student. To prevent iron depletion, the researchers recommend red mea......er understand the genetic determinants of obesity, metabolism and the regulation of fat mass, which have been poorly understood in the past. In the future, this type of research will lead to new drugs to treat obesity and will help endocrinologists and other doctors who treat patients suffering from obesity to ...