Tag: "metabolism" at biology news
... 166, p R11). "It's crucial for the proper metabolism
of the body's hormones, synthetic steroids and many drugs," says Krishna Chatterjee of Cambridge University. But if levels of the enzyme are too high, drugs are broken down too fast to be effective. Production of CYP3A is boost...
Researchers find key to tuberculosis persistence in the body
...ggested that M. tuberculosis reprograms its carbon metabolism
in response to the activation of certain immune ce...une response of the host dictates the basic carbon metabolism
of the pathogen," McKinney says. "I don't know of any precedent for this in the literature." A separ...
Deadly for bacteria, great for consumers
...y take away electrons needed by cell membranes for metabolism
and survival. "We think the main indicator of the effectiveness of the solution is the oxidation-reduction potential," says Hung. "When you compare chlorinated water with electrolyzed water, there is a difference in the oxidation-reduction potent...
Alcohol and the human fetal brain
The first step in the metabolism
of alcohol is its conversion to acetaldehyde (AcHO... & Experimental Research , scientists compared the metabolism
of alcohol in prenatal human brain and liver tissue with the metabolism
in both prenatal and adult r...
Nutrient in cruciferous vegetables protects against lung cancer in study of 18,244 Chinese; benefit depends on genetic factor
...ease risk of lung cancer. Among those lacking the metabolism
enzyme, a 64% decrease was noted. Precursors of ITCs, a class of naturally occurring chemicals, are released when cruciferous vegetables are chewed and the anticarcinogenic isothiocyanates are formed. The study appearing in the journal Lancet (Vol...
Researchers discover major diabetes susceptibility gene
...series of metabolic abnormalities, including lower metabolism
and increased insulin resistance, that resemble mild diabetes. These metabolic effects are strikingly consistent with a 30-year-old theory that certain ethnic groups have evolved "thrifty" genes, which have historically protected them in times of ...
What are 'life-style' genes?
...sekeeping' genes carrying out/performing the vital metabolism
of the cells. The other mostly contains 'life-style' genes, which are tailored to suit a specific environment and are shared between the organisms within one ecological niche. Complete deciphering of the Thermoplasma acidophilum genome is a prere...
Researchers prevent obesity and diabetes in mice
... work suggests that it is possible to alter muscle metabolism
and body weight in animals by producing this protein in muscle. "We've produced mice that can eat as much as they like without suffering the consequences of obesity and diabetes," says Clay Semenkovich, M.D., professor of medicine and of cell biolo...
Searching for new medications to treat alcoholism
...the liver to metabolize naltrexone." The variable metabolism
of naltrexone in individuals may explain why the medication doesn't work for everyone. Treatments for alcohol dependence have helped scientists understand more about the biology of this brain disorder. First and foremost, as noted by Raymond Anto...
Feds give $16 million to UNC-CH scientists studying waste site problems
...genotyping to examine the effect of DNA repair and metabolism
genes on susceptibility to diseases linked to toxic chemicals. The mathematical modeling core will assist all investigators with advanced modeling and statistical analysis. "Over the past nine years, we've trained about 110 graduate students and 40...
Global warming: lessons taught by snails and crabs
...nger make proteins - the molecules responsible for metabolism
- then its survival is in jeopardy. Therefore, additional warming could create serious problems for both snail species.`` Ever northward These experiments may help to explain why so many marine invertebrates, once common in Monterey Bay, have becom...
Unified theory relates microbial metabolism to lab and field
...oratory experiments to better understand microbial metabolism
in nature. "The growth of microbial populations ca...s of chemiosmotic theory."In our approach, a cells metabolism
is represented by a multi-step, enzymatically catalyzed reaction that is directly coupled to energy ...
Millennium's LDP(PS)-341 inhibits growth and induces death of cancer cells, appears to overcome chemotherapy resistance
...41's novel mechanism of action and its role in the metabolism
of a variety of proteins with critical cell function make it a promising candidate for the treatment of cancer. "Proteasome inhibition is a prime strategy for developing new therapeutic agents to combat solid tumor and hematologic cancers, such as m...
Voyage of the space veggies
... add a few tricks to allow humans to control plant metabolism
remotely. And for good measure, they envision implanting minuscule electronic sensors to collect data on the plants' health, so humans can intervene before something goes drastically wrong. It is a tall order, but the group has some time to work it ...
Science's Top 10: genome sequencing named top scientific advance of 2000
...uctures that mediate processes such as cholesterol metabolism
and fatty acid production, and implicating others in diseases such as diabetes and certain types of cancer. This year's bumper crop of nuclear hormone receptor discoveries could lead to new targets and treatments for some of these diseases. Researche...
Two bees or not two bees? Researchers take first look at the genetic differences between queen and worker honeybees
...ste-related genes, including genes responsible for metabolism
and respiration. Worker bees, they found, continued to express more of the genes typical of the juvenile larva. This difference in gene expression is thought to lead to a difference in the size and function of organs that gives the upper hand to quee...
Enzyme is crucial for production of plant growth hormone
... these mammalian enzymes should look at tryptophan metabolism
as one of the important physiological roles for these enzymes."...
Different effects of puberty on resting metabolism in white and African American children
...limbs, but lower lean mass in the trunk. Since the metabolism
of organ tissue in the trunk represents the major ...anovski questions whether the observed slowdown in metabolism
during puberty is transient, as are many other humoral factors during this stage of life. However, t...
Mouse with iron disorder offers clues to Parkinson's, similar diseases
Mice engineered to lack a gene involved in iron metabolism
may provide important clues for deciphering the na...finding suggests that other genes involved in iron metabolism
may be good candidates for investigations into the causes of these disorders. In addition, the b...
A persimmon a day could be better for your heart than an apple
... researchers showed that persimmons improved lipid metabolism
in rats. Many persimmons contained twice as much dietary fiber as apples. The peels of both fruits had higher fiber levels than the pulp or the whole fruit, according to the findings. Persimmons also contained more of the major phenolics (antioxidant...
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