Extreme climate variance sped extinction of local butterfly populations, researchers say
...o into a resting stage called diapause, when their metabolism shuts down for the summer. "The biggest source of mortality for the butterflies is failure to get big enough to go into diapause before the plant vanishes," Boggs says. When the rains come in November, the caterpillars begin feeding again. Now they a...Researchers find new genetic influences on alcohol metabolism
... her brain after drinking is related to his or her metabolism of alcohol. In other words, two people may drink ...e same amount of alcohol, but differences in their metabolism could make one individual more intoxicated than the other. A study in the May issue of Alcoholism:...New research questions evidence for earliest life on earth
...While fossil shapes cannot be seen, the process of metabolism in living organisms separates different weights of carbon, leaving what has been thought to be a unique chemical "fingerprint" of past life. However, the article by Christopher Fedo, from The George Washington University's Department of Earth and Env...Applied Biosystems introduces new system for protein and metabolite analysis
...iscovery researchers analyzing small molecule drug metabolism and ADME - absorption, distribution, metabolism and excretion - are expected to be able to both rapidly identify and quantitate a broad range of met...Society for Women's Health Research News Service to provide series on women and pharmacology
... the first article covers sex differences and drug metabolism and is available at www.womens-health.org/press/N...lowing topics: June 24: Sex differences and drug metabolism July 11: What are me-too drugs and why are they necessary? July 25: Understanding generics August 8:...Penn State College of Medicine researchers correct scientific theory about how gene switch works
...ribes the way the gene switch regulating galactose metabolism operates. These findings offer a new set of param...ive galactose pathway genes give rise to galactose metabolism problems," Hopper said. Previously, it was thought by scientists that GAL3p was found only in the nu...Clues to the evolution of photosynthesis
...lved in the pathways for phytosynthesis and in the metabolism of sulfur and nitrogen. "These duplication events may help explain why this microbe is able to use lower levels of light to carry out photosynthesis than other species," said Eisen, the first author of the PNAS paper. Another reason why biologists st...Monkeys that drink heavily develop signs of liver disease, Wake Forest study shows
...dative damage" to the liver. He explained that the metabolism of alcohol in the liver generates "reactive oxygen" which can damage liver tissue. To track that, they chose to follow damage to lipids, since cell structure is influenced by lipids. The damaged liver produces isoprostanes in the urine -- tiny piece...Researchers discover molecular 'switch' that tells body to store or burn fat
...s as a nutritional signal to regulate body weight, metabolism and other physiologic processes. Since the discove...e enzyme's activity as in asebia mice could alter metabolism without incurring unwanted side effects. The answer appears to be yes, according to Ntambi and co-au...Research identifies enzyme involved in fat storage
...rs pursuing the cause of leptin's ability to boost metabolism and shed fat have identified a metabolic switch th...strate that SCD-1 is a key to leptin-regulated fat metabolism in the liver. However, he said that additional studies would be needed to understand how the enzyme ...Rare childhood bone disorder linked to gene deletion in two Navajo patients
...ile Paget's disease (JPD), an extremely rare, bone metabolism disorder. Now, researchers at Washington Universit...of JPD, but also shed light on the control of bone metabolism in general," says lead investigator Michael P. Whyte, M.D., professor of medicine, genetics, and ped...Research to estimate pesticides' effects on children
...chemicals because of their developing organs, high metabolism and high skin-surface-area-to-body-weight ratio. "In a growing body, cellular membranes are expanding. As a result, toxic chemicals readily pass through those membranes," Leckie observed. "Also, biochemical pathways in children are not complete yet ...Antioxidant protects islet cells used in transplants for diabetes
...islet cells that secrete insulin necessary for the metabolism of sugar. Many diabetes patients take insulin shots to make up for the lost islet cells. In 2000, researchers from Edmonton, Alberta, reported new techniques that have made islet-cell transplantation a promising option for patients with type 1 diabet...Genetic markers key to identifying schizophrenic patients who can benefit from clozapine
...ug metabolizing enzymes: Antipsychotic medication metabolism is primarily mediated by the cytochrome P450 (CYP)...phisms confer certain types of differences in drug metabolism for clozapine, which results in extensive metabolizers (EM) for 75-85 percent of the population, poo...Mice provide insight into bone metabolism disorders
...lts not only provide insight into diseases of bone metabolism such as osteoporosis, but the mouse strain used in the study also may be the first animal model of a rare genetic disease called juvenile Paget's disease (JPD). "Our findings are important for understanding how bone forms and breaks down, and how tho...Tips from the Journals of the American Society for Microbiology
...h status will advance our understanding of oxalate metabolism in the human gastrointestinal tract, and may ultimately provide practical approaches for the prevention or alleviation of hyperoxaluria," say the researchers. (S.H. Duncan, A.J. Richardson, P. Kaul, R.P. Holmes, M.J. Allison and C.S. Stewart. 2002. ...UW scientists find genetic pathway to potent anticancer agents
...r the enediynes' reactivity, and address issues of metabolism and production."...Transplantation Society Congress
...ant in a mothers uterus to treat a baby with liver metabolism problems Cells from discarded livers became stem cells that in bioartificial device stabilized patients with acute liver disease until liver transplantation was possible, reports German study Both pig and stem cells could hold answers for treating ...A message from nature to muskrats: 'Dont chill out'
... duration that can be supported by an oxygen-based metabolism (accessible body oxygen stores divided by the rate...ooled tissues. Essentially, this effect depresses metabolism of cooled body tissues, thereby conserving energy. Cooling the body to increase diving time is know...Actonel significantly reduced moderate and severe vertebral fractures
...alcemia and other disturbances of bone and mineral metabolism should be effectively treated before starting Actonel therapy. Actonel is not recommended for use in patients with severe renal impairment (creatinine clearance < 30 mL/min). Bisphosphonates may cause upper gastrointestinal d...