Uterine Environment Boosts Learning Ability In Mouse Offspring
...pus-like autoimmunediseases and such conditions in mice as neocortical ectopias similar to thosefound in t...er groups. But the Out-Strain groupof hybrid-uteri mice demonstrated significant cognitive advantages over theother groups and better adaptation to all expe...Study Shows: Just Say NO To Bone Loss
...y associatedwith nerve tissues. A recent study on mice with the NO neuronal synthase geneknocked out reported extremely aggressive male mice that were overly sexuallyaggressive. A third form is inducible NO synthase, the kind involved in bo...Study Links Viruses And Vascular Diseases
...eir own." Damage resembles human diseases Normal mice never develop full-blown atherosclerosis, which ma...ontroversial." Intriguingly, infections in newborn mice led to fatal vascular disease when theanimals were well into adulthood. "The infection doesn't cause...MIT's Mini Respirator Breathes Life Into Mutant Mice
...to treathuman polio patients, was built for mutant mice suffering from respiratorydistress. These animals,...inary tests of the machine with one kind of mutant mice arepromising. The ventilated mice survived over 50 percent longer than the absolutelife expectancy o......brafish vestibular/auditory mutants are similar to mice shaker/waltzer type mutants in that they also make circular motions and have problems with maintaining balance. Behavioral tests suggest that some of these zebrafish mutants do not sense gravity, i.e. they swim as if they are in a weig...Mouse Gene Reveals Clues To Human Deafness
...milies. Although the evolutionary paths of mice and humans diverged millions ofyears ago, segments of their chromosomes contain the same genes. The comparisonled the geneticists to a mouse gene known to be crucial for normal developmentof mouse hearing. When the human form of the same gene was s...Peptides Implicated In Body's Response To Pain
...SF) and the University of Minnesotahave found that mice with a mutation in a gene that encodes for two che...when glutamate receptors are blocked, experimental mice exhibit a reductionin their responses to pain, providing scientists with compelling evidence of thec...Pitt Researchers Develop Strategy To Use Dendritic Cells To Treat And Prevent Tumors
...effectively prevented tumor development in healthy mice and reduced tumors in 80percent of mice with established tumors, significantly prolonging theirsurvival. "Not only is this approach ...Link Made Between Human Growth Hormone, Bone Quality In Mice
... cross-sections of bone inexperimental and control mice is available on request. ANN ARBOR---Laboratory mice which have been genetically altered to produce humangrowth hormone grow to be 25-30 percent larger t...Researchers Discover Ways The Ulcer/Cancer Bug Can Trigger Disease
...served as normal controls. Both groups of mice were exposed to H. pylori strains retrieved fromPe...le to bind to Leb.Guruge found that both groups of mice -- those with and those without Leb --became infected with H. pylori easily and for long periods of ...Possible Trigger For Heart Failure Identified In Lab Animal Studies
...The Dallas scientists demonstrated that laboratory mice who weregenetically altered so their heart cells p...udy, researchers developed two lines of transgenic mice whichexpressed TNF in the heart. The two lines, which included 30 mice, diedprematurely of heart fa...Obscure Enzyme May Play Major Role In Heart Disease
...tionship. In experiments with a strain of mice that are vulnerable toatherosclerosis, an inverse ...erosclerotic lesions in the blood vessels of these mice was found to berelated to the reduction in paraoxonase activity. The next step, Aviram sai...Researchers Discover Existing Drugs May Prevent Enlarged Hearts
...blished in the April 17 issue of Cell, was done in mice whoseprogression from cardiac hypertrophy to heart... researchers genetically engineered two strains of mice totest their hypotheses. One strain continually expressed activatedcalcineurin in heart muscle cells...Researchers Identify Protein Critical To Urine Concentration
...Francisco researchers have identified a protein in mice that is essential for enabling the kidneys to form...s found widely in animals. They then deprived the mice of water. Within 36 hours, these mice had become severely dehydrated and lethargic, had lost substa...Duke Researchers Genetically Engineer Mice To Block Heart Enlargement
...iversity Medical Center havegenetically engineered mice to produce a protein that acts as a molecular deco...decoy into mouse embryos. The resulting transgenic mice made the decoy proteinin their heart cells. Then the researchers induced pressure ove...Electron Accelerator Provides Unique Proof Of Gene Repair Process In Living Cells
...f the four proteins, and produced mutant yeast and mice to study the way an inability to repair genes may lead to cancer. For the experiment reported in Science, Petrini enlisted the help of UW-Madison physicists and engineers who work at the university's Synchrotron Radiation Center, where high-speed pr......St. Louis now haveoffered a solution by generating mice that make only human apoE3 or human apoE4.Their experiments with these mice show that apoE3 promotes nerve cell outgrowth,whereas apoE4 does not. Most people have eithe...A Cup Of Tea May Protect Against Skin Cancer
...ultraviolet (UV) rays. The latest research with mice found those given tea (with milk) experienced a r...t reduction in the development of skin cancers in mice drinking tea with milk. "These findings are significant because initially it was thought milk m...Pediatric Academic Societies Report Progress In Children's Health
...sity of Pennsylvania School of Medicine.Working in mice bred to lack a gene that causes a rare but serious metabolicdisorder called Ornithine Transcarbamylase Deficiency (OTCD), the researcherssucceeded in injecting normal copies of the OTC gene into the bloodstream, wherethe new gene served as a bluepri......est indicates the pigment functions normally inthe mice and the gene is transferable from one generation t...Santa Barbara. Creation of the transgenic mice will give scientists a new vehicle forstudying human vision problems, as well as a tool for investig...