Heat-loving Microbe Repairs Its DNA With Light
A University of Cincinnati biologist has found a microbe whichnot only survives under extremely hot and aci... decompose. So, Groganhas been looking at how this microbe managed to protect itself. "Since the precise structure of DNA is essential for life and reproduct...... totrace energy flow through the food web from the microbe producersthrough the intermediate grazers to the carnivores at the top ofthe food web. "All the data show quite clearly that these animals are basedon chemoautotrophic carbon production. They don't eat any foodthat comes from the surface," said Sarbu...Researchers Find How Disease-resistant Plants Recognize Bacteria
...stant to certain diseases, but the disease-causing microbe evolves and the resistance breaks down. By learnin...onary "why" remains a strange mystery: Why would a microbe have a dominant gene that allows it to be recognized and repressed by its host? "It's as if the path...Munching Microbes Make A Meal Out Of Toxic Substances
... conclusion is that there are more of this type of microbe at these sites because they're eating one of their favorite foods -- petroleum," Nies says. The standard method for cleaning up contaminated soil is to excavate it and truck it to a landfill, which not only costs more than bioremediation, but also is...Chemists Develop High-Throughput Method To Synthesize And Screen Novel Antibiotics
...f bacteria, and against a"defanged" version of the microbe that causes tuberculosis. The results were encouraging, although Day knows thesecompounds have a long way to go before any of them could reachhuman testing. "We can make beta lactams that take out thetuberculosis bacteria without any trouble, but th...Hurdle In Ulcer Vaccine Development Cleared
...ed andisolated a bacterial protein that allows the microbe to cling. "With this attachment protein in hand, it eventually should be possibleto develop a vaccine against peptic ulcers and gastric cancer," says ThomasBorén, D.D.S., Ph.D., an assistant professor of oral biology at Umeå Univers...Women Younger Than 30 Need To Be Screened For Chlamydia
...t that is more sensitivethan previoustests for the microbe that causes the disease, Chlamydia trachomatis, saysQuinn. In their studyof 7,699 women at two family planning clinics in Baltimore, the Hopkins teamfound thatscreening all asymptomatic women under 30 was more effective than either of twootherstrat...Study Of Microbes May Hone Predictions Of Mining Impact
...e the mine, making up as much as 50 percent of all microbe species found in a vast network of underground tunnels. The Wisconsin team explored two important environments at Iron Mountain where mining occurred both in above ground pits and in miles of tunnels below ground. "There are two different types of ...Eviction From Scum Home Makes Disease-Causing Microbe Vulnerable
... has found a chink in the armor ofan opportunistic microbe that is a top cause of infections inhospitals. By genetically altering the bacteria Pseudomonasaeruginosa, the team was able to break up the colonies thatnormally make the germ resistant to detergents and antibiotics.The work relies on mucking up the...Jellyfish Help To Make Sugar Smarter
...ctive where genes are being transferred using the microbe Agrobacterium. It is also non-toxic." All the researchers have to do to see if the jellyfish gene is working is shine a blue or ultraviolet light on plant cells containing it and watch through a microscope equipped with a special filter to see i...New Vancomycin Structure May Point To Path For Overcoming Antibiotic Resistance
...garnered its capability from another, lessvirulent microbe called enterococcus. Given the fast-paced global spread of theresistant staph -- the first case in the world occurred only in May of lastyear, in Japan -- there is reason to fear the proliferation of bacteriaunresponsive to vancomycin and other curre...University Of Cincinnati Biologists Find Evidence For Unusual DNA Repair InArchaea
...pH of about 3. They know very littleelse about the microbe or any other member of the archaea, the so-called ...s . In previous work, Grogan demonstrated that the microbe can usevisible light to repair DNA damaged by ultraviolet light. Now, he is searching for tools tost...Scientists Identify Molecular Target For Tuberculosis Drug Treatment
...e identified the exact part of the disease-causing microbe thatis targeted by isoniazid, the most widely used TB medication. Tuberculosis now infects some 1.9 billion people worldwide, one-third of theworld's population. The World Health Organization projects that in the nextdecade, 300 million more people ...Relapsing Fever Spirochete Switches Surface Proteins When It Changes Hosts
...tick-specific protein gets turned off againand the microbe again produces that very same variable membrane protein that wasbeing produced when the tick ingested it." Decreasing the temperature, the RML scientists discovered, can trigger thechange. "One likely cue that promotes this switch is the drop in t..."A Little Bit Here" And "A Little Bit There" Can Add Up To A Big Problem
...g in humans, and outbreaks ofPfiesteria, the toxic microbe that has plagued mid-Atlantic waterways. The report lays out several steps that can be taken to help ease nonpoint sourcepollution. Landscape management and restoration, including vegetation buffersalong waterways and wetlands restoration, can great...Security Code Helps Immune Cells Attack Foe And Spare Self
...ey make the appropriate response. Theymay kill the microbe directly, help a killer T-cell dispose of a virus-infectedcell or stimulate immune cells that manufacture antibodies. Helper cells use receptors on their surface to read antigenic displays.But instead of getting close enough to get a really ...Feed A Microbe An Unearthly Dish And You Make Your Own Extraterrestrial
... so he and histeam decided to see if a terrestrial microbe could adapt to a major change inits diet. They grew a strain of the bacterium Escherichia coli that can't make theamino acid tryptophan, an essential part of proteins. As a result, it requires aconstant supply of tryptophan to grow. ...A Common Microbe Could Help To Trigger Alzheimers
...s Protect You From Alzheimer's Disease? A COMMON microbe could help to trigger Alzheimer's disease, say res...rethink on how to preventthe disease. The microbe in question is Chlamydia pneumoniae, which is spread bycoughs and sneezes. By the age of 20, half th......a vaccine againstHaemophilus influenzae b (Hib), a microbe that causes bacterialmeningitis and other diseases. The bacterium used to infect about20,000 children in the United States alone each year, killingmore than 1,000 and leaving thousands of youngsters deaf, blind,paralyzed, or with mental retardation. ......to assess the effects of severeconditions on their microbe samples, and to learn how these conditions compare...nals called thermal shockproteins that trigger the microbe to protect itself against extremes in heat andcold. Two types of containers will be used. One will p...