Tag: "microscopy" at biology news
JCI table of contents September 15, 2004
...ing two-photon molecular excitation laser scanning microscopy
(pages 775783). Synchronous intracellular calcium transients occurred primarily only in host cardiomyocytes, but did also occur in a small fraction of donor-derived myocytes at the graft-host border. EGFP-marked donor myoblasts were transplanted into...
Protein is key to fatal disorder and normal cell function
...urface and protective membrane coating. Time-lapse microscopy
revealed that cln3 moves rapidly back and forth between the Golgi and the cell surface. "It turns out that the cln3 protein may be a crucial protein involved in the transport of vital lipids from the Golgi, where they are made, to where they are need...
Stuck on you: Scientists lay bare secrets of bacterial attachment proteins
...very difficult to see using the available electron microscopy
techniques, and were originally classified as non-fibre or 'afimbrial'. The new key piece of evidence emerged from some nifty protein engineering of the protein subunit, known as AfaE. These subunits make up the fibre and cannot fold properly as prot...
Probing the surface of white blood cells to enhance immune system medicine
...at Dartmouth Medical School used scanning electron microscopy
to analyze the finger-like projections coating white blood cells known as microvilli. "If you asked most medical scientists what a white blood cell looked like they would say a smooth sphere that floats around in the blood, but, in fact, they are not...
Images reveal how rotavirus - leading cause of diarrhea - enters cells
... the researchers used crystallography and electron microscopy
to determine the geometric structure and working p.... Comparison of the crystal structures to electron microscopy
images, obtained by colleagues at the Baylor College of Medicine, suggests that VP4 undergoes two co...
ASU researchers demonstrate new technique that improves the power of atomic force micrscopy
... chemical composition of molecules. "Atomic force microscopy
has a resolution down to an atomic level, but unti...d like Lego blocks, then conventional atomic force microscopy
(AFM) is feeling the Lego blocks on the floor, but it can't tell the difference between one block an...
Shedding new light on biology
...as a major breakthrough in both the scientific and microscopy
communities. "Not only is this microscope simply more powerful than many existing technologies, but it also comes at the perfect time for biologists who need to study complete systems." Ernst Stelzer emphasizes this aspect. "It is extremely valuable ...
The telomere crisis: A crucial stage in breast cancer
... and see if they are similar." Using 3-D confocal microscopy
and working first with breast-cancer tissue samples, at each stage the researchers assessed genomic instability and such correlated features as the amount of DNA content, signs of rearranged chromosomes, and the number of copies of genes known to pla...
UC Riverside researcher takes snapshots of the movement of molecules in a billionth of a second
...n University, Glassboro, NJ. "Scanning probe microscopy
has the capability of reaching directly down to the natural spatial scale of atoms and molecules," Bartels said. "While femtosecond laser techniques have the capability of reaching down to the time scale of atomic events. "There has been consid...
Tips from the Journals of the American Society for Microbiology
... films, commonly referred to as "soap scum," which microscopy
reveals are constituted of lush microbial biofilms," say the researchers. In the study DNA samples were taken from four vinyl shower curtains in different homes. A broad range of RNA gene sequences were revealed with Sphingomonas spp. and Methy...
New textbook introduces students to the foundations, applications of nanotechnology
...es of materials. Nanotechnology was enabled by the microscopy
technologies developed in the 1980s that provide atomic-scale resolution and, later, nanoscale modification of surfaces. The authors describe the top-down approach, or lithography, as "similar to the work of a sculptor carving a face from a block of ...
EC boosts European electron microscopy research
...brings together the leading scientists in electron microscopy
(EM) from seven European countries. The specialists for the various EM-technologies electron tomography, single particle analysis, and electron crystallography will combine their expertise to reach a very ambitious goal: the three-dimensional (3D) im...
Microscopy scans show how brain cells process energy
ITHACA, N.Y. -- A laser-based microscopy
technique may have settled a long-standing debate ...as Alzheimer's, wreak on brain cells. Multi-photon microscopy
scans by Cornell University biophysicists of living brain tissue, as reported in the latest issue of...
Carnegie Mellon U. imaging study reveals sex-based differences that persist as mice enter adulthood
...es of intact mouse brains using magnetic resonance microscopy
(MRM), an extremely high-resolution magnetic resonance imaging (MRI) technique. Carnegie Mellon is one of few groups nationwide with the capability to perform MRM. Koshibu, who did much of the data analysis, recently completed her doctoral work in th...
UNC scientists uncover crucial mechanism for blood vessel development
...rescent protein. This "marker" allows fluorescence microscopy
to visualize living cells. The experiment enabled the researchers to analyze the dynamics of vessel formation in real time by performing time-lapse imaging of live endothelial cells. Using this method they demonstrated that blood vessels made from ce...
3-D micro-imaging technology licensed to Carl Zeiss Jena
... 2004) by Carl Zeiss Jena GmbH, a leading maker of microscopy
instrumentation, and by CCTEC, the technology, ent...rnell University. The license for two-photon laser microscopy
(also known as multiphoton microscopy, and protected by patents dating back to July 23, 1991) has be...
Brain disease research, particle physics meet in the middle (ware)
...uch as MRI brain scans or high-resolution electron microscopy
images is essential to participants research into Alzheimer's disease, depression, schizophrenia, multiple sclerosis and other disorders. With the participating research labs connected by the Internet2 high-performance network, the BIRN cyberinfrast...
Evidence of nanobacterial-like structures found in human calcified arteries and cardiac valves
..., and after decalcification, appeared via electron microscopy
to contain cell walls. The research paper, entitle...dney stones, and observed by transmission electron microscopy
in a calcified human mitral valve." Furthermore, they said they designed their study to systematica...
ORNL's nanobiosensor technology gives new access to living cells molecular processes
...arget molecules of interest inside the cell. Video microscopy
experiments reveal the minimally invasive nature o...o route. Conventional analytical methods--electron microscopy
or introducing dyes, for example--have the disadvantage of being lethal to the cell. "The informatio...
Stretching DNA on a tiny scale, researchers probe the basis for its compaction
Using magnets and video microscopy
to measure the length of individual DNA molecules under experimental conditions, researchers have demonstrated that Condensin, a complex of proteins widely conserved in evolution, physically compacts DNA in a manner dependent on energy from ATP. The ...
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