Controlling cell adhesion: Researchers report first evidence of 'catch bonds'
...r. "These observations confirmed the atomic force microscopy results and reinforced their physiological relevance in an experimental design that recapitulates cell interactions in the circulation." Understanding the phenomenon is important, McEver noted, because the lifetimes of the adhesive bonds determine wh...Scientists at UCSB link brain plaques in Alzheimers disease to eye disease
... meetings covered how the scientists used electron microscopy to examine the organization and distribution of amyloid beta and other drusen-associated molecules....Muscle-repair defect underlies two muscular dystrophies
...ve in other forms of muscular dystrophy. Electron microscopy studies of the dysferlin-knockout mice revealed that the plasma membrane surrounding the muscle fibers showed areas of disruption associated with accumulations of vesicles. These findings strengthened our interest in the possibility that these mice h...Argonne research offers clues to Alzheimer's plaques
...ermining their structure." In addition to electron microscopy studies on the fibrils at the University of Chicago, solid-state nuclear magnetic resonance (NMR) studies were performed at Botto's lab at Argonne. The researchers replaced specific amino acids in the truncated peptide, one at a time, with those cont...Scientists find evidence for crucial root in the history of plant evolution
..., the researchers used scanning transmission X-ray microscopy (STXM, or "stixum"). This involved mounting the fossil impression on a copper grid and bombarding it with a brilliant focused beam of X-rays in the "soft" range between 200-900 electron volts. Biological elements, such as carbon, nitrogen and oxygen...JCI table of contents, March 3, 2003
... colleagues applied real-time, in situfluorescence microscopy in lung capillaries. As they report (page 691-699),pressure elevation increased the amplitude of cytosolic Ca2+ oscillations,which in turn increased the amplitude of mitochondrial Ca2+ oscillations andthe production of reactive oxygen species. P-sele...Never too late to boogie: Nerve cells still active in 'mature' brain
...l Development." Recent advances in high-resolution microscopy and image analysis have made it possible for researchers to "look under the hood of the molecular engine," to view nerve cells and the interaction among components of their basic cytoskeletal structures and among nerve cells in general. Study of the ...UC Riverside receives $1.25 million from W. M. Keck Foundation
...ents the tools of functional genomics, proteomics, microscopy and bioinformatics. These tools will enable the scientists and students to develop the new knowledge needed to control pests and pathogens, solve complex problems in plant biology, increase food production efficiency and analyze genes and proteins o...American Physical Society March Meeting 2003
... headlights (session V7). Magnetic resonance force microscopy (MRFM), the marriage of STM and MRI technology, se...l for nanoextraction, as nanowicks, and for better microscopy (sessions K26, N26, V26, and X26). ULTRAFAST LASER PULSES FOR CLEANER AIR Modern cars often use c...Radiation-resistant organism reveals its defense strategies
...eria. Using an assortment of optical and electron microscopy methods, Prof. Avi Minsky of the Weizmann Institute of Sciences Organic Chemistry Department found that the microbe's DNA is organized in a unique ring that prevents pieces of DNA broken by radiation from floating off into the cell's liquids. Unlike...A drop of ocean water tells a story
...he use of molecular techniques in combination with microscopy now allows for the identification of certain bacteria types. The scientists found that the bacterioplankton SAR 11 comprises as much as 50 percent of the total surface microbial community (from zero to 140 meters below the surface) and 25 percent of ...A new window to view how experiences rewire the brain
...Institute researchers have developed sophisticated microscopy techniques that permit them to watch how the brain...ly forming synapses, the researchers used electron microscopy to analyze in brain slices the same regions that they had studied in the living animals. Those studi...From the bone of a horse, a new idea for aircraft structures
...the horse bone around its hole - or foramen - with microscopy and microradiography, techniques that render the details of its microscopic composition. They converted the resulting information into equations describing the bone's mechanical properties - for example, converting the bone's mineral density and poro...Teamwork in the intestine: Gut bacteria interact with intestine to regulate blood supply
...normal mice. An imaging technique called confocal microscopy provided three-dimensional images of sections of intestinal tissue taken from each group of animals. The images offer a clear view of cells and blood vessels in tissue samples, and allow investigators to measure the density of capillaries, small bloo...Transforming brain research with jellyfish genes and advances in microscopy
... such as low-light-level digital imaging, confocal microscopy and two-photon microscopy, the investigators can o...at interconnect them within the brain. Two-photon microscopy uses a powerful infrared laser that can selectively stimulate the fluorescent proteins within the ne...Scientists identify motor that powers parasitic cell invasion
... the effects on its motility. They used time-lapse microscopy to score the percentage of parasites able to glide and perform normal forms of movement on coated glass slides. "In optimum conditions freshly released parasites exhibit circular gliding, upright twirling and helical gliding. But with only partial ge...High school science teachers translate the latest research into classroom activities, lessons
...tween microbes and minerals using biological force microscopy (BMF), which was developed at Virginia Tech. Such forces can dictate whether minerals are taken out of or released into groundwater, for example. BMF has made it possible to model such interactions. Other researchers are evaluating controls of transp...UCR scientists contribute to study that will help formulate new ways to combat malaria
... studies in genomics, gene expression, proteomics, microscopy and bioinformatics. Research efforts are focused on insect genomics, plant cell biology/genomics, microbial genomics, mammalian genomics and bioinformatics. "A transposable element is a sequence of DNA that is capable of moving around in the genome ...Newly revealed viral structure suggests a continuum in the evolution of viruses
...hers to dissect the structure of PRD1 are electron microscopy and X-ray crystallography. Computer modeling was u...he relatively low-resolution technique of electron microscopy with the high-resolution molecular structure of the coat protein obtained through X-ray crystallogra...Scientists use alfalfa plants to harvest nanoparticles of gold
...croscope work was done at UT-Austin. The UT-Austin microscopy team, directed by chemical engineering Professor M...in Mexico, produced the first answer when electron microscopy images of the alfalfa shoots confirmed the existence of gold nanoparticles in the roots and along th...