Scientists discover how some viruses take strong hold of cells
...in the current study were derived by cryo-electron microscopy -- the analysis of frozen samples of the virus bound to partial and full receptor molecules. This part of the study was performed at Purdue University. Cloning and sequencing the receptor gene and producing the receptor protein were all performed at ...Survival tactics in bacteria - environmental conditions fit for mankind
...complex was visualised by high-resolution electron microscopy (5). Dr Jon Nield, an author on the paper, modelled known X-ray diffraction derived structures into the calculated PSI supercomplex determined by these electron microscopy-based techniques. This allowed a better understanding of how the light harvest...Never-before-seen look deep inside cancerous tumors
...ospital (MGH) are using multiphoton laser scanning microscopy to visualize individual cells, where they can monitor gene expression, therapy effectiveness and tumor cells interactions with normal cells. The work published in this weeks Nature Medicine demonstrates that the technique could be adapted to measure...New instrument enables remote detection of toxic algae in real time
...ed. In addition to archiving discrete samples for microscopy and nucleic acid and toxin analyses, the instrument also transmits results of probe assays in real-time to a remote location for data processing and interpretation. This capability provides an entirely new means of remotely detecting microorganisms ...When Shewanella meets goethite: Evidence found of recognition between animate and inanimate objects
...t has invented a technique called biological force microscopy and he and his major professor have used it to det...ion and activity. We are applying biological force microscopy to questions pertaining to medical science. For example, biofilm formation affects issues such as th...Virus studies reunite two families of major insect-borne viruses
...thered images of the structure using cryo-electron microscopy and three-dimensional image reconstruction techniques. These methods, which use hundreds of two-dimensional images to develop a three-dimensional view of the virus, allowed the group to determine the overall shape of virus and see the symmetrical arr...US and Japanese scientists develop new test for male infertility
... 17 infertility patients and two fertile donors by microscopy and flow cytometry. They discovered high levels of ubiquitin antibodies on the surface of cells taken from 13 of the 17 infertility patients tested, but not in the two fertile donors. Of the 17 infertility patients, the test confirmed a previous clin...Normal salt levels in the lung of the cystic fibrosis mouse
...n the living trachea. Using confocal fluorescence microscopy Jayraman et al. measure the depth and the concentrations of various ions of the ASL layer produced by normal human and mouse pulmonary tissue, and they show that there is no significant difference in ASL salinity between normal and CFTR-/- mice. The...Study reveals structure of DNA packaging motor in virus
... including X-ray crystallography and cryo-electron microscopy - to determine the structure of the DNA packaging motor in a virus called Bacteriophage phi29. Bacteriophages are viruses that only infect bacteria. They are widely used in laboratory research because they are often similar in structure to human vi...DNA "Motors" are key to virus replication
... including X-ray crystallography and cryo-electron microscopy - to determine the structure of the DNA packaging motor in a virus called Bacteriophage phi29. Bacteriophages are viruses that only infect bacteria. They are widely used in laboratory research because they are often similar in structure to hum...Scientists reveal details of brain cell communication: implications for learning & memory
...cally stimulated brain neurons and used two-photon microscopy to watch as calcium rushed-in to single dendritic spines of these neurons (see figure). These measurements enabled the researchers to determine the number and type of "calcium channels" present at synapses in a region of the brain important for learn...November GEOLOGY and GSA TODAY highlights
...xtinction due to society's activities. Confocal microscopy of fluid inclusions reveals fluid-pressure histories of sediments and an unexpected origin of gas condensate. Andrew C. Aplin et al. In the search for oil, determining how the pressure and composition of oil has changed through time is critical. Th...Ion microscopy pinpoints drugs inside cancer cells
...f the biological and biomedical application of ion microscopy earlier this year in the journal Analytical Chem...de normal and cancer cells can be studied with ion microscopy by placing a stable, or nonradioactive, isotope into a laboratory rat's bloodstream, thereby allowin...Defense Department awards Stanford nearly $5.3 million for a 'revolutionary' biosciences project
...l use robotic microinjection, high-speed automated microscopy and other innovative techniques that McAdams predicts "could completely change the way biological research is done." The robotic microinjection effort is spearheaded by Matthew Scott, a professor of developmental biology, and Olav Solgaard, an assist...Discovery of armored viruses may inspire new designs for nanotechnology
...is strange protein exterior required both electron microscopy and X-ray crystallography, says Hiro Tsuruta, a senior research associate with the Stanford Synchrotron Radiation Laboratory (SSRL) and the Department of Chemistry. "The head of the virus is thousands of times narrower than a human hair," adds Tsuru...Cellular membrane changes associated with acclimation to cold
... and Stroke (NINDS). The NIH scientists used light microscopy and freeze-fracture electron microscopy to examine the tissues of ground squirrels sampled during hibernation while in a hypothermic state a...Single amino acid mutation dramatically alters direction of a molecular 'motor'
...ai, Japan. Higuchi has perfected the use of laser microscopy to trap tiny plastic beads that are attached to these motors. When the motor moves -- that is, when the protein changes its shape -- the bead moves, amplifying the tiny motion of the motor. Through the careful use of this technique and the painsta...Molecular-scale roughness identified as factor in bacterias ability to stick to surfaces
...an explains that now, new forms of molecular-level microscopy have made it possible for the first time to scan both the individual microorganisms and the surfaces to which they attach and also to measure directly their topography and adhesion properties. He and co-author Karl Shellenberger, a master1s degre...Northwestern researchers clone gene responsible for inner ear motor
...hwestern and an expert in nanotechnology, electron microscopy and atomic structures. "One can envisage creating hybrid structures using this protein in artificial membranes that are part of Nano Electro-Mechanical Systems (NEMS), for instance biological pumps that might be used for drug delivery." Dallos an...Virus study reveals how nature 'super-sizes' tiny structures
...ne at Purdue using the techniques of cryo-electron microscopy and three-dimensional image reconstruction. The techniques, which use hundreds of two-dimensional images to develop a three-dimensional view of the virus, allowed the group to determine the overall shape of virus particles and see the symmetrical arr...