Formosan termite may be top concern of entomologists of the new millenium, according to report
...cts in the past half century. Better techniques of microscopy and advances in genetics have taken the discipline into a new era. Studied in their own habitats, insects remain some of the most fascinating creatures on the planet, and since they pre-date humans by millions of years, their ability to survive remai...Researchers glimpse polio virus as it enters host cell
...sing a powerful combination of methodscryoelectron microscopy and X-ray crystallography. Hogle, who is professor of biological chemistry and molecular pharmacology, and his colleagues have interpreted the images, together with the receptorvirus structure, to tell a story of an extremely dynamic particle. From...University of Chicago researchers uncover first steps in cell-cell adhesion process
...ence junctions. These can be seen in fluorescence microscopy images as yellow dots on the outer membranes of adjacent cells. Scientists call these dots "puncta." Because cell-cell adhesion is dependent on calcium concentration, Vasioukhin was able to capture cells in the act of forming puncta. Low level...Study reveals family secret of how viruses enter cells
...infection. Using high-resolution cryo-electron microscopy and three-dimensional image reconstruction techniques, the scientists were able to obtain the first three-dimensional image of how poliovirus 1, one of the three types of polioviruses, binds to a receptor a molecule called CD155 on the cell. CD...Learning how cell's tiny motor powers its mobility
... gold particle to the neck linker andused electron microscopy (performed by Ron Milligan at Scripps Research Institute) to obtain images ofthe kinesin at different stages. Those images revealed that in the absence of ATP analogues, thelinker neck could pivot either forward or backward, but the binding of an ATP...Molecular fats prevent nerve sheath abnormality
...n a series of studies using electron and confocal microscopy to examine very thin cellular layers, Jeffrey L. Dupree, a postdoctoral researcher in Popko's lab and lead-author of the new report found abnormalities in the nodes of Ranvier, the unmyelinated regions of the axon where the sodium channels are locate...3-D structure of human transcription factor proteins revealed
BERKELEY, CA -- A combination of electron microscopy and single particle image analysis has been used t...n the complex were a mystery. Imaging via electron microscopy does not require that a protein be crystallized. Because the Berkeley researchers did not have to c......cher will joincolleagues in Germany in using laser microscopy to track protein molecules onthe surface of cells, research that may eventually lead to an understanding ofhow the immune system combats disease. George Barisas, professor of chemistry and microbiology, has developedtechniques that can follo...Wistar scientists find striking similarities between bacterial virus and human adenovirus
...s-disciplinary scientific tools,including electron microscopy and X-ray crystallography, were used to makedetailed images of the virus. Research on these structures was supported by grants from the NationalInstitutes of Health, the National Science Foundation, the National CancerInstitute, the Fannie E. Rippel ...New microscopy method reveals molecular map of biological surfaces
Using modern microscopy tools, scientists have been able to look at themo...nowing what those molecules actuallyare. Molecular microscopy techniques have been "chemically blind" -- until now. In the September 1999 issue of Nature ...Antibiotics-resistant bacteria
...rotection." The scientists used X-ray and electron microscopy techniques to investigate themolecular structure of the complex made from the Dps protein and the DNA, and tobetter understand how this structure offers protection to the bacterial DNA. "Weare currently investigating the actual signal that triggers t...Under the hood of a cellular transport machine
...aped clathrinlattice, obtained using cryo-electron microscopy by Barbara Pearse andcolleagues at the MRC Laboratory for Molecular Biology in England, with the muchmore detailed view of a portion of the protein derived from X-raycrystallography by Tomas Kirchhausen, Stephen Harrison, and colleagues atHarvard Med......quisite detail. And researchers using atomic force microscopy inconcert with optical tweezers can measure the forces required to pull moleculesapart. But to discover what is happening inside the molecule as it unfolds,Vogel turned to physics professor Klaus Schulten at the University ofIllinois's Beckman Insti......a cell-based assay in combination withhigh-powered microscopy to detect apoptotic cells and to identify the type ofaffected cells in liver tissue sections. The assay, known as TUNEL, detectsfragmented DNA, a hallmark of apoptosis. Transmission electron microscopyallows specific cell types to be identified vis...University At Buffalo Team Discovers How The Cell Nucleus Orchestrates Genetic Processes
...tion to Berezney, the co-authors areAlan Siegel, a microscopy specialist in the department; Jagath Samarabandu,Ph.D., formerly a post-doctoral associate, and Professor Raj Acharya, Ph.D., andgraduate student Rakendu S. Devdher, both of UB's Department of Computer Scienceand Engineering. The work was funded b...Fatal Frog Fungus Found In The United States
...ogs at the National Zoo caught it,he sent electron microscopy images and tissue samples to mycologist JoyceLongcore at the University of Maine in Orono. "As soon as I saw them, Irecognized the organism," she says. Since then, Nichols has found low levels of the fungus in skin from cricketfrogs in Illinois. Like......arch, Hobart identified the fungus using electron microscopy and molecular biology. Berger and Hyatt then demonstrated that it could infect and kill frogs. Strangely, tadpoles do not succumb to this disease. This fits with field reports where tadpoles have been seen in areas after the adults have disappear......s of neuronal tissue and a confocal laser scanning microscopy based image quantification approach, Harald Neumann, Thomas Misgeld, Kenji Matsumoro and Hartmut Wekerle from the Max Planck Institute of Neurobiology at Martinsried/Germany were able to shed some light on the p......laryngology in the U-M Medical School, whodirected microscopy studies for the project. "Once adequate vectors areavailable, gene therapy for genetic-based deafness will become a reality." Frank J. Probst, a graduate student in human genetics in the U-M Medical School,and lead author of the Science paper, ident......elated calcium ATPase, also determined by electron microscopy at comparable resolution, is reported in the same issue of nature (Zhang et al, nature, vol. 392, 23 April 1998, 835). Interestingly, the two structures are similar in the transmembrane domain, but they appear t...