New Study Of BRCA1 Shows No Need For Widespread Screening Of American Women
...ases of breast cancer (at any age),that genotyping might be considered," the researchers conclude. "The emerging picture of BRCA1 population genetics involves complexinteractions of family history, age and genetic history, all of which should betaken into account when considering genetic testing or...Prostate Cancer Switch May Yield Map Of Cancer Machinery, Targets For Drugs
...e genetic switch could open aresearch pathway that might well lead to a road map of the complex changesprostate cancer cells undergo in their progression to a deadly form. Such a roadmap would yield not only molecular markers that would allow physicians to betterpinpoint the stage of a prostate cancer, but...Peptides Implicated In Body's Response To Pain
...ase of neurokinin A,called neurokinin antagonists, might one day be used in combination withmorphine as a t...hese results, if demonstrated in clinical studies, might result in acombination of neurokinin A antagonists and morphine for the treatment ofmoderate to inte...ACS Conference Brief: An Innovative Molecular Assembly
...toror influence biological or chemical activity -- might identify spoiled seafood,carry drugs to tumor sites, or filter uranium ions from nuclear wastewater.The challenge is in designing and building them. UC Davis researchers have been exploring two molecules of particularinterest -- calixarene and porph...Computer Models Find Cost-Effective Solutions For Species Preservation
..." said Camm. "If you factor in theland values, you might have to buy more locations, but they'recheaper to ... wouldchange is how you define a piece of land. It might not becounties. It might be some other designation." "You simply have to have a way of breaking a ma...Chromosomal Abnormalities Key For Prediting Leukemia Outcome
...uch as damage to chromosome 16,as mentioned above) might receive todays standard therapy. A patientwith cytogenetics that indicates a poor prognosis might be recommended forstem-cell transplant or an experimental therapy. Intensification thera...Liquid Crystals Light Up Simple Chemical Test
...g developed at theUniversity of California, Davis, might one day make complex chemical analysesalmost as easy as checking the time on your wristwatch. In contrast to the slow, costly, laboratory-dependent tests now usedfor hundreds of jobs in medicine, industry and research, the Davis "liquidcrystal assay...Needlestick Injuries Common In Female Veterinarians, Study Finds
...someof the medications and exposures veterinarians might experience would bethe same as health care workers who work with people, in terms of anestheticgases, some of the drugs and X-rays, said Jay Wilkins, co-author ofthe study and associate professor of public health at Ohio State University. ...'Mean Gene' Found In Africanized Honey Bees
...d using these queen bees," he says. "Ultimately it might be possible to clone the gene through map-based cloning so that we can better understand how this gene affects stinging behavior. "We made a genetic map of the honey bee using the same techniques used in crop genetics, a technique called quantitative...Butterfly Wings, Beetle Horns Teach Biologists Basic Lesson In Development's Laws
...imentswith a theory that competition for nutrients might be the basis for any observedchanges in the insects, they still don't know what chemical communication takesplace between the fore and hind butterfly wings, or between the beetle's hornsand eyes. Either a hind wing may produce something that inhibits...Seeing How the Brain Changes During Aging
...me of the cognitive and motordeclines in aging and might be able to help determine what doses of the drugwould be most beneficial to an individual. Paper ORGN 4 will be presented by J. S. Fowler from 11:00 a.m. to 12:00 noon,Sun., March 29, in the Convention Center Ballroom A I, Level 3. A nonprofit organi...Insect Taste Buds Target Of Control Method
...cals could then identify candidate substances that might also be less water soluble than those that are already known. It may also allow researchers to design chemicals specifically to stimulate or suppress feeding behavior. Although chemicals that stimulate feeding behavior can be used to convince ...Rapid Progress Reported On New Class Of Anti-Cancer Drugs
...derstand differences betweenthese two enzymes that might aid development of specific inhibitors. H...ylgeranyl transferase does not -- a differencethat might also offer clues to new inhibitors. In his prepared ACS presentation, Casey also cited advan...New Test Opens Window On Corrosive Free-Radical Activity In Individuals
..."And, indeed, we have reason to suspect that there might be quite a degreeof inter-individual difference in...widerange of possible studies to come. Among these might be large-scale clinicaltrials of antioxidant vitamins. The laboratory of chemist Joshua Roka...Tiny Worm Reveals Workings Of Suspected Tumor Protein
.... It also suggests a mechanism for how the protein might work, forging alink to histone acetylation, an are...e thedivision cycle and enter differentiation, E1A might shut this exit, trappingcells in perpetual division. Yet while p300 has been implicated in leukemia,...Dietary Determinants Of Iron Stores In A Free-Living Elderly Population: The Framingham Heart Study
...n analysis. Subjects whose ferritin concentrations might be pathologically elevated because of infection, inflammation, liver disease, or genetic hemochromatosis were excluded from the analysis. After we controlled for sex, age, body mass index, total energy intake, smoking, and use of aspirin and other me...EPA Should Redirect Some Research on Toxic Airborne Particles
...nce from the scientific community, then monitoring might notmeasure the most hazardous air particles or the...eart or lung ailments; studying how particulates might combine with other pollutants to causeshort- and long-term health problems; and developing modelin...Hard Hearts: New Discovery Of Bone In Heart Tissue May Explain Valve Disease
... and why bone forms in the soft tissueof the heart might lead to a preventive or corrective therapy. The next stepsare to develop cell and animal models of valve calcification. Penn colleagues Francis H. Gannon, Carol Reynolds, and Frederick S.Kaplan also participated in this study. Editor's Note......in a significant buildup of soil phosphorus, which might increase the potential for surface water contamination." In part because of phosphorus, the practice of spreading manure on farm land is coming under increasing scrutiny. At the same time that Gore sent out his October message, the Environmental Prot......herapeutic agents against arthritic lesions and might increase the rate of survival in various endotoxin-induced septic shock syndromes....