Tag: "mimics" at biology news

UCSF Team Identifies Two Key Molecules In Asthma; Important Finding For New Therapies That Treat Disease At Cell Level

...earchers conducted the study in a mouse model that mimics humanasthma. The team found that disease begins with the presence in lung tissue of twomolecules, interleukin-4 and interleukin-13, which then link up with a certainreceptor, named the IL-4 receptor alpha. The molecules are hormone-likesubstance...

At Night, Birds May Review The Songs They Learn During The Day

...), are interpreted when the listenersubconsciously mimics the sounds they hear, so that regions associated withspeaking would be active during listening. If this theory were true, then the birds should show activity in the RA, acenter associated with singing, as they listen to songs while awake. Instead,t...

Pioneering Research Could Lead To Treatment

...living tissue. "You can potentially set up mimics of neural architectures in the body,reproducing tissues on the chip," Odde said. "It's a non-contact method. We push the cells with a laser," Renn said,adding, "Who'd have thought that they wouldn't just heat up and die?" You can't pu...

Experimental Antibiotic Promptly Kills Drug-Resistant Bacteria In Studies

...ed in the human body. "Changing the concentrations mimics the pharmacokinetic profile in patients,"Zinner said. "Comparing activities of new drugs against old drugs based onpharmacokinetic considerations allows us to end up with a better idea of thedose of the new drug that gives the same effect as that of ...

Vesicle Chemistry: A New Way To Get Life-Like Reactions

...icalcharacteristics of the membranes in a way that mimics the variations found innature, Zare says. The researchers found two ways to use the vesicles to produce minuscule chemicalreactions. The first approach involves immersing the vesicles in a liquid containing asecond chemical that will react with the c...

Functional Arteries Grown From Cells Using Novel System That Simulates Fetal Environment

... researcher, using a novel "bioreactor" systemthat mimics the fetal environment, has used cells taken from adult pigs'arteries to grow blood vessels that look and act like the real thing.When implanted back into the same animals, the arteries functioned much likenative vessels, said Dr. Laura Niklason, who ...

Designer Molecules: Largest Protein Ever Created From Scratch Has Implications For Novel Drug Delivery And Diagnostics

... produce and suffer from limited shelflives. Novel mimics of these proteins may have enhanced stability and potency. This work was conducted in the Johnson Research Foundation, a funding andresearch organization within Penn's Department of Biochemistry and Biophysicsthat concentrates on the study of phys...

New Class Of Synthetic Capsules That Mimic Biological Cells Has Wide Array Of Potential Uses

...entists have been engineering orgrowing biological mimics for a variety of medical and industrial applications.Bioengineers from the Institute for Medicine and Engineering (IME) at theUniversity of Pennsylvania have designed an artificial capsule that imitatesmany of the qualities of natural cells. The caps...

Transplanted neural stem cells migrate throughout the abnormal brain, reduce disease symptoms

...e fibers. The lack of normal myelin in these mice mimics thedefect seen in many human demyelinating disorders, such as multiple sclerosisand a group of childhood disorders called leukodystrophies. The researchersfound that most of the transplanted cells migrated throughout the brain andmatured into normal...

Green tea can help prevent rheumatoid arthritis

... used and accepted animal model systemthat closely mimics the human disease, clearly shows that mice given green teapolyphenols in water were significantly protected from the development ofarthritis, and, if they did develop the disease, its severity was mild," Haqqiconcluded....

New drug with unusual promise enters ALS pipeline

...t brings about slowdeath of motor neurons and thus mimics essential features of ALS. PEDF-treated sections averaged near-normal neuron counts comparedwith untreated ones. Levels of a key enzyme typically made by healthy cellsunderscored the result. "PEDF may significantly protect spinal mot...

Young rats challenged as model for blood vessel response in older people

...t the disruption in microcirculatory communication mimics that foundin older rats. The Penn State researcher notes, "Even though further studies need to beperformed to more completely describe how responses to I/R injury are alteredwith age, our studies suggest that the mechanisms may be sufficient...

Computers use Darwinian model to 'evolve' fuel additives

...ed and demonstrated how a computerized system that mimics evolution candiscover new gasoline additives for better engine performance. The engineers developed "genetic" algorithms -- or computer instructions --that adapt Charles Darwin's evolutionary model to combine and recombine chemicalcomponents unti...

K-State veterinarian issues canine 'toxic shock' advisory

...ions from dog owners. In many respects the disease mimics thecondition in humans, which can be just as serious. "Streptococcus bacteria cause the 'flesh-eating' disease in humans," Fenwicksaid. "Much of what is known about prevention and treatment has been throughcomparing the human disease with the conditi...

Help with 'screamingly radioactive' storage tanks: Nonradioactive substitute created to aid nuclear waste clean-up

...l thing? But theunusual product, which harmlessly mimics the deadly sludge found in undergroundnuclear waste storage tanks, could save U.S. taxpayers hundreds of millions ofdollars in cleanup costs. It will allow researchers to safely and cheaply determine which radioactivewastes will remain embedded in, a...

'Knockout' mouse may lead to major understanding of human kidney disorder

...nce determined that thiskidney malfunction closely mimics the human disease, IgA nephropathy. Theresearchers also prevented the disorder in the mice by supplying the deficientanimals with the uteroglobin normally made by the non-functioning gene. "This mouse model matches the human form of IgA neph...

Researchers say hormones are key to evolution of insect metamorphosis

...sed as the basis forinsecticides. For instance, JH mimics are used to treat ponds where mosquitoesbreed, thereby blocking their metamorphosis. Such treatment also prevents eggsfrom hatching. The four major insect groups with complete metamorphosis all are thought todescend from a common ancestor, so it appe...

New tool provides major advance for understanding chronic Lyme disease and other illnesses

... the bacterium. The existence of these microbial mimics does not prove they cross-react with the immune system and cause the body to turn on itself, but it is a major step in investigating that possibility. Dr. Marques and her collaborators at NIH and Tufts University's Mark Klempner, M.D., leader of the...

Penny wise and pound-foolish: Study shows need for second pathologist's opinion

...h more difficult, for example, to separate out the mimics from the true cancers. Also, we used to get larger samples of tissue to evaluate; now we get needle biopsies of brain, breast, lymph nodes and prostate glands. That's good for patient recovery from the sampling procedure, but harder for the patholo...

Awareness, quick action key to battling canine bacterial disease

...cal Toxic Shock Syndrome (STSS) because it closely mimics the better known "Toxic Shock" in women caused by toxin producing strains of Staphylococci. Rapid onset, high fever, hypotension and shock are prominent characteristics of STSS in humans. At approximately the same time, a number of unusual cases of n...

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