Newly Discovered Gene Halts Cell Division and May Have Cancer Link
...nd can lead to the formation of new cells that are missing chromosomes -- an event that is notoriously linked to tumor growth. The researchers suspect that certain genetically unstable breast, ovarian, and prostate tumors may have defects in the gene, known as MAD2. The new discovery may open the door to fi...The CIA Would Like To Know What Scientists Are Seeing Over The Rainbow
...es for changes that could lead to disease, such as missing or extra pieces, or parts from different chromosomes that have swapped places. The technique could prove to be extremely valuable in diagnosis of disease based on chromosome alterations. "The value of chromosome examination in understanding the cha...Penn State Wetlands Project Seeks Scientific Evaluation Criteria
...nderstanding how wetlands function. "What we're missing is the personality of wetlands," Brooks says. "What do wetlands do, and why do they do it?" To find the key to the "personality" of wetlands, the Penn State Cooperative Wetlands Center is initiating another three-year wetland project, led by Br...Team Identifies Switch For Tumor Suppressor Gene
...s retinoblastomaoccurs. More commonly, the gene is missing or mutated in manytypes of cancer cells such as those found in the lung, breast,and ovary. "In all cancers, you have cells that proliferateuncontrollably," says Ludlow, the lead investigator and co-authorof the book, Tumor Suppressors: Involvem...Prostate Cancer's Aggressiveness May Be Predicted Early By The Ratio Of Free To Total PSA
...hful waiting means living with cancer and possibly missing an opportunity for cure. "This preliminary study suggests that the free to total PSA ratio may be valuable to the physician at the time of cancer diagnosis to help in the choice of management since the more aggressive cancers need to be treated," sa...Scientists Bridge Gap In Cell Communication
...e. I would guess hundreds of genes." "The missing link," explained Laughon, "has been how the signal switches genes on or off. This protein shuttles from the inner surface of the cell membrane right to the DNA, in one fell swoop." The discovery, Laughon emphasized, will have no immediate me...Jefferson Scientists Find Potential Deadly Effects Of Two Missing Cancer-Suppressor Genes
... sexual development. Somehow, he theorizes, the missing genes throw off normal cell proliferation and d...imes as quickly as they might die with only one missing gene. They expected that. But they didn't expect to find that the combination of missing genes...Wonder Thread: UD Scientists Report First Protein With Collagen And Elastin-Like Domains
...sly, the collagenous regions of preCol-P contain a missing glycine. "When a deletion like this is found in ot...o the animal. So, it's quite fascinating to find a missing glycine in a perfectly functional collagen subjected to great stress and strain in marine environmen...Gene For Last Major Form Of Batten Disease Discovered
...veloped biochemical approach to identify theenzyme missing in the disease. The center is a joint program of ...e of these spots. By isolating and sequencing the missing enzyme andcomparing it to known genes and proteins, the scientists pieced together anearly complete ...Colorado State Scientists Tackle Genetic Makeup Of Obscure Bacteria
..." Inamine said. "There are piecesof the chromosome missing from each of the strains, but in different regions. Wethink this could provide some key clues as to where to look to find the genesthat produce the bacteria that cause disease and the bacteria that don't." Once these genes have been identifie...At Life's Most Sensitive Stage, Embryos Cope With Stress
...s it is no longer needed."UV light, DNA damage and missing frogs Worldwide, scientists have noticed a decline in many species of amphibians.Several apparently have become extinct, yet no single cause for the losses hasbeen identified. Kiesecker, a postdoctoral fellow in biodiversity at Yale, andAndrew Blaust...Duke Researchers Develop First Treatment For Rare Muscle Disease
...n normally. Usually, an important muscle proteinis missing or defective. Many doctors have been unsure if it ...now shown it is possible in principle to replace a missing component ofmuscle and improve muscle strength. "This is a major milestone is our long-term ...Hormones Found In The Brain May Determine How Much You Eat And Affect Obesity And Diabetes
...art of upcoming research will be toproduce rodents missing three genes -- one ligand and the two receptorgenes -- to see if the rats' appetites can be decreased by inhibitingany of them. "These neuropeptides are a very plausible molecular basis forsome classical experiments on eating habits," Yanagi...3-D Structure of Human Tumor-Suppressor Protein Produced
...ng when they shouldn’t. When this protein is missing or inactivated due to mutations in the p16tumor-suppressor gene, cancer can occur. In fact, damage to the p16 proteinis a factor in more than 70 different types of cancer. The researchers have also produced computer-generated pictures of theprotein....Rare Mutation Find May Offer Clues To Treating Osteoporosis
...nucleotides -- building blocks ofproteins -- were missing from chromosome 17. Those without the kinky hair andwith good teeth showed no missing nucleotides. Hart, a dentist and medical geneticist, called the discovery "...UNC-CH Researchers Discover Key Cancer Control Mechanism
...neticlocus, or site on a chromosome, is frequently missing in human cancer." A report on the discovery...ut 50 percent ofcases, Xiong said. The ARF gene is missing in about 40 percent. "When activated, both these genes suppress tumors. When they are absent...Novel Method Of Gene Replacement Reported By University Of Washington Researchers
...f you had a 'typo' in a financial statement, say a missing zero, you'dwant to fix in the right place, not randomly anywhere in the statement," heexplains. "Or if you were correcting an instruction booklet with an error in it,you'd want to insert the corrected instruction in the right place on the rightpage."...Researchers Identify Protein Critical To Urine Concentration
..."This study," said Verkman, "demonstrates that the missing protein is essential for the mouse kidney to form a concentrated urine." Moreover, he said, "the dramatic reaction to the deletion of the protein in mice raises the possibility that other mammalian aquaporins have important physiological functions. ...... the MR95complex, p95, and demonstrated that it is missing completely in NBS patients. "NBS cells behave as if they are unable to recognize DNA damage. If you considerthat, along with our observation that one function of the repair complex is tofind damaged DNA, the two stories begin to mesh into one; namely...