Tag: "mitochondrial" at biology news
Calorie Restriction Reduces Age-Related Muscle Loss
...ntial playerin the aging process: deletions in the mitochondrial
genome, the completeset of genes pertaining to eac...hat's more,they had significantly lower numbers of mitochondrial
gene deletions. "These findings support the notion that abnormalities inmitrochondrial activity may...
Widespread Genus Of Monkeys Gives Up Genealogical Secrets To Columbia Researchers
...termined thenucleotide composition of a segment of mitochondrial
DNA, then compared theresults for genetic similarity and shared genetic changes to draw theirconclusions. The work was supported by the Center for Environmental Researchand Conservation at Columbia University and the National Science Foundation. Th...
The First Rejection: Eggs Sequester Bits Of Sperm For Later Elimination
...ermined that it was composed of what is called the mitochondrial
derivative a crystallized form of the sperm's mito...ia. The fact that the entire sperm, including the mitochondrial
derivative (which makes up about 50 percent of the tail) enters the egg means that a substantial amo...
Cops And Docs Find Evidence In The Other DNA
...s, and medical researchers have linkedmutations in mitochondrial
DNA with Alzheimer's,Parkinson's, neuromuscular diseases and blindness. As interest peaks in mitochondrial
DNA, so has the need for a standard to assureaccuracy in sequencing mitochondrial
DNA. Researchers a...
Genetic Study Reveals Sumatran Tigers Are A Distinct Species From All Mainland Tigers
JUNE 10, 1998--A study of mitochondrial
DNA sequences of tigers, published thismonth in An...d one lion, to serve as a point ofcomparison. The mitochondrial
DNA sequenced from the blood revealed thatSumatran tigers share three unique genetic markers found i...
Tiny Molecular Channels Key To Protecting Heart During Attack
...time. While we're still not sure how opening these mitochondrial
channels mightprotect heart cells from dying, we know that their role is crucial. This willhelp in developing a more effective class of cardioprotective drugs. "There is good reason to believe that, if we were able to recruit thepreconditioni...
Milestone In Mitochondrial Structure Revealed
...s of a cell and causemutations in both nuclear and mitochondrial
DNA. As determined by Jap and his colleagues, the ...n-crystalline protein embedded in the lipids ofthe mitochondrial
inner membrane. Coaxing the protein into forming a crystal, apre-requisite for x-ray imaging, was a ...
Sturgeon, Trout And Telemetry--USGS Research Mixes Science And Technology At American Fisheries Society Annual Meeting
...ean counterparts. Microsatellite (nuclear DNA) and mitochondrial
(extra-nuclear DNA) markers have been developed and used to assess genetic population structure in Atlantic salmon surveyed from throughout the species' range. In particular, salmon from Maine (southern extent of North American range) were compared ...
Pitt Neuroscientists Uncover Mechanism For Neuron Death, Counter Long-Held
Assumptions About This Process
...an spur the formation of free radicals that damage mitochondrial
DNA orinevitably rip holes in the mitochondrial
membrane. Together with Teresa Hasting, Ph.D., assistant professor of neurology atPitt, Dr. ...
Researchers Discover The Pattern Of Inheritance Of Non-Chromosomal DNA
...mall energy factories calledmitochondria. And only mitochondrial
DNA (mtDNA) from the mother passes tothe fetus. Researchers at UT Southwestern Medical Center at Dallas have shown for thefirst time that the multiple copies of mtDNA in a single cell aretransmitted in an organized and finite fashion and not in a ran...
Genetically Speaking, Race Doesn't Exist In Humans
...nary Lineage Templeton analyzed genetic data from mitochondrial
DNA, a form inherited onlyfrom the maternal side; Y chromosome DNA, paternally inherited DNA; and nuclearDNA, inherited from both sexes. His results showed that 85 percent of geneticvariation in the human DNA was due to individual variation. A mere...
SFVAMC-UCSF scientists solve a key protein structure
...is to help fill in gapsin our knowledge of how the mitochondrial
respiratory chain functions. Thisresult also should increase our understanding of how molecular defects in thechain may produce damaging oxygen free radicals, which are thought to play arole in disease and the aging process," says Cecchini. Since th...
With support for the EPA, biologists go out on a genetic limb to help stem migratory songbird declines
...r-round habitat-use. "Our preliminary analyses of mitochondrial
DNA sequences demonstrates that thepopulation structure of a neotropical migrant can be understood," said Dr.Smith, who is on the board of the Point Reyes Bird Observatory. "With a morecomplete set of genetic samples, we hope to identify population u...
Chimpanzee subspecies are genetically mixed and more diverse than humans, according to research in 5 November 1999 Science
... of the chimpanzee genome, mostly from analysis of mitochondrial
DNA. Mitochondrial DNA is separate from the DNA in...said. But Pbo and his colleagues acknowledged that mitochondrial
DNA studies, which show the most diversity in the western population, clash with this version of eve...
Another small cog in the 'hub' of metabolism unraveled
... is succinate dehydrogenase. It is embedded in the mitochondrial
membrane and couples the citric acid cycle to the respiratory chain. The coupled action of these two pathways is a major source of metabolic energy (see Fig. 1).In order to obtain detailed insight into the function of a biological macromolecule such ...
Chromosome centers defined and sequenced for model plant
... arms. In fact, the researchers found an entire mitochondrial
genome embedded near the centromere of chromosome 2. This surprising discovery may shed light on the evolutionary processes that allow DNA from organelles to be exchanged with that from the nucleus. Understanding the centromeres may prove to be a ...
University of Georgia professor writes first book on phylogeography--a field of study that he helped found
...r the cells. Soon, Avise was deep in the study of mitochondrial
DNA (mtDNA), mainly as a training exercise. He did...volution eventually were to emerge from studies of mitochondrial
DNA," said Avise, "but years would pass before relatively clear answers to some of the questions wou...
University of Pittsburgh researchers uncover mitochondrial defect involved with inherited cancers
...ductase (SDHD), that codes for an integral part of mitochondrial
complex II, was defective in families with paraganglioma. By the researchers' reasoning, the defect is likely to cause mitochondria to fail to properly sense the oxygen levels in the cell. And, because of the oxygen-sensing defect, the carotid body...
Hopkins researchers develop a non-invasive screening test for cancer
...D., professor of otolaryngology and oncology, uses mitochondrial
DNA to identify genetic mutations in bladder, head...he cell nucleus. The Hopkins team first identified mitochondrial
mutations linked to bladder, head and neck and lung cancers. Then, they studied paired urine, saliva...
Neanderthal infant yields DNA evidence
... have used molecular genetic techniques to compare mitochondrial
DNA sampled from this infant, who lived 30,000 yea...chnique focuses on the hypervariable region of the mitochondrial
DNA region which evolves rapidly and is commonly used to establish evolutionary relationships betwe...
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