Tag: "modeling" at biology news

'Crystal engineering' helps scientists solve 3-D protein structures

...and to produce computer-based tools for ultimately modeling the structure of any protein from its genetic spelling, or sequence. "This crystallization method has the potential to become a powerful new tool for structural biology and is a great example of the kind of innovation that the Protein Structure Initi...

New software developed at Rensselaer predicts promising ingredients for new drugs

...." Rensselaer researchers noted that predictive modeling is one of a new breed of drug discovery methods that marks a shift in industry practice--a shift away from cell-based assays performed in the lab toward math-based models calculated on the computer. "Our program allows researchers to 'crash te...

Scientists report on the current state of INEEL's nuclear waste contamination

...l as specific contamination, characterization, and modeling issues. Originally, the INEEL site, which is a U....ditions at the complex. Three papers describing modeling approaches to forecast fluid flow and contaminant transport in porous media. One of the papers discu...

Biochemistry and Molecular Biology: Research at the Interface of Biochemistry and Human Health

...y, with symposia on topics such as informatics and modeling of signaling pathways and genetic and molecular resolutions of signaling. Molecular and Cellular Biology of Lipids, organized by Dennis Vance, University of Alberta, with symposia on topics such as lipids and obesity, obesity and minority populat...

Researchers discover 1.2 million new genes in Sargasso Sea microbes

...velopment of sophisticated computer simulation and modeling tools to understand biological systems. Thus, the Genomics: GTL program will also depend on the department's leadership in high performance computing to build the computational infrastructure needed for the new biology of Genomics: GTL. While we ...

World's first databank for all living systems

...encing. The research center will develop computer modeling systems to make predictions at genetic levels and ...exploration of data and comprehensive mathematical modeling of life on Earth, data structures and query languages will be created, guided by a think tank of Cor...

Seeking a mechanical solution to nation's number-one children's illness

...s. Engineers, he says, can answer that question by modeling the functioning of a healthy eustachian tube and using the model to predict the physical behavior of a diseased tube. "Up until recently, researchers have visualized the ear's interior and speculated why the eustachian tube does or does not open," Gh...

Insights gained from molecular modeling may lead to better insecticides

...c protein, but new insights uncovered by molecular modeling could pave the way for more efficient insecticides... two plant families. Predictive three-dimensional modeling of the structures of the proteins detoxifying allelochemicals and insecticides has indicated vivid d...

Secondary complications and restoration of function in SCI

...joint moments help control movement. Measuring and modeling the changes in passive properties following SCI will facilitate the development of better lower-limb musculoskeletal models. These models may aid in the development of enhanced neuroprostheses that use functional electrical stimulation to restore sta...

Statistical technique helps researchers gain more information from a single data run

...roblem at different scales," said Vidakovic. "The modeling should therefore be done at different scales because the materials are very different at the different scales." Analysis of genomic data, especially in the rapid determination of which genetic sequences are coding in which are not. Medical imaging,...

Planning effective bioterror responses

SEATTLE, WA New modeling studies show how bioterror agents may spread throu... great value to using surveillance and statistical modeling to detect early signs of outbreaks such as anthrax," Kleinman said. "The data are routinely collecte...

Rice and M. D. Anderson establish Center for Computational Cancer Research

...ancer treatment, from cancer diagnosis and protein modeling of each patient, to drug discovery and clinical trial design. "The computing needs of the cancer research community are enormous, and with the intellectual expertise in problem solving offered by our collaborators from Rice, we can open doors that we...

Small-molecule inhibitors of anthrax lethal factor identified

...was validated in cell culture. Finally, molecular modeling techniques were used to predict structural features that contribute to inhibitor binding and potency. These techniques revealed a common pharmacophore--a "scaffold" upon which future therapeutics can be built. This pharmacophore will serve as a ba...

Researchers show evolutionary theory adds up

...s, Dr. Solange Rutz, used an original mathematical modeling system and software program to evaluate and compar... theory holds up under the scrutiny of Antonelli's modeling system. The study is published in the latest edition of Nonlinear Analysis: Real World Applications....

Chimp vs. human DNA: what's in the 1% difference

...first sequencing of the human genome. Statistical modeling and computation was done by Clark and by Rasmus Nielsen, a Cornell assistant professor of biological statistics and computational biology. Some of the analysis, which also compared the mouse genome, used the supercomputer cluster at the Cornell Theo...

Lifestyle accounts for difference in chimp, human genome

...first sequencing of the human genome. Statistical modeling and computation was done by Clark and by Rasmus Nielsen, a Cornell assistant professor of biological statistics and computational biology. Some of the analysis, which also compared the mouse genome, used the supercomputer cluster at the Cornell Theo...

EGFR: A molecular lab rat let loose in systems biology

...promise, outfitted with high-powered computing and modeling capabilities that are being brought to bear on the fundamental problems of human physiology and disease pathology. And what undiscovered country does H. Steven Wiley and his colleagues at the Pacific Northwest National Laboratory choose to flood wit...

Little-studied waves in the heart may be cause of defibrillation failure

... high-speed imaging, data processing and numerical modeling are just now allowing their quantitative analysis as damped, propagating waves. To study the damped waves, Wikswo's team initiated a wave with a strong stimulus that moved smoothly across the heart. They then created a damped wave with a weaker stimu...

Small-molecule inhibitors of botulinum neurotoxin identified

...ormance liquid chromatography. Finally, molecular modeling techniques were used to predict structural feature...Testing in cell culture will be followed by animal modeling once the most promising candidates have been identified. Study collaborators were Sina Bavari, James...

Study predicts loss of monarch winter refuges

...study represents the first use of ecological niche modeling to predict the seasonal distributions of a migratory species under climate change. Oberhauser and Peterson will now use the technique to study how monarchs will fare in their breeding areas within the United States. If the summer breeding areas shoul...

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(Date:4/14/2014)... treat children with uncomplicated acute appendicitis is a reasonable ... fewer missed school days, according to a pilot study. ... Hospital and published online April 12 in the ... the first prospective study on nonoperative management of acute ... , Researchers enrolled 77 patients age 7 to 17 ...
(Date:4/14/2014)... 2014, Perth, Australia. Drug discovery company Proteomics International ... of a companion diagnostic (CDx) test with the ... The research team authenticated the panel of biomarkers ... samples. Seven biomarkers were validated at high stringency ... The mass spectrometry data was then cross-validated using ...
(Date:4/14/2014)... 2014) When it comes to the cost and ... Patients get the best care when they are treated ... extensive experience in their current job, according to a ... and Columbia Business School. The study was published in ... Applied Economics . , The review of more ...
(Date:4/13/2014)... STANFORD, Calif. A low-cost empowerment program for ... and sexual harassment of these girls, who live ... and are frequently attacked, a large new study ... Stanford University School of Medicine, Lucile Packard Children,s ... No Worldwide, validated the program,s effectiveness in combating ...
(Date:4/11/2014)... the processes that control brain cell production could pave ... brain-related disorders. , Scientists have gained new understanding of ... how and when nerve and brain cells are formed ... and keeps it healthy. Their findings could help explain ... which is a fundamental characteristic of many diseases including ...
Breaking Medicine News(10 mins):Health News:Antibiotics alone are a successful treatment for uncomplicated acute appendicitis in kids 2Health News:Antibiotics alone are a successful treatment for uncomplicated acute appendicitis in kids 3Health News:Longer nurse tenure on hospital units leads to higher quality care 2Health News:Empowerment program greatly decreases incidence of rape, Stanford/Packard-led study finds 2Health News:Empowerment program greatly decreases incidence of rape, Stanford/Packard-led study finds 3Health News:Empowerment program greatly decreases incidence of rape, Stanford/Packard-led study finds 4
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