Tag: "models" at biology news
Study offers new model for breast cancer
...t cancer cells in culture. Attempts to create live models
by injecting human cancer tissues beneath the skin of mice have been ineffective because the cancer cells used in these experiments typically are bred in Petri dishes and end up bearing little resemblance to human cancer. In addition, these tumor cel...
Study reveals important new factor in cystic fibrosis lung inflammation
...of this molecule (lipoxin-like molecules) in mouse models
of CF, the molecules do what we'd like them to do -- suppress acute inflammation, switch on the chronic inflammatory process and ameliorate disease -- suggesting that this class of molecules might have therapeutic potential in CF," says Christopher K...
JCI table of contents, 15 March 2004
...e use of agents that block CCR2 action in RA mouse models
partially reduces relevant RA symptoms, indicating... results, however, resulted in two different mouse models
for RA that had the CCR2 gene deleted: in both cases, instead of an amelioration of RA, the mice had...
Pittsburgh NMR Center for Biomedical Research at Carnegie Mellon
...aking significant advances in understanding animal models
of autoimmune diseases using magnetic resonance microscopy (MRM). Used to study living animals, MRM provides near cellular detail of internal organs. Center scientists are developing quantitative methods to perform "virtual" pathologic analyses of di...
New approach limits damage after heart attack and improves survival, say Scripps Research scientists
...ssue from irreversible damage." Using laboratory models
that are designed to mimic the pathology of heart ...tical human therapies. Using extensive preclinical models
that mirror human heart attacks, TargeGen scientists report that 40 to 60 percent reductions in infa...
Germ-free transparent fish open new window into gut development
...their friendly gut bacteria, we need simple animal models
that can function as living test tubes," explains ...ncipal investigator Jeffrey I. Gordon, M.D. "These models
are key to identifying the genes and chemicals that allow friendly bacteria to enhance our health." ...
Wasps' brains enlarge as they perform more demanding jobs
...ocial insects such as wasps, honeybees and ants as models
to understand the role of neuroplasticity in driving complex social behaviors such as the division of labor. The wasps he studied, Polybia aequatorialis, live in colonies of 2,000 or more workers and the adults undergo striking behavioral changes a...
Are you slow in coordinating your thoughts?
... for networks of pulse-coupled oscillators, simple models
of neural networks in the brain (Physical Review Letters 92: 074101, 2004). To analyze the impact of network structure on its function the scientists use the theory of random matrices. Initiated by the work of Wigner on correlations of energy levels...
Educational program increases some safety behaviors for older drivers
...edge Enhances Your Safety (KEYS), was motivated by models
of health behavior change and health promotion. It was administered one-on-one in two sessions in an eye clinic conference room. The first session was individually tailored to the participant's own driving needs, lifestyle and visual problems. The...
Cancer health risk significantly underestimated by EPA's ambient model estimates
...mpounds (VOCs) is vastly underestimated by current models
that rely solely on ambient emissions. Researchers...s clearly on the right track in its development of models
that will take into account indoor sources providing a true representation of the health risk from V...
Should publicly funded research be free and available to the public?
...hink it is a good thing that we will now have both models
in play. PloS has made an impressive start, with good papers, and there is every reason to wish them success. Interestingly, both ways of making scientific results available to the community are facing real challenges. Ours is that we are already mak...
JCI table of contents, March 1 2004
... from arrhythmia and how the evolution of computer models
of the heart will help researchers answer important questions that remain about these conditions. TITLE: A simulation study of the effects of cardiac anatomy in ventricular fibrillation AUTHOR CONTACT: Alan Garfinkel University of California Los Ange...
Drugs limit deadly side effects of graft-versus-host disease
...e found similar anti-inflammatory effects in mouse models
used for research on lupus and sepsis," says Reddy...we selected for this research are known to be good models
for what happens in humans after a bone marrow transplant. So there are reasons to believe that we m...
Inhibition of insulin-like growth factor receptor-1 as promising anticancer therapeutic
...ffect of chemotherapy in clinically relevant mouse models
of multiple myeloma and other hematological malignancies. The researchers also identify two small molecules that are selective inhibitors of IGF-1R and are active anticancer agents against tumors that contain IGF-1R. These small molecules represent...
Current smoke alarms pass life-saving tests
...s--ionization and photoelectric.* Some combination models
are sold. According to the two-year NIST home smoke alarm performance study, ionization smoke alarms respond faster to flaming fires, while photoelectric smoke alarms respond quicker to smoldering fires. The report concluded that, despite these diffe...
Seeking a mechanical solution to nation's number-one children's illness
...he eustachian tube. He also developed mathematical models
to interpret and quantify those properties. Mathem...ly doing physical experiments in a laboratory. The models
also enable researchers to change the parameters of their experiments in a more precise manner. Afte...
Dana-Farber scientists discover natural blocker of HIV-1 virus
...(HIV-1). The finding could lead to improved animal models
of AIDS for research and suggests that that a simi...s from Africa and Asia) and is a hurdle to making models
of human AIDS in these monkeys. Authors in addition to Stremlau and Sodroski are Christopher Owens,...
Cell cycle research earns biologist Virginia's top scientist award
...ision, Tyson and his colleagues build mathematical models
of interacting genes and proteins and solve the eq...echnology and Economics, Tyson builds mathematical models
of genes and proteins and their chemical interactions and then simulates the changing patterns of mo...
Purdue scientists: Genetically modified fish could damage ecology
...ons that the group's research is based on computer models
as well as observation of actual fish mating behavior - behavior that took place within a controlled laboratory setting rather than in nature, where other factors could influence the outcome. Consequently, these ideas should not be taken as gospel un...
Secondary complications and restoration of function in SCI
...of better lower-limb musculoskeletal models. These models
may aid in the development of enhanced neuroprostheses that use functional electrical stimulation to restore standing and walking in individuals with paraplegia. Variable-frequency-train stimulation not effective in reducing muscle fatigue after SCI...
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