Extended-release niacin effective in low doses for diabetics, say UT Southwestern researchers
... Medical Center at Dallas researchers, who led the multicenter trial. The researchers report in today's issue of ...ients with diabetes." Also participating in the multicenter trial were investigators from Kos Pharmaceuticals; the Diagnostic Clinic of Houston; the Internation...Study suggests coenzyme Q10 slows functional decline in Parkinsons disease
Results of the first placebo-controlled, multicenter clinical trial of the compound coenzyme Q10 suggest that it can slow disease progression in patients with early-stage Parkinson's disease (PD). While the results must be confirmed in a larger study, they provide hope that this compound may ultimatel...First genetic findings in children and adolescents with obsessive-compulsive disorders
...lay a role in OCD disease etiology. In the present multicenter study, a positive association was identified between OCD and a sequence variant of a serotonergic receptor gene (A-allele of the 5-HT2A-receptor promoter polymorphism 1438G/A). The association suggests that this genetic phenotype is a risk factor for...Drug-resistant seizures often take years to develop
...inois University in DeKalb, who is part of a large multicenter team directed by Susan Spencer, M.D., at Yale University in New Haven, Connecticut. The study was funded by the National Institute of Neurological Disorders and Stroke (NINDS) and appears in the January 28, 2003, issue of Neurology.* In the new ...Results from open-label Raptiva study suggest continued benefit with long-term treatment
... announced preliminary results from an open-label, multicenter trial evaluating the long-term safety and tolerabi...ients were enrolled in this continuing open-label, multicenter study. 41 percent of patients (140/339) achieved 75 percent or greater improvement in Psoriasis Are...Phase III study results with Raptiva in the treatment of psoriasis presented at Annual AAD meeting
...e psoriasis." Data from 15 months of an open-label multicenter trial evaluating the safety and tolerability of Ra...ted In the double blind, placebo-controlled, multicenter study, 556 patients were randomized in a 2 to 1 ratio to receive weekly subcutaneous doses of 1 mg/k...Anti-HIV drugs save vision, improve outlook for AIDS patients
...impairment than those who did not. In the second, multicenter study, published in the May issue of the journal Ophthalmology, AIDS patients with vision loss reported a lower vision-related quality of life, although those who took HAART reported higher overall quality of life than those who did not. AIDS patien...Benefits of lung surgery reported for emphysema patients
...herapy alone (7.9 percent versus 1.3 percent). The multicenter study, called the National Emphysema Treatment Trial (NETT), was designed to evaluate the effectiveness and safety of adding LVRS to medical management including pulmonary rehabilitation for advanced emphysema patients. The findings are being present...New Zealand biotech: An emerging global presence
...s involved in three clinical trials (including one multicenter U.S. Phase IIb trial) evaluating efficacy of mycobacterial products for the treatment of psoriasis and atopic dermatitis (eczema), skin conditions that affect millions, including many children. Genesis' Plant Sciences Division focuses on novel hormon...Common treatment for depression is safe and effective for Alzheimer's patients
...n the results, Lyketsos and his team are leading a multicenter clinical trial to investigate the long-term benefits of sertraline for patients with Alzheimer's and to determine how well the treatment eases the burden of caregivers. According to the National Institute on Aging, up to 4 million Americans suffer f...Lifestyle changes clinically effective
...th, Eating, Activity and Lifestyle (HEAL) study, a multicenter study designed to examine the associations between physical activity, diet, weight, hormones, breast density, and other influences on breast cancer prognosis among newly diagnosed breast cancer survivors. Physical activity levels and breast density ...Zadaxin in triple therapy shows 61% response for hepatitis C non-responders
...CV load measured at weeks 12, 24, 48, and 72. This multicenter study is being conducted by a team lead by Dr. Jorge L. Poo, Chief Scientific Officer of CIF-Biotech at the Medica Sur hospital in Mexico City ( www.cifbiotec.org.mx ). Dr. Poo concluded, "These data suggest that ZADAXIN adds to the efficacy of pegy...Can EPO prevent loss of brain function in schizophrenia?
...cted in schizophrenic humans. First results of the multicenter trial running in Germany will be available in 2004....Landmark, pivotal Phase IIb/III trial of biotoxin for cancer pain begins
...cer pain, further study of tetrodotoxin in a large multicenter controlled trial is warranted. We believe that the current Phase IIb/III study will be one of the largest and most important Canadian clinical trials conducted to date to evaluate the efficacy and safety of a drug for medically refractory cancer pain...Commercialization deal boosts hope for new sickle-cell drug
...le-cell disease. The companies will collaborate on multicenter Phase III trials, the final step before seeking marketing approval from the U.S. Food and Drug Administration. Current treatment options are few for sickle-cell disease, a genetic blood disorder that affects millions of children and adults worldwi...Hopkins scientists use blood proteins to detect ovarian cancer
...for their test, the Hopkins scientists conducted a multicenter study and screened a total of 195 blood samples from two groups of ovarian cancer patients, healthy people, and patients with benign ovarian tumors. A sophisticated bioinformatics program was used to select proteins present at unusually high or low...Reducing allergens in the home helps inner-city children with asthma
...enter at Dallas researcher who participated in the multicenter study. The National Institutes of Health study, reported in today's The New England Journal of Medicine, showed that an environmental intervention designed to reduce allergen levels in the home indeed led to a marked reduction of irritants. As a r...