Carnegie Mellon neuroscientist develops tool to image brain function at the cellular level
...ed on the decades-long understanding that a neuron must turn on new genes to firmly encode memories in the brain. Each time c-fos is activated in Barth's transgenic mouse, so is GFP. The result is an animal whose neurons literally glow when they are activated by stimuli. "The fosGFP mice offer better acc...Cell death protein has surprising role in cell migration
...migration problem improved, the overexpressed gene must have fixed or compensated for the lack of functional Rac," says Montell. The fruit fly ovary consists of about 100 egg chambers, each made of 16 cells -- 15 "nurse" cells and one oocyte, which becomes the egg -- surrounded by a layer of several hund...Comparing primate genomes offers insight into human evolution
...sts have argued that to understand human nature we must understand the behavior of apes. In the social interactions and organization of modern primates, the theory goes, we can see the evolutionary roots of our own social relationships. In the genomic era, as scientists become more adept at extracting bio...Secret behind hard exoskeletons, spreading wings revealed
...5 years ago, so we are quite excited." All insects must shed their old outer skin or cuticle periodically in order to grow. The new outer shell then hardens and its color darkens. Both processes take place through the activation of a series of five hormones. The structure, genetic sequence and biochemical...$1.86 billion boost for UK science and innovation
...dditional $1.86bn (1bn) commitment. The Government must now work with universities, Regional Development Agencies and businesses to boost the transfer of knowledge to industry, bolstering the UK's position as a growing hub for global knowledge-intensive businesses." The ten year investment framework for s...Sequential signals choreograph embryonic tubule formation
...y, liver and breast. All of these cellular changes must be carefully coordinated over space and time. Dr. Keith E. Mostov from the Department of Anatomy at the University of California, San Francisco, and colleagues investigated the HGF-stimulated molecular mechanisms that are required for coordination of...'Extinct' bird rediscovered in Mexico
...n the birds, scientists believe that other factors must have contributed to the decline, because the Cozumel Thrasher likely survived hurricanes for millennia. Introduced species, especially predatory boa constrictors introduced to the island in 1971 and now abundant, may also have had a disastrous effect......already practising." The Analyst "... an absolute must for anyone studying forensic science or law ... this splendid book is packed with information ... excellent value for money ..." Education in Chemistry "... I would have no hesitation in recommending this book ..." Chromatographia "... a readable boo...Key principles for the foundation of a European Research Council (ERC)
...pport basic research, a European Research Council, must form a cornerstone of the European Research Area. ...bal position in science and research. A future ERC must include all areas of research, i.e., the humanities and social sciences as well as the natural scien...Asian bird flu became highly pathogenic through continued circulation and gene swapping
...utbreaks of H5N1 in East Asian poultry populations must be rapidly and effectively controlled to prevent H...r another poultry epidemic, officials in East Asia must follow Hong Kong's lead," Webster said. "Otherwise, H5N1 will likely continue to infect birds and ot...UCSD undergraduates participate in collaborative studies abroad on cyberinfrastructure
...ed to be U.S. citizens or permanent residents, and must be enrolled as full-time students at UCSD with a minimum GPA of 3.0 (out of 4.0). In the fall quarter students will participate in the PRAGMA 7 workshop, to be held in San Diego, and will be expected to submit papers on their experiences abroad and ...Researchers discover how worms' noses sense oxygen
...sed by C. elegans may be used by other animals who must avoid low-oxygen environments, including fish. Hum...fuses much more slowly in those environments, they must evolve ways to sense oxygen and react to changes in oxygen levels." Marletta's students continue to...Plant pathologists look to forensics to aid in biosecurity
...ttribute the crime to a specific perpetrator, data must be sufficiently specific to stand up in a court of law," said Fletcher. New research is needed to expand knowledge on the genetics, evolution, biology, and host reactions of key microbes. "Guidelines for sample collection and attention to non-pathoge...FSU scientists develop new tests to detect nut allergens in processed food
...nts available," said Sathe. Vulnerable individuals must scrupulously avoid all contact with the offending ...etection will help protect sensitive consumers who must rely upon accurate labeling, as well as food industry and regulatory agencies who monitor the presen...Technology could enhance accuracy of breast biopsy
...dditional 6 percent of the women who have biopsies must have the procedures repeated because the results are inconclusive. Ramanujam and graduate students Carmalyn Lubawy and Changfang Zhu are harnessing the power of light to add another dimension of information about the tissue properties at the needle ...UCSD team determines cellular stress within body is critical
...iruses or bacteria, the cells of the immune system must proliferate very rapidly." The studies were supported by a grant from the National Institutes of Health, with shared core facility resources supported by a grant from the National Cancer Institute. In addition to Ho, the paper's authors included fir......ty came late in human evolution and its advantages must have compensated somehow for the disabilities and diseases of older age, when gene expressions uncommon in younger adults become more frequent," the authors noted. "There has been a lot of speculation about what gave modern humans their evolutionary ...Protein controls acid in cells by direct detection of volume changes, study finds
...rent parts of the body. As cancer cells move, they must change their volume, protruding at one end and retracting on the other. Dr. Hilgemann said other researchers speculate that NHE1 is at the head of the cell as it is moving, and is always rearranging itself to be at the cell's head. "While the cancer ...Combination of gene therapy and gene silencing prevents neurodegenerative disease
...that is toxic to cells. Thus, a successful therapy must remove or suppress the disease-gene rather than simply add a corrected version. "Although we know how to put genes into cells, the difficulty we face in treating dominant diseases is how to remove or silence genes," Davidson explained. "With our appr......ma factor (EF). To gain entry into host cells, PA must recognize a receptor on the surface of the target cell. Once PA has bound to the cell, it then enables EF and LF to bind and form a pore through which PA forces EF and LF into the cell in a syringe-like action. Liddington's laboratory, together with...